| Gene Information | |
|---|---|
| Gene Name | AANAT |
| Organism | Homo sapiens (Human) |
| Gene Length | 207 |
| Protein Names | Serotonin N-acetyltransferase (Serotonin acetylase) (EC 2.3.1.87) (Aralkylamine N-acetyltransferase) (AA-NAT) |
| Target Name | serotonin n-acetyltransferase |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000129673 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | Q16613 |
| Gene Card | AANAT |
| Uniprot ID | Q16613 |
| Pfam | PF00583 |
| In ASD | no |
| Allosteric Prediction | yes (0.590365594) |
| Ortholog in Animals | Alpaca_ AANAT ( ortholog_one2one ) Dog_ AANAT ( ortholog_one2one ) GuineaPig_ AANAT ( ortholog_one2one ) Macaque_ AANAT ( ortholog_one2one ) Mouse_ Aanat ( ortholog_one2one ) Pig_ AANAT ( ortholog_one2one ) Rat_ Aanat ( ortholog_one2one ) Rabbit_ AANAT ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Highly expressed in pineal gland and at lower levels in the retina. Weak expression in several brain regions and in the pituitary gland. {ECO:0000269|PubMed:18212399, ECO:0000269|PubMed:8661026}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);0.1(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6T80 (X-ray 2.99A ) |
| DBSNP | rs34470791 rs28936679 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:11313340}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |