| Gene Information | |
|---|---|
| Gene Name | AARS |
| Organism | Homo sapiens (Human) |
| Gene Length | 968 |
| Protein Names | Alanine--tRNA ligase, cytoplasmic (EC 6.1.1.7) (Alanyl-tRNA synthetase) (AlaRS) (Renal carcinoma antigen NY-REN-42) |
| Target Name | alanine--trna ligase, cytoplasmic |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | P49588 |
| Gene Card | AARS1 |
| Uniprot ID | P49588 |
| Pfam | PF02272; PF01411; PF07973 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001360(Rat);0.007143(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4XEM (X-ray 1.28A ) 4XEO (X-ray 1.38A ) 5KNN (X-ray 2.68A ) 5T5S (X-ray 2.20A ) 5T76 (X-ray 2.00A ) 5V59 (X-ray 2.03A ) |
| DBSNP | rs387906792 rs786205157 rs11537667 rs267606621 rs143370729 rs369774476 |
| Subcellular location [CC] | Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03133, ECO:0000269|PubMed:27911835}. |
| Mouse PG classification | NA |
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