| Gene Information | |
|---|---|
| Gene Name | AADAC |
| Organism | Homo sapiens (Human) |
| Gene Length | 399 |
| Protein Names | Arylacetamide deacetylase (EC 3.1.1.3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000114771 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | P22760 |
| Gene Card | AADAC |
| Uniprot ID | P22760 |
| Pfam | PF07859 |
| In ASD | no |
| Allosteric Prediction | no (-0.235041825) |
| Ortholog in Animals | Alpaca_ AADAC ( ortholog_one2one ) Dog_ AADAC ( ortholog_one2one ) GuineaPig_ AADAC ( ortholog_one2one ) Macaque_ AADAC ( ortholog_one2one ) Mouse_ Aadac ( ortholog_one2one ) Pig_ AADAC ( ortholog_one2one ) Rat_ Aadac ( ortholog_one2one ) Rabbit_ AADAC ( ortholog_one2one ) |
| Ohnologs | AADACL3, AADACL4 |
| Paralogs | NCEH1, AADACL4, AADACL3, AADACL2, AFMID |
| Tissue | adrenal.gland |
| Tissue Specificity | Detected in liver (at protein level). Mainly expressed in liver, small intestine, colon, adrenal gland and bladder. {ECO:0000269|PubMed:19339378, ECO:0000269|PubMed:22207054, ECO:0000269|PubMed:22415931}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs1803155 |
| Subcellular location [CC] | Endoplasmic reticulum membrane; Single-pass type II membrane protein. Microsome membrane; Single-pass type II membrane protein. |
| Mouse PG classification | NA |
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