Drug-Target Information
Drug Name Target Name Drug Type Target Type Source Drug MeSHID Interaction Score Drug Status Target Action
xylometazoline alpha-1a adrenergic receptor small molecule NA drugbank Respiratory Hypersensitivity[MeSHID:D012130]
Cold Temperature[MeSHID:D003080]
Hay fever[MeSHID:D006255]
Common Cold[MeSHID:D003139]
Upper Respiratory Infections[MeSHID:D012141]
Nose[MeSHID:D009666]
Allergic rhinitis (disorder)[MeSHID:D065631]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 NA approved,investigational agonist,partial agonist
xylometazoline alpha-1b adrenergic receptor small molecule NA drugbank Respiratory Hypersensitivity[MeSHID:D012130]
Cold Temperature[MeSHID:D003080]
Hay fever[MeSHID:D006255]
Common Cold[MeSHID:D003139]
Upper Respiratory Infections[MeSHID:D012141]
Nose[MeSHID:D009666]
Allergic rhinitis (disorder)[MeSHID:D065631]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 NA approved,investigational agonist
xylometazoline alpha-1d adrenergic receptor small molecule NA drugbank Respiratory Hypersensitivity[MeSHID:D012130]
Cold Temperature[MeSHID:D003080]
Hay fever[MeSHID:D006255]
Common Cold[MeSHID:D003139]
Upper Respiratory Infections[MeSHID:D012141]
Nose[MeSHID:D009666]
Allergic rhinitis (disorder)[MeSHID:D065631]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 NA approved,investigational agonist
xylometazoline alpha-2a adrenergic receptor small molecule NA drugbank Respiratory Hypersensitivity[MeSHID:D012130]
Cold Temperature[MeSHID:D003080]
Hay fever[MeSHID:D006255]
Common Cold[MeSHID:D003139]
Upper Respiratory Infections[MeSHID:D012141]
Nose[MeSHID:D009666]
Allergic rhinitis (disorder)[MeSHID:D065631]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 NA approved,investigational agonist
xylometazoline alpha-2b adrenergic receptor small molecule NA drugbank Respiratory Hypersensitivity[MeSHID:D012130]
Cold Temperature[MeSHID:D003080]
Hay fever[MeSHID:D006255]
Common Cold[MeSHID:D003139]
Upper Respiratory Infections[MeSHID:D012141]
Nose[MeSHID:D009666]
Allergic rhinitis (disorder)[MeSHID:D065631]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 NA approved,investigational agonist
xylometazoline adrenergic receptor alpha-2c NA Successful target TTD , DGIDB Respiratory Hypersensitivity[MeSHID:D012130]
Cold Temperature[MeSHID:D003080]
Hay fever[MeSHID:D006255]
Common Cold[MeSHID:D003139]
Upper Respiratory Infections[MeSHID:D012141]
Nose[MeSHID:D009666]
Allergic rhinitis (disorder)[MeSHID:D065631]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 0.77 phase 4 unknown
xylometazoline alpha-2c adrenergic receptor small molecule NA drugbank , DGIDB Respiratory Hypersensitivity[MeSHID:D012130]
Cold Temperature[MeSHID:D003080]
Hay fever[MeSHID:D006255]
Common Cold[MeSHID:D003139]
Upper Respiratory Infections[MeSHID:D012141]
Nose[MeSHID:D009666]
Allergic rhinitis (disorder)[MeSHID:D065631]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 0.77 approved,investigational agonist
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