Gene Information
Gene NameABHD2
OrganismHomo sapiens (Human)
Gene Length425
Protein NamesMonoacylglycerol lipase ABHD2 (EC 3.1.1.23) (2-arachidonoylglycerol hydrolase) (Abhydrolase domain-containing protein 2) (Acetylesterase) (EC 3.1.1.6) (Lung alpha/beta hydrolase 2) (Progesterone-sensitive lipase) (EC 3.1.1.79) (Protein PHPS1-2)
Target NameNA
Target TypeNA
Gene Age1488 ( ENSG00000140526 )
Evolutionary StageEuk+Bac
AlphaFoldDBP08910
Gene CardABHD2
Uniprot IDP08910
PfamPF00561
In ASDno
Allosteric Predictionno (-0.516620095)
Ortholog in AnimalsAlpaca_ ABHD2 ( ortholog_one2one )
Dog_ ABHD2 ( ortholog_one2one )
GuineaPig_ ABHD2 ( ortholog_one2one )
Macaque_ ABHD2 ( ortholog_one2one )
Mouse_ Abhd2 ( ortholog_one2one )
Pig_ ABHD2 ( ortholog_one2one )
Rat_ Abhd2 ( ortholog_one2one )
Rabbit_ ABHD2 ( ortholog_one2one )
OhnologsNA
ParalogsABHD3, ABHD15, ABHD1
TissueNA
Tissue SpecificityPresent in sperm (at protein level). {ECO:0000269|PubMed:26989199}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs17851730 
Subcellular location [CC]Cell projection, cilium, flagellum membrane {ECO:0000305|PubMed:26989199};
Single-pass type II membrane protein {ECO:0000305}. Cell membrane {ECO:0000305};
Single-pass type II membrane protein {ECO:0000305}.
Mouse PG classificationNA
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