Gene Information
Gene NameABCF1
OrganismHomo sapiens (Human)
Gene Length845
Protein NamesATP-binding cassette sub-family F member 1 (ATP-binding cassette 50) (TNF-alpha-stimulated ABC protein)
Target NameNA
Target TypeNA
Gene Age1292 ( ENSG00000204574 )
3 ( ENSG00000206490 )
3 ( ENSG00000225989 )
3 ( ENSG00000231129 )
3 ( ENSG00000232169 )
3 ( ENSG00000236149 )
3 ( ENSG00000236342 )
Evolutionary StageEuk+Bac
AlphaFoldDBQ8NE71
Gene CardABCF1
Uniprot IDQ8NE71
PfamPF00005; PF12848
In ASDno
Allosteric Predictionno (-0.237815672)
Ortholog in AnimalsAlpaca_ ABCF1 ( ortholog_one2one )
Dog_ ABCF1 ( ortholog_one2one )
GuineaPig_ ABCF1 ( ortholog_one2one )
Macaque_ ABCF1 ( ortholog_one2one )
Mouse_ Abcf1 ( ortholog_one2one )
Pig_ ABCF1 ( ortholog_one2one )
Rat_ Abcf1 ( ortholog_one2one )
Rabbit_ ABCF1 ( ortholog_one2one )
OhnologsNA
ParalogsABCF3, ABCF2
TissueNA
Tissue SpecificityUbiquitous. {ECO:0000269|PubMed:9790762}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 5ZXD  (X-ray  2.29A 
DBSNP rs6902544 
Subcellular location [CC][Isoform 2]: Cytoplasm {ECO:0000269|PubMed:19570978}. Nucleus, nucleoplasm {ECO:0000269|PubMed:19570978}. Nucleus envelope {ECO:0000269|PubMed:19570978}.
Mouse PG classificationNA
click here to return to the previous page