| Gene Information | |
|---|---|
| Gene Name | TTYH1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 450 |
| Protein Names | Protein tweety homolog 1 (hTTY1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 886 ( ENSG00000167614 ) 3 ( ENSG00000275650 ) 3 ( ENSG00000276537 ) 3 ( ENSG00000276887 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9H313 |
| Gene Card | TTYH1 |
| Uniprot ID | Q9H313 |
| Pfam | PF04906 |
| In ASD | no |
| Allosteric Prediction | no (-0.267553588) |
| Ortholog in Animals | Alpaca_ TTYH1 ( ortholog_one2many ) Dog_ TTYH1 ( ortholog_one2one ) GuineaPig_ TTYH1 ( ortholog_one2one ) Macaque_ TTYH1 ( ortholog_one2one ) Mouse_ Ttyh1 ( ortholog_one2one ) Pig_ TTYH1 ( ortholog_one2one ) Rat_ Ttyh1 ( ortholog_one2one ) |
| Ohnologs | TTYH3, TTYH2 |
| Paralogs | TTYH2, TTYH3 |
| Tissue | brain, cerebral.cortex |
| Tissue Specificity | Expressed in brain, eye, ovary and testis, and at lower levels in muscle, placenta, liver and lung. {ECO:0000269|PubMed:17116230}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 7P5J (EM 4.00A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. |
| Mouse PG classification | NA |
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