| Gene Information | |
|---|---|
| Gene Name | ABCD3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 659 |
| Protein Names | ATP-binding cassette sub-family D member 3 (EC 3.1.2.-) (EC 7.6.2.-) (70 kDa peroxisomal membrane protein) (PMP70) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1064 ( ENSG00000117528 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | P28288 |
| Gene Card | ABCD3 |
| Uniprot ID | P28288 |
| Pfam | PF06472; PF00005 |
| In ASD | no |
| Allosteric Prediction | no (-0.39648006) |
| Ortholog in Animals | Alpaca_ ABCD3 ( ortholog_one2one ) Dog_ ABCD3 ( ortholog_one2one ) GuineaPig_ ABCD3 ( ortholog_one2one ) Macaque_ ABCD3 ( ortholog_one2one ) Mouse_ Abcd3 ( ortholog_one2one ) Pig_ ABCD3 ( ortholog_one2one ) Rat_ Abcd3 ( ortholog_one2one ) Rabbit_ ABCD3 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | ABCD4, ABCD1, ABCD2 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);0.08(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs121917999 |
| Subcellular location [CC] | Peroxisome membrane {ECO:0000269|PubMed:10704444, ECO:0000269|PubMed:16344115, ECO:0000269|PubMed:17761678, ECO:0000269|PubMed:24333844, ECO:0000269|PubMed:29397936}; Multi-pass membrane protein {ECO:0000255}. |
| Mouse PG classification | HPG |
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