| Gene Information | |
|---|---|
| Gene Name | POLRMT |
| Organism | Homo sapiens (Human) |
| Gene Length | 1230 |
| Protein Names | DNA-directed RNA polymerase, mitochondrial (MtRPOL) (EC 2.7.7.6) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000099821 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O00411 |
| Gene Card | POLRMT |
| Uniprot ID | O00411 |
| Pfam | PF00940; PF14700 |
| In ASD | yes |
| Allosteric Prediction | no (-0.62538186) |
| Ortholog in Animals | Alpaca_ POLRMT ( ortholog_one2one ) Dog_ POLRMT ( ortholog_one2one ) GuineaPig_ POLRMT ( ortholog_one2one ) Macaque_ POLRMT ( ortholog_one2one ) Mouse_ Polrmt ( ortholog_one2one ) Pig_ POLRMT ( ortholog_one2one ) Rat_ Polrmt ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.005276(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3SPA (X-ray 2.50A ) 4BOC (X-ray 2.65A ) 5OLA (X-ray 3.90A ) 6ERP (X-ray 4.50A ) 6ERQ (X-ray 4.50A ) 7A8P (EM 3.50A ) |
| DBSNP | rs2238549 |
| Subcellular location [CC] | Mitochondrion {ECO:0000269|PubMed:23283301, ECO:0000269|PubMed:29445193}. |
| Mouse PG classification | NA |
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