| Gene Information | |
|---|---|
| Gene Name | 17HSD7 |
| Organism | Homo sapiens (Human) |
| Gene Length | 341 |
| Protein Names | 3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7 (17-beta-hydroxysteroid dehydrogenase 7) (17-beta-HSD 7) (3-keto-steroid reductase) (EC 1.1.1.270) (Dihydrotestosterone oxidoreductase) (EC 1.1.1.210) (Estradiol 17-beta-dehydrogenase 7) (EC 1.1.1.62) (Short chain dehydrogenase/reductase family 37C member 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | P56937 |
| Gene Card | HSD17B7 |
| Uniprot ID | P56937 |
| Pfam | PF00106 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Highly expressed in adrenal gland, liver, lung and thymus. Expressed in breast, ovaries, pituitary gland, pregnant uterus, prostate, kidney, lymph node, small intestine, spinal cord and trachea. Weakly expressed in all other tissues tested. {ECO:0000269|PubMed:12732193}.; [Isoform 3]: Expressed in eye ciliary epithelial cells and neuroendocrine cells. {ECO:0000269|PubMed:12732193}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.04073(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000269|PubMed:12829805}; Single-pass membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
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