| Drug-Target Information | ||||||||
|---|---|---|---|---|---|---|---|---|
| Drug Name | Target Name | Drug Type | Target Type | Source | Drug MeSHID | Interaction Score | Drug Status | Target Action |
| vx-702 | interleukin-1 beta | small molecule | NA | drugbank | Coronary Arteriosclerosis[MeSHID:D003324] Rheumatoid Arthritis[MeSHID:D001172] Disease[MeSHID:D004194] Coronary heart disease[MeSHID:D003327] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Inflammation[MeSHID:D007249] |
NA | investigational | unknown |
| vx-702 | interleukin-6 | small molecule | NA | drugbank | Coronary Arteriosclerosis[MeSHID:D003324] Rheumatoid Arthritis[MeSHID:D001172] Disease[MeSHID:D004194] Coronary heart disease[MeSHID:D003327] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Inflammation[MeSHID:D007249] |
NA | investigational | unknown |
| vx-702 | mitogen-activated protein kinase 14 | small molecule | NA | drugbank , DGIDB | Coronary Arteriosclerosis[MeSHID:D003324] Rheumatoid Arthritis[MeSHID:D001172] Disease[MeSHID:D004194] Coronary heart disease[MeSHID:D003327] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Inflammation[MeSHID:D007249] |
0.49 | investigational | unknown |
| vx-702 | mitogen-activated protein kinase 14 | small molecule | NA | drugbank , DGIDB | Coronary Arteriosclerosis[MeSHID:D003324] Rheumatoid Arthritis[MeSHID:D001172] Disease[MeSHID:D004194] Coronary heart disease[MeSHID:D003327] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Inflammation[MeSHID:D007249] |
0.49 | investigational | inhibitor |
| vx-702 | stress-activated protein kinase 2a | NA | Clinical trial target | TTD , DGIDB | Coronary Arteriosclerosis[MeSHID:D003324] Rheumatoid Arthritis[MeSHID:D001172] Disease[MeSHID:D004194] Coronary heart disease[MeSHID:D003327] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Inflammation[MeSHID:D007249] |
0.49 | phase 2a | unknown |
| vx-702 | stress-activated protein kinase 2a | NA | Clinical trial target | TTD , DGIDB | Coronary Arteriosclerosis[MeSHID:D003324] Rheumatoid Arthritis[MeSHID:D001172] Disease[MeSHID:D004194] Coronary heart disease[MeSHID:D003327] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Inflammation[MeSHID:D007249] |
0.49 | phase 2a | inhibitor |
| vx-702 | tumor necrosis factor | small molecule | NA | drugbank | Coronary Arteriosclerosis[MeSHID:D003324] Rheumatoid Arthritis[MeSHID:D001172] Disease[MeSHID:D004194] Coronary heart disease[MeSHID:D003327] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Inflammation[MeSHID:D007249] |
NA | investigational | unknown |
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