| Gene Information | |
|---|---|
| Gene Name | ABHD14B |
| Organism | Homo sapiens (Human) |
| Gene Length | 210 |
| Protein Names | Putative protein-lysine deacylase ABHD14B (EC 2.3.1.-) (Alpha/beta hydrolase domain-containing protein 14B) (Abhydrolase domain-containing protein 14B) (CCG1-interacting factor B) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1064 ( ENSG00000114779 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | Q96IU4 |
| Gene Card | ABHD14B |
| Uniprot ID | Q96IU4 |
| Pfam | PF12697 |
| In ASD | no |
| Allosteric Prediction | no (-1.307686612) |
| Ortholog in Animals | Alpaca_ ABHD14B ( ortholog_one2one ) Dog_ ABHD14B ( ortholog_one2one ) GuineaPig_ ABHD14B ( ortholog_one2one ) Macaque_ ABHD14B ( ortholog_one2one ) Mouse_ Abhd14b ( ortholog_one2one ) Pig_ ABHD14B ( ortholog_one2one ) Rat_ Abhd14b ( ortholog_one2one ) Rabbit_ ABHD14B ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | SERHL2, MEST, EPHX4, ABHD6, ABHD8, ABHD11, EPHX2, ABHD5, ABHD4, BPHL, ABHD14A, EPHX3 |
| Tissue | NA |
| Tissue Specificity | Ubiquitous (PubMed:14672934). Detected in spleen, thymus, prostate, testis, ovary, small intestine, colon, peripheral blood leukocyte, heart, placenta, lung, liver, skeletal muscle, pancreas and kidney (PubMed:14672934). {ECO:0000269|PubMed:14672934}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1IMJ (X-ray 2.20A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:11053859, ECO:0000269|PubMed:14672934, ECO:0000269|PubMed:31478652}. Nucleus {ECO:0000269|PubMed:11053859, ECO:0000269|PubMed:14672934, ECO:0000269|PubMed:31478652}. Note=Predominantly cytoplasmic. {ECO:0000269|PubMed:14672934}. |
| Mouse PG classification | NA |
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