Gene Information
Gene NameCLNS1A
OrganismHomo sapiens (Human)
Gene Length237
Protein NamesMethylosome subunit pICln (Chloride channel, nucleotide sensitive 1A) (Chloride conductance regulatory protein ICln) (I(Cln)) (Chloride ion current inducer protein) (ClCI) (Reticulocyte pICln)
Target NameNA
Target TypeNA
Gene Age8 ( ENSG00000074201 )
Evolutionary StageEukaryota
AlphaFoldDBP54105
Gene CardCLNS1A
Uniprot IDP54105
PfamPF03517
In ASDno
Allosteric Predictionno (-0.18428133)
Ortholog in AnimalsAlpaca_ CLNS1A ( ortholog_one2one )
Dog_ CLNS1A ( ortholog_one2many )
GuineaPig_ CLNS1A ( ortholog_one2one )
Macaque_ CLNS1A ( ortholog_one2one )
Mouse_ Clns1a ( ortholog_one2one )
Pig_ CLNS1A ( ortholog_one2one )
Rat_ Clns1a ( ortholog_one2many )
Rabbit_ CLNS1A ( ortholog_one2one )
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);0.096227(Rat);0.050000(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 6V0O  (X-ray  2.86A 
DBSNP NA 
Subcellular location [CC]Cytoplasm, cytosol {ECO:0000269|PubMed:18984161, ECO:0000269|PubMed:21081503}. Nucleus {ECO:0000269|PubMed:18984161, ECO:0000269|PubMed:21081503}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:18984161}. Note=A small fraction is also associated with the cytoskeleton (PubMed:18984161).
Mouse PG classificationNA
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