| Gene Information | |
|---|---|
| Gene Name | 5PTASE |
| Organism | Homo sapiens (Human) |
| Gene Length | 412 |
| Protein Names | Inositol polyphosphate-5-phosphatase A (EC 3.1.3.56) (43 kDa inositol polyphosphate 5-phosphatase) (Type I inositol 1,4,5-trisphosphate 5-phosphatase) (5PTase) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q14642 |
| Gene Card | INPP5A |
| Uniprot ID | Q14642 |
| Pfam | PF03372 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Predominantly expressed in heart, brain, and skeletal muscle (PubMed:8006039). In brain; high level in Purkinje cells (PubMed:8013665). {ECO:0000269|PubMed:8006039, ECO:0000269|PubMed:8013665}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002101(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs1133400 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:8626616, ECO:0000305|PubMed:8006039}; Lipid-anchor {ECO:0000269|PubMed:8626616, ECO:0000305}. Cell projection, dendrite {ECO:0000250|UniProtKB:Q7TNC9}. |
| Mouse PG classification | NA |
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