| Gene Information | |
|---|---|
| Gene Name | ABCG4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 646 |
| Protein Names | ATP-binding cassette sub-family G member 4 (EC 7.6.2.-) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1714 ( ENSG00000172350 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q9H172 |
| Gene Card | ABCG4 |
| Uniprot ID | Q9H172 |
| Pfam | PF01061; PF19055; PF00005 |
| In ASD | no |
| Allosteric Prediction | no (-0.97992217) |
| Ortholog in Animals | Alpaca_ ABCG4 ( ortholog_one2one ) Dog_ ABCG4 ( ortholog_one2one ) GuineaPig_ ABCG4 ( ortholog_one2one ) Macaque_ ABCG4 ( ortholog_one2one ) Mouse_ Abcg4 ( ortholog_one2one ) Pig_ ABCG4 ( ortholog_one2one ) Rat_ Abcg4 ( ortholog_one2one ) Rabbit_ ABCG4 ( ortholog_one2one ) |
| Ohnologs | ABCG1 |
| Paralogs | ABCG8, ABCG5, ABCG1, ABCG2 |
| Tissue | cerebellar.hemisphere, cerebellum |
| Tissue Specificity | Expressed specifically in the brain and the eye. {ECO:0000269|PubMed:11856881, ECO:0000269|PubMed:12183068}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs35060365 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:27228027}; Multi-pass membrane protein {ECO:0000255}. Cytoplasmic vesicle membrane {ECO:0000250|UniProtKB:Q91WA9}; Multi-pass membrane protein {ECO:0000255}. Endosome membrane {ECO:0000250|UniProtKB:Q91WA9}; Multi-pass membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
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