| Drug-Target Information | ||||||||
|---|---|---|---|---|---|---|---|---|
| Drug Name | Target Name | Drug Type | Target Type | Source | Drug MeSHID | Interaction Score | Drug Status | Target Action |
| ziprasidone | alpha-1a adrenergic receptor | small molecule | NA | drugbank , DGIDB | Bipolar Disorder[MeSHID:D001714] Schizophrenia[MeSHID:D012559] Maintenance[MeSHID:D008283] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.08 | approved | antagonist |
| ziprasidone | alpha-1b adrenergic receptor | small molecule | NA | drugbank | Bipolar Disorder[MeSHID:D001714] Schizophrenia[MeSHID:D012559] Maintenance[MeSHID:D008283] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | antagonist |
| ziprasidone | alpha-2a adrenergic receptor | small molecule | NA | drugbank | Bipolar Disorder[MeSHID:D001714] Schizophrenia[MeSHID:D012559] Maintenance[MeSHID:D008283] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | antagonist |
| ziprasidone | alpha-2b adrenergic receptor | small molecule | NA | drugbank | Bipolar Disorder[MeSHID:D001714] Schizophrenia[MeSHID:D012559] Maintenance[MeSHID:D008283] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | antagonist |
| ziprasidone | alpha-2c adrenergic receptor | small molecule | NA | drugbank | Bipolar Disorder[MeSHID:D001714] Schizophrenia[MeSHID:D012559] Maintenance[MeSHID:D008283] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | antagonist |
| ziprasidone | muscarinic acetylcholine receptor m1 | small molecule | NA | drugbank | Bipolar Disorder[MeSHID:D001714] Schizophrenia[MeSHID:D012559] Maintenance[MeSHID:D008283] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | antagonist |
| ziprasidone | muscarinic acetylcholine receptor m2 | small molecule | NA | drugbank | Bipolar Disorder[MeSHID:D001714] Schizophrenia[MeSHID:D012559] Maintenance[MeSHID:D008283] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | antagonist |
| ziprasidone | muscarinic acetylcholine receptor m3 | small molecule | NA | drugbank | Bipolar Disorder[MeSHID:D001714] Schizophrenia[MeSHID:D012559] Maintenance[MeSHID:D008283] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | antagonist |
| ziprasidone | muscarinic acetylcholine receptor m4 | small molecule | NA | drugbank | Bipolar Disorder[MeSHID:D001714] Schizophrenia[MeSHID:D012559] Maintenance[MeSHID:D008283] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | antagonist |
| ziprasidone | muscarinic acetylcholine receptor m5 | small molecule | NA | drugbank | Bipolar Disorder[MeSHID:D001714] Schizophrenia[MeSHID:D012559] Maintenance[MeSHID:D008283] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | antagonist |
| ziprasidone | neuronal acetylcholine receptor alpha-7 | NA | Successful target | TTD , DGIDB | Bipolar Disorder[MeSHID:D001714] Schizophrenia[MeSHID:D012559] Maintenance[MeSHID:D008283] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.07 | approved | unknown |
| ziprasidone | dopamine d1 receptor | small molecule | NA | drugbank | Bipolar Disorder[MeSHID:D001714] Schizophrenia[MeSHID:D012559] Maintenance[MeSHID:D008283] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | antagonist |
| ziprasidone | dopamine d2 receptor | small molecule | Successful target | TTD , drugbank , DGIDB | Bipolar Disorder[MeSHID:D001714] Schizophrenia[MeSHID:D012559] Maintenance[MeSHID:D008283] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.17 | approved | antagonist |
| ziprasidone | dopamine d3 receptor | small molecule | NA | drugbank , DGIDB | Bipolar Disorder[MeSHID:D001714] Schizophrenia[MeSHID:D012559] Maintenance[MeSHID:D008283] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.14 | approved | antagonist |
| ziprasidone | dopamine d4 receptor | small molecule | NA | drugbank , DGIDB | Bipolar Disorder[MeSHID:D001714] Schizophrenia[MeSHID:D012559] Maintenance[MeSHID:D008283] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.19 | approved | antagonist |
| ziprasidone | dopamine d5 receptor | small molecule | NA | drugbank | Bipolar Disorder[MeSHID:D001714] Schizophrenia[MeSHID:D012559] Maintenance[MeSHID:D008283] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | antagonist |
| ziprasidone | histamine h1 receptor | small molecule | NA | drugbank , DGIDB | Bipolar Disorder[MeSHID:D001714] Schizophrenia[MeSHID:D012559] Maintenance[MeSHID:D008283] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.1 | approved | antagonist |
| ziprasidone | 5-hydroxytryptamine receptor 1a | small molecule | NA | drugbank , DGIDB | Bipolar Disorder[MeSHID:D001714] Schizophrenia[MeSHID:D012559] Maintenance[MeSHID:D008283] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.29 | approved | agonist |
| ziprasidone | 5-hydroxytryptamine receptor 1b | small molecule | NA | drugbank , DGIDB | Bipolar Disorder[MeSHID:D001714] Schizophrenia[MeSHID:D012559] Maintenance[MeSHID:D008283] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.14 | approved | antagonist,agonist |
| ziprasidone | 5-hydroxytryptamine receptor 1d | small molecule | NA | drugbank , DGIDB | Bipolar Disorder[MeSHID:D001714] Schizophrenia[MeSHID:D012559] Maintenance[MeSHID:D008283] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.4 | approved | antagonist |
| ziprasidone | 5-hydroxytryptamine receptor 1d | small molecule | NA | drugbank , DGIDB | Bipolar Disorder[MeSHID:D001714] Schizophrenia[MeSHID:D012559] Maintenance[MeSHID:D008283] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.4 | approved | antagonist,agonist |
| ziprasidone | 5-hydroxytryptamine receptor 1e | small molecule | NA | drugbank , DGIDB | Bipolar Disorder[MeSHID:D001714] Schizophrenia[MeSHID:D012559] Maintenance[MeSHID:D008283] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.18 | approved | antagonist,agonist |
| ziprasidone | 5-hydroxytryptamine receptor 2a | small molecule | NA | drugbank , DGIDB | Bipolar Disorder[MeSHID:D001714] Schizophrenia[MeSHID:D012559] Maintenance[MeSHID:D008283] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.21 | approved | antagonist |
| ziprasidone | 5-hydroxytryptamine receptor 2c | small molecule | NA | drugbank , DGIDB | Bipolar Disorder[MeSHID:D001714] Schizophrenia[MeSHID:D012559] Maintenance[MeSHID:D008283] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.25 | approved | antagonist |
| ziprasidone | 5-hydroxytryptamine 3 receptor | small molecule | NA | drugbank | Bipolar Disorder[MeSHID:D001714] Schizophrenia[MeSHID:D012559] Maintenance[MeSHID:D008283] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | antagonist |
| ziprasidone | 5-hydroxytryptamine 3 receptor | small molecule | NA | drugbank | Bipolar Disorder[MeSHID:D001714] Schizophrenia[MeSHID:D012559] Maintenance[MeSHID:D008283] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | antagonist |
| ziprasidone | 5-hydroxytryptamine 3 receptor | small molecule | NA | drugbank | Bipolar Disorder[MeSHID:D001714] Schizophrenia[MeSHID:D012559] Maintenance[MeSHID:D008283] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | antagonist |
| ziprasidone | 5-hydroxytryptamine 3 receptor | small molecule | NA | drugbank | Bipolar Disorder[MeSHID:D001714] Schizophrenia[MeSHID:D012559] Maintenance[MeSHID:D008283] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | antagonist |
| ziprasidone | 5-hydroxytryptamine 3 receptor | small molecule | NA | drugbank | Bipolar Disorder[MeSHID:D001714] Schizophrenia[MeSHID:D012559] Maintenance[MeSHID:D008283] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | antagonist |
| ziprasidone | 5-hydroxytryptamine receptor 5a | small molecule | NA | drugbank | Bipolar Disorder[MeSHID:D001714] Schizophrenia[MeSHID:D012559] Maintenance[MeSHID:D008283] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | antagonist |
| ziprasidone | 5-hydroxytryptamine receptor 6 | small molecule | NA | drugbank | Bipolar Disorder[MeSHID:D001714] Schizophrenia[MeSHID:D012559] Maintenance[MeSHID:D008283] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | antagonist |
| ziprasidone | 5-hydroxytryptamine receptor 7 | small molecule | NA | drugbank , DGIDB | Bipolar Disorder[MeSHID:D001714] Schizophrenia[MeSHID:D012559] Maintenance[MeSHID:D008283] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.38 | approved | antagonist |
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