| Gene Information | |
|---|---|
| Gene Name | ABCB10 |
| Organism | Homo sapiens (Human) |
| Gene Length | 738 |
| Protein Names | ATP-binding cassette sub-family B member 10, mitochondrial (ABC-mitochondrial erythroid protein) (ABC-me protein) (ATP-binding cassette transporter 10) (ABC transporter 10 protein) (Mitochondrial ATP-binding cassette 2) (M-ABC2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000135776 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | Q9NRK6 |
| Gene Card | ABCB10 |
| Uniprot ID | Q9NRK6 |
| Pfam | PF00664; PF00005 |
| In ASD | no |
| Allosteric Prediction | no (-0.973720876) |
| Ortholog in Animals | Alpaca_ ABCB10 ( ortholog_one2one ) Dog_ ABCB10 ( ortholog_one2one ) GuineaPig_ ABCB10 ( ortholog_one2one ) Macaque_ ABCB10 ( ortholog_one2one ) Mouse_ Abcb10 ( ortholog_one2one ) Pig_ ABCB10 ( ortholog_one2one ) Rat_ Abcb10 ( ortholog_one2one ) Rabbit_ ABCB10 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | ABCB6, TAP1, ABCB11, ABCB4, ABCB9, ABCB8, TAP2, ABCB7, ABCB1, ABCB5 |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. Highly expressed in bone marrow, expressed at intermediate to high levels in skeletal muscle, small intestine, thyroid, heart, brain, placenta, liver, pancreas, prostate, testis, ovary, leukocyte, stomach, spinal cord, lymph node, trachea and adrenal gland, and low levels are found in lung, kidney, spleen, thymus and colon. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.066667(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3ZDQ (X-ray 2.85A ) 4AYT (X-ray 2.85A ) 4AYW (X-ray 3.30A ) 4AYX (X-ray 2.90A ) |
| DBSNP | rs4148756 rs17584642 rs35698797 |
| Subcellular location [CC] | Mitochondrion inner membrane {ECO:0000250|UniProtKB:Q9JI39}; Multi-pass membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
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