| Gene Information | |
|---|---|
| Gene Name | AASS |
| Organism | Homo sapiens (Human) |
| Gene Length | 926 |
| Protein Names | Alpha-aminoadipic semialdehyde synthase, mitochondrial (LKR/SDH) [Includes: Lysine ketoglutarate reductase (LKR) (LOR) (EC 1.5.1.8); Saccharopine dehydrogenase (SDH) (EC 1.5.1.9)] |
| Target Name | alpha-aminoadipic semialdehyde synthase, mitochondrial |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000008311 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9UDR5 |
| Gene Card | AASS |
| Uniprot ID | Q9UDR5 |
| Pfam | PF01262; PF05222; PF16653; PF03435 |
| In ASD | no |
| Allosteric Prediction | yes (0.210732791) |
| Ortholog in Animals | Alpaca_ AASS ( ortholog_one2one ) Dog_ AASS ( ortholog_one2one ) GuineaPig_ AASS ( ortholog_one2one ) Macaque_ AASS ( ortholog_one2one ) Mouse_ Aass ( ortholog_one2one ) Pig_ AASS ( ortholog_one2one ) Rat_ Aass ( ortholog_one2one ) Rabbit_ AASS ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in all 16 tissues examined with highest expression in the liver. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5L76 (X-ray 2.57A ) 5L78 (X-ray 2.68A ) 5O1N (X-ray 2.28A ) 5O1O (X-ray 2.48A ) 5O1P (X-ray 1.90A ) |
| DBSNP | NA |
| Subcellular location [CC] | Mitochondrion {ECO:0000269|PubMed:463877}. |
| Mouse PG classification | NA |
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