| Drug-Target Information | ||||||||
|---|---|---|---|---|---|---|---|---|
| Drug Name | Target Name | Drug Type | Target Type | Source | Drug MeSHID | Interaction Score | Drug Status | Target Action |
| zotepine | d(1) dopamine receptor | small molecule | NA | drugbank | Emotions[MeSHID:D004644] Schizophrenia[MeSHID:D012559] Hallucinations[MeSHID:D006212] Movement Disorders[MeSHID:D009069] Diagnosis[MeSHID:D003933] Delusions[MeSHID:D003702] Affect (mental function)[MeSHID:D000339] Choice Behavior[MeSHID:D002755] Mental Suffering[MeSHID:D013315] Thinking function[MeSHID:D013850] Relapse[MeSHID:D012008] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Anxiety Disorders[MeSHID:D001008] |
NA | approved,investigational,withdrawn | antagonist |
| zotepine | dopamine d2 receptor | small molecule | NA | drugbank , DGIDB | Emotions[MeSHID:D004644] Schizophrenia[MeSHID:D012559] Hallucinations[MeSHID:D006212] Movement Disorders[MeSHID:D009069] Diagnosis[MeSHID:D003933] Delusions[MeSHID:D003702] Affect (mental function)[MeSHID:D000339] Choice Behavior[MeSHID:D002755] Mental Suffering[MeSHID:D013315] Thinking function[MeSHID:D013850] Relapse[MeSHID:D012008] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Anxiety Disorders[MeSHID:D001008] |
0.05 | approved,investigational,withdrawn | antagonist |
| zotepine | d(1) dopamine receptor | small molecule | NA | drugbank | Emotions[MeSHID:D004644] Schizophrenia[MeSHID:D012559] Hallucinations[MeSHID:D006212] Movement Disorders[MeSHID:D009069] Diagnosis[MeSHID:D003933] Delusions[MeSHID:D003702] Affect (mental function)[MeSHID:D000339] Choice Behavior[MeSHID:D002755] Mental Suffering[MeSHID:D013315] Thinking function[MeSHID:D013850] Relapse[MeSHID:D012008] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Anxiety Disorders[MeSHID:D001008] |
NA | approved,investigational,withdrawn | antagonist |
| zotepine | 5-ht 2a receptor | NA | Successful target | TTD , DGIDB | Emotions[MeSHID:D004644] Schizophrenia[MeSHID:D012559] Hallucinations[MeSHID:D006212] Movement Disorders[MeSHID:D009069] Diagnosis[MeSHID:D003933] Delusions[MeSHID:D003702] Affect (mental function)[MeSHID:D000339] Choice Behavior[MeSHID:D002755] Mental Suffering[MeSHID:D013315] Thinking function[MeSHID:D013850] Relapse[MeSHID:D012008] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Anxiety Disorders[MeSHID:D001008] |
0.06 | approved | unknown |
| zotepine | 5-ht 2a receptor | NA | Successful target | TTD , DGIDB | Emotions[MeSHID:D004644] Schizophrenia[MeSHID:D012559] Hallucinations[MeSHID:D006212] Movement Disorders[MeSHID:D009069] Diagnosis[MeSHID:D003933] Delusions[MeSHID:D003702] Affect (mental function)[MeSHID:D000339] Choice Behavior[MeSHID:D002755] Mental Suffering[MeSHID:D013315] Thinking function[MeSHID:D013850] Relapse[MeSHID:D012008] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Anxiety Disorders[MeSHID:D001008] |
0.06 | approved | antagonist |
| zotepine | 5-hydroxytryptamine receptor 2a | small molecule | NA | drugbank , DGIDB | Emotions[MeSHID:D004644] Schizophrenia[MeSHID:D012559] Hallucinations[MeSHID:D006212] Movement Disorders[MeSHID:D009069] Diagnosis[MeSHID:D003933] Delusions[MeSHID:D003702] Affect (mental function)[MeSHID:D000339] Choice Behavior[MeSHID:D002755] Mental Suffering[MeSHID:D013315] Thinking function[MeSHID:D013850] Relapse[MeSHID:D012008] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Anxiety Disorders[MeSHID:D001008] |
0.06 | approved,investigational,withdrawn | antagonist |
| zotepine | 5-hydroxytryptamine receptor 6 | small molecule | NA | drugbank , DGIDB | Emotions[MeSHID:D004644] Schizophrenia[MeSHID:D012559] Hallucinations[MeSHID:D006212] Movement Disorders[MeSHID:D009069] Diagnosis[MeSHID:D003933] Delusions[MeSHID:D003702] Affect (mental function)[MeSHID:D000339] Choice Behavior[MeSHID:D002755] Mental Suffering[MeSHID:D013315] Thinking function[MeSHID:D013850] Relapse[MeSHID:D012008] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Anxiety Disorders[MeSHID:D001008] |
0.1 | approved,investigational,withdrawn | antagonist |
| zotepine | 5-hydroxytryptamine receptor 7 | small molecule | NA | drugbank , DGIDB | Emotions[MeSHID:D004644] Schizophrenia[MeSHID:D012559] Hallucinations[MeSHID:D006212] Movement Disorders[MeSHID:D009069] Diagnosis[MeSHID:D003933] Delusions[MeSHID:D003702] Affect (mental function)[MeSHID:D000339] Choice Behavior[MeSHID:D002755] Mental Suffering[MeSHID:D013315] Thinking function[MeSHID:D013850] Relapse[MeSHID:D012008] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Anxiety Disorders[MeSHID:D001008] |
0.09 | approved,investigational,withdrawn | antagonist |
| zotepine | sodium-dependent noradrenaline transporter | small molecule | NA | drugbank , DGIDB | Emotions[MeSHID:D004644] Schizophrenia[MeSHID:D012559] Hallucinations[MeSHID:D006212] Movement Disorders[MeSHID:D009069] Diagnosis[MeSHID:D003933] Delusions[MeSHID:D003702] Affect (mental function)[MeSHID:D000339] Choice Behavior[MeSHID:D002755] Mental Suffering[MeSHID:D013315] Thinking function[MeSHID:D013850] Relapse[MeSHID:D012008] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Anxiety Disorders[MeSHID:D001008] |
0.09 | approved,investigational,withdrawn | antagonist,inhibitor |
| zotepine | sodium-dependent serotonin transporter | small molecule | NA | drugbank , DGIDB | Emotions[MeSHID:D004644] Schizophrenia[MeSHID:D012559] Hallucinations[MeSHID:D006212] Movement Disorders[MeSHID:D009069] Diagnosis[MeSHID:D003933] Delusions[MeSHID:D003702] Affect (mental function)[MeSHID:D000339] Choice Behavior[MeSHID:D002755] Mental Suffering[MeSHID:D013315] Thinking function[MeSHID:D013850] Relapse[MeSHID:D012008] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Anxiety Disorders[MeSHID:D001008] |
0.07 | approved,investigational,withdrawn | antagonist,inhibitor |
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