| Gene Information | |
|---|---|
| Gene Name | PDCL3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 239 |
| Protein Names | Phosducin-like protein 3 (HTPHLP) (PhPL3) (Viral IAP-associated factor 1) (VIAF-1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000115539 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9H2J4 |
| Gene Card | PDCL3 |
| Uniprot ID | Q9H2J4 |
| Pfam | PF02114 |
| In ASD | no |
| Allosteric Prediction | no (-0.339996887) |
| Ortholog in Animals | Alpaca_ PDCL3 ( ortholog_one2one ) GuineaPig_ PDCL3 ( ortholog_one2one ) Mouse_ Pdcl3 ( ortholog_one2one ) Pig_ PDCL3 ( ortholog_one2one ) Rat_ Pdcl3 ( ortholog_one2one ) Rabbit_ PDCL3 ( ortholog_one2one ) |
| Ohnologs | PDCL2 |
| Paralogs | PDC, TXNDC9, PDCL, PDCL2 |
| Tissue | NA |
| Tissue Specificity | Expressed in endothelial cells (at protein level) (PubMed:26059764). Expressed in all tissues examined including spleen, thymus, prostate, testis, ovary, small intestine and colon (PubMed:15371430). {ECO:0000269|PubMed:15371430, ECO:0000269|PubMed:26059764}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.06(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 7NVM (EM 3.10A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:15371430, ECO:0000269|PubMed:26059764}. Cytoplasm, perinuclear region {ECO:0000269|PubMed:26059764}. Endoplasmic reticulum {ECO:0000269|PubMed:26059764}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |