Gene Information
Gene NameABCD1
OrganismHomo sapiens (Human)
Gene Length745
Protein NamesATP-binding cassette sub-family D member 1 (EC 3.1.2.-) (EC 7.6.2.-) (Adrenoleukodystrophy protein) (ALDP)
Target NameNA
Target TypeNA
Gene Age1064 ( ENSG00000101986 )
Evolutionary StageEuk+Bac
AlphaFoldDBP33897
Gene CardABCD1
Uniprot IDP33897
PfamPF06472; PF00005
In ASDno
Allosteric Predictionno (-0.554409797)
Ortholog in AnimalsAlpaca_ ABCD1 ( ortholog_one2one )
Dog_ ABCD1 ( ortholog_one2one )
GuineaPig_ ABCD1 ( ortholog_one2one )
Macaque_ ABCD1 ( ortholog_one2one )
Mouse_ Abcd1 ( ortholog_one2one )
Pig_ ABCD1 ( ortholog_one2one )
Rat_ Abcd1 ( ortholog_one2one )
Rabbit_ ABCD1 ( ortholog_one2one )
OhnologsABCD2
ParalogsABCD2, ABCD4, ABCD3
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNULL(Chimpanzee);0.001000(Mouse);NULL(Rat);0.040000(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 7RR9  (EM  3.50A  )  7RRA  (EM  4.40A  )  7SHM  (EM  3.14A  )  7SHN  (EM  3.10A  )  7VWC  (EM  3.53A  )  7VX8  (EM  2.80A  )  7VZB  (EM  3.59A  ) 
DBSNP rs183021839  rs1557052294  rs1557052302  rs1569540688  rs2091705631  rs1557052306  rs398123110  rs1557052351  rs1557052351  rs193922097  rs128624216  rs1057517954  rs1557052390  rs128624217  rs1557052390  rs1131691916  rs2091709142  rs1131691743  rs2091711094  rs128624218  rs782760033  rs1603232195  rs193922098  rs128624213  rs1131691954  rs797044610  rs1603233120  rs2091726809  rs128624215  rs886044777  rs128624219  rs727503786  rs128624220  rs128624214  rs1569541088  rs128624223  rs398123102  rs128624224  rs1159943880  rs1557054776  rs201568579  rs398123105  rs1557054873  rs398123106  rs128624225  rs201774661  rs78993751  rs1557055260  rs150346282  rs4010613  rs11146842  rs1557055316  rs2091773525  rs1064793877  rs201427153  rs2091773697  rs2091774046  rs1557055340  rs1569541203  rs1557055398  rs1557055405  rs782311214 
Subcellular location [CC]Peroxisome membrane {ECO:0000269|PubMed:10777694, ECO:0000269|PubMed:16946495, ECO:0000269|PubMed:17609205, ECO:0000269|PubMed:18757502, ECO:0000269|PubMed:29397936};
Multi-pass membrane protein {ECO:0000255}. Mitochondrion membrane {ECO:0000269|PubMed:16946495};
Multi-pass membrane protein. Lysosome membrane {ECO:0000269|PubMed:16946495};
Multi-pass membrane protein. Endoplasmic reticulum membrane {ECO:0000269|PubMed:16946495};
Multi-pass membrane protein.
Mouse PG classificationNA
click here to return to the previous page