| Gene Information | |
|---|---|
| Gene Name | ABHD12 |
| Organism | Homo sapiens (Human) |
| Gene Length | 398 |
| Protein Names | Lysophosphatidylserine lipase ABHD12 (EC 3.1.-.-) (2-arachidonoylglycerol hydrolase ABHD12) (Abhydrolase domain-containing protein 12) (hABHD12) (Monoacylglycerol lipase ABHD12) (EC 3.1.1.23) (Oxidized phosphatidylserine lipase ABHD12) (EC 3.1.-.-) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000100997 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q8N2K0 |
| Gene Card | ABHD12 |
| Uniprot ID | Q8N2K0 |
| Pfam | PF12146 |
| In ASD | no |
| Allosteric Prediction | no (-0.359099962) |
| Ortholog in Animals | Alpaca_ ABHD12 ( ortholog_one2one ) Dog_ ABHD12 ( ortholog_one2one ) GuineaPig_ ABHD12 ( ortholog_one2one ) Macaque_ ABHD12 ( ortholog_one2one ) Mouse_ Abhd12 ( ortholog_one2one ) Pig_ ABHD12 ( ortholog_one2one ) Rat_ Abhd12 ( ortholog_one2one ) Rabbit_ ABHD12 ( ortholog_one2one ) |
| Ohnologs | ABHD12B |
| Paralogs | ABHD13, ABHD16B, ABHD17A, ABHD17C, ABHD12B, ABHD16A, ABHD17B |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs587777604 rs772987424 rs746748 rs587777602 |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000269|PubMed:30237167}; Single-pass membrane protein {ECO:0000255}. |
| Mouse PG classification | HPG |
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