Drug-Target Information
Drug Name Target Name Drug Type Target Type Source Drug MeSHID Interaction Score Drug Status Target Action
verapamil alpha-1a adrenergic receptor small molecule NA drugbank Hypertensive disease[MeSHID:D006973]
Tachyarrhythmia[MeSHID:D013610]
Atrial Flutter[MeSHID:D001282]
Angina
Unstable[MeSHID:D000789]
Cluster Headache[MeSHID:D003027]
Supraventricular tachycardia[MeSHID:D013617]
Stable angina[MeSHID:D060050]
Heart Ventricle[MeSHID:D006352]
Atrial Fibrillation[MeSHID:D001281]
Off-Label Use[MeSHID:D056687]
Angina Pectoris
Variant[MeSHID:D000788]
pathologic fistula[MeSHID:D005402]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 NA approved antagonist
verapamil alpha-1a adrenergic receptor small molecule NA drugbank Hypertensive disease[MeSHID:D006973]
Tachyarrhythmia[MeSHID:D013610]
Atrial Flutter[MeSHID:D001282]
Angina
Unstable[MeSHID:D000789]
Cluster Headache[MeSHID:D003027]
Supraventricular tachycardia[MeSHID:D013617]
Stable angina[MeSHID:D060050]
Heart Ventricle[MeSHID:D006352]
Atrial Fibrillation[MeSHID:D001281]
Off-Label Use[MeSHID:D056687]
Angina Pectoris
Variant[MeSHID:D000788]
pathologic fistula[MeSHID:D005402]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Coronavirus Infections[MeSHID:D018352]
Disease[MeSHID:D004194]		 NA approved antagonist
verapamil alpha-1b adrenergic receptor small molecule NA drugbank Hypertensive disease[MeSHID:D006973]
Tachyarrhythmia[MeSHID:D013610]
Atrial Flutter[MeSHID:D001282]
Angina
Unstable[MeSHID:D000789]
Cluster Headache[MeSHID:D003027]
Supraventricular tachycardia[MeSHID:D013617]
Stable angina[MeSHID:D060050]
Heart Ventricle[MeSHID:D006352]
Atrial Fibrillation[MeSHID:D001281]
Off-Label Use[MeSHID:D056687]
Angina Pectoris
Variant[MeSHID:D000788]
pathologic fistula[MeSHID:D005402]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 NA approved antagonist
verapamil alpha-1b adrenergic receptor small molecule NA drugbank Hypertensive disease[MeSHID:D006973]
Tachyarrhythmia[MeSHID:D013610]
Atrial Flutter[MeSHID:D001282]
Angina
Unstable[MeSHID:D000789]
Cluster Headache[MeSHID:D003027]
Supraventricular tachycardia[MeSHID:D013617]
Stable angina[MeSHID:D060050]
Heart Ventricle[MeSHID:D006352]
Atrial Fibrillation[MeSHID:D001281]
Off-Label Use[MeSHID:D056687]
Angina Pectoris
Variant[MeSHID:D000788]
pathologic fistula[MeSHID:D005402]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Coronavirus Infections[MeSHID:D018352]
Disease[MeSHID:D004194]		 NA approved antagonist
verapamil alpha-1d adrenergic receptor small molecule NA drugbank Hypertensive disease[MeSHID:D006973]
Tachyarrhythmia[MeSHID:D013610]
Atrial Flutter[MeSHID:D001282]
Angina
Unstable[MeSHID:D000789]
Cluster Headache[MeSHID:D003027]
Supraventricular tachycardia[MeSHID:D013617]
Stable angina[MeSHID:D060050]
Heart Ventricle[MeSHID:D006352]
Atrial Fibrillation[MeSHID:D001281]
Off-Label Use[MeSHID:D056687]
Angina Pectoris
Variant[MeSHID:D000788]
pathologic fistula[MeSHID:D005402]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 NA approved antagonist
verapamil alpha-1d adrenergic receptor small molecule NA drugbank Hypertensive disease[MeSHID:D006973]
Tachyarrhythmia[MeSHID:D013610]
Atrial Flutter[MeSHID:D001282]
Angina
Unstable[MeSHID:D000789]
Cluster Headache[MeSHID:D003027]
Supraventricular tachycardia[MeSHID:D013617]
Stable angina[MeSHID:D060050]
Heart Ventricle[MeSHID:D006352]
Atrial Fibrillation[MeSHID:D001281]
Off-Label Use[MeSHID:D056687]
Angina Pectoris
Variant[MeSHID:D000788]
pathologic fistula[MeSHID:D005402]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Coronavirus Infections[MeSHID:D018352]
Disease[MeSHID:D004194]		 NA approved antagonist
verapamil voltage-dependent p/q-type calcium channel subunit alpha-1a small molecule NA drugbank Hypertensive disease[MeSHID:D006973]
Tachyarrhythmia[MeSHID:D013610]
Atrial Flutter[MeSHID:D001282]
Angina
Unstable[MeSHID:D000789]
Cluster Headache[MeSHID:D003027]
Supraventricular tachycardia[MeSHID:D013617]
Stable angina[MeSHID:D060050]
Heart Ventricle[MeSHID:D006352]
Atrial Fibrillation[MeSHID:D001281]
Off-Label Use[MeSHID:D056687]
Angina Pectoris
Variant[MeSHID:D000788]
pathologic fistula[MeSHID:D005402]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 NA approved inhibitor
verapamil voltage-dependent p/q-type calcium channel subunit alpha-1a small molecule NA drugbank Hypertensive disease[MeSHID:D006973]
Tachyarrhythmia[MeSHID:D013610]
Atrial Flutter[MeSHID:D001282]
Angina
Unstable[MeSHID:D000789]
Cluster Headache[MeSHID:D003027]
Supraventricular tachycardia[MeSHID:D013617]
Stable angina[MeSHID:D060050]
Heart Ventricle[MeSHID:D006352]
Atrial Fibrillation[MeSHID:D001281]
Off-Label Use[MeSHID:D056687]
Angina Pectoris
Variant[MeSHID:D000788]
pathologic fistula[MeSHID:D005402]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Coronavirus Infections[MeSHID:D018352]
Disease[MeSHID:D004194]		 NA approved inhibitor
verapamil voltage-dependent n-type calcium channel subunit alpha-1b small molecule NA drugbank Hypertensive disease[MeSHID:D006973]
Tachyarrhythmia[MeSHID:D013610]
Atrial Flutter[MeSHID:D001282]
Angina
Unstable[MeSHID:D000789]
Cluster Headache[MeSHID:D003027]
Supraventricular tachycardia[MeSHID:D013617]
Stable angina[MeSHID:D060050]
Heart Ventricle[MeSHID:D006352]
Atrial Fibrillation[MeSHID:D001281]
Off-Label Use[MeSHID:D056687]
Angina Pectoris
Variant[MeSHID:D000788]
pathologic fistula[MeSHID:D005402]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 NA approved inhibitor
verapamil voltage-dependent n-type calcium channel subunit alpha-1b small molecule NA drugbank Hypertensive disease[MeSHID:D006973]
Tachyarrhythmia[MeSHID:D013610]
Atrial Flutter[MeSHID:D001282]
Angina
Unstable[MeSHID:D000789]
Cluster Headache[MeSHID:D003027]
Supraventricular tachycardia[MeSHID:D013617]
Stable angina[MeSHID:D060050]
Heart Ventricle[MeSHID:D006352]
Atrial Fibrillation[MeSHID:D001281]
Off-Label Use[MeSHID:D056687]
Angina Pectoris
Variant[MeSHID:D000788]
pathologic fistula[MeSHID:D005402]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Coronavirus Infections[MeSHID:D018352]
Disease[MeSHID:D004194]		 NA approved inhibitor
verapamil voltage-dependent l-type calcium channel subunit alpha-1c small molecule NA drugbank , DGIDB Hypertensive disease[MeSHID:D006973]
Tachyarrhythmia[MeSHID:D013610]
Atrial Flutter[MeSHID:D001282]
Angina
Unstable[MeSHID:D000789]
Cluster Headache[MeSHID:D003027]
Supraventricular tachycardia[MeSHID:D013617]
Stable angina[MeSHID:D060050]
Heart Ventricle[MeSHID:D006352]
Atrial Fibrillation[MeSHID:D001281]
Off-Label Use[MeSHID:D056687]
Angina Pectoris
Variant[MeSHID:D000788]
pathologic fistula[MeSHID:D005402]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 0.42 approved inhibitor,blocker
verapamil voltage-dependent l-type calcium channel subunit alpha-1c small molecule NA drugbank , DGIDB Hypertensive disease[MeSHID:D006973]
Tachyarrhythmia[MeSHID:D013610]
Atrial Flutter[MeSHID:D001282]
Angina
Unstable[MeSHID:D000789]
Cluster Headache[MeSHID:D003027]
Supraventricular tachycardia[MeSHID:D013617]
Stable angina[MeSHID:D060050]
Heart Ventricle[MeSHID:D006352]
Atrial Fibrillation[MeSHID:D001281]
Off-Label Use[MeSHID:D056687]
Angina Pectoris
Variant[MeSHID:D000788]
pathologic fistula[MeSHID:D005402]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Coronavirus Infections[MeSHID:D018352]
Disease[MeSHID:D004194]		 0.42 approved inhibitor
verapamil voltage-dependent l-type calcium channel subunit alpha-1c small molecule NA drugbank , DGIDB Hypertensive disease[MeSHID:D006973]
Tachyarrhythmia[MeSHID:D013610]
Atrial Flutter[MeSHID:D001282]
Angina
Unstable[MeSHID:D000789]
Cluster Headache[MeSHID:D003027]
Supraventricular tachycardia[MeSHID:D013617]
Stable angina[MeSHID:D060050]
Heart Ventricle[MeSHID:D006352]
Atrial Fibrillation[MeSHID:D001281]
Off-Label Use[MeSHID:D056687]
Angina Pectoris
Variant[MeSHID:D000788]
pathologic fistula[MeSHID:D005402]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Coronavirus Infections[MeSHID:D018352]
Disease[MeSHID:D004194]		 0.42 approved inhibitor,blocker
verapamil voltage-dependent l-type calcium channel subunit alpha-1c small molecule NA drugbank , DGIDB Hypertensive disease[MeSHID:D006973]
Tachyarrhythmia[MeSHID:D013610]
Atrial Flutter[MeSHID:D001282]
Angina
Unstable[MeSHID:D000789]
Cluster Headache[MeSHID:D003027]
Supraventricular tachycardia[MeSHID:D013617]
Stable angina[MeSHID:D060050]
Heart Ventricle[MeSHID:D006352]
Atrial Fibrillation[MeSHID:D001281]
Off-Label Use[MeSHID:D056687]
Angina Pectoris
Variant[MeSHID:D000788]
pathologic fistula[MeSHID:D005402]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 0.42 approved inhibitor
verapamil voltage-dependent t-type calcium channel subunit alpha-1g small molecule NA drugbank , DGIDB Hypertensive disease[MeSHID:D006973]
Tachyarrhythmia[MeSHID:D013610]
Atrial Flutter[MeSHID:D001282]
Angina
Unstable[MeSHID:D000789]
Cluster Headache[MeSHID:D003027]
Supraventricular tachycardia[MeSHID:D013617]
Stable angina[MeSHID:D060050]
Heart Ventricle[MeSHID:D006352]
Atrial Fibrillation[MeSHID:D001281]
Off-Label Use[MeSHID:D056687]
Angina Pectoris
Variant[MeSHID:D000788]
pathologic fistula[MeSHID:D005402]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 0.48 approved inhibitor
verapamil voltage-dependent t-type calcium channel subunit alpha-1g small molecule NA drugbank , DGIDB Hypertensive disease[MeSHID:D006973]
Tachyarrhythmia[MeSHID:D013610]
Atrial Flutter[MeSHID:D001282]
Angina
Unstable[MeSHID:D000789]
Cluster Headache[MeSHID:D003027]
Supraventricular tachycardia[MeSHID:D013617]
Stable angina[MeSHID:D060050]
Heart Ventricle[MeSHID:D006352]
Atrial Fibrillation[MeSHID:D001281]
Off-Label Use[MeSHID:D056687]
Angina Pectoris
Variant[MeSHID:D000788]
pathologic fistula[MeSHID:D005402]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Coronavirus Infections[MeSHID:D018352]
Disease[MeSHID:D004194]		 0.48 approved inhibitor
verapamil voltage-gated calcium channel alpha cav3.1 NA Successful target TTD , DGIDB Hypertensive disease[MeSHID:D006973]
Tachyarrhythmia[MeSHID:D013610]
Atrial Flutter[MeSHID:D001282]
Angina
Unstable[MeSHID:D000789]
Cluster Headache[MeSHID:D003027]
Supraventricular tachycardia[MeSHID:D013617]
Stable angina[MeSHID:D060050]
Heart Ventricle[MeSHID:D006352]
Atrial Fibrillation[MeSHID:D001281]
Off-Label Use[MeSHID:D056687]
Angina Pectoris
Variant[MeSHID:D000788]
pathologic fistula[MeSHID:D005402]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Coronavirus Infections[MeSHID:D018352]
Disease[MeSHID:D004194]		 0.48 approved unknown
verapamil voltage-gated calcium channel alpha cav3.1 NA Successful target TTD , DGIDB Hypertensive disease[MeSHID:D006973]
Tachyarrhythmia[MeSHID:D013610]
Atrial Flutter[MeSHID:D001282]
Angina
Unstable[MeSHID:D000789]
Cluster Headache[MeSHID:D003027]
Supraventricular tachycardia[MeSHID:D013617]
Stable angina[MeSHID:D060050]
Heart Ventricle[MeSHID:D006352]
Atrial Fibrillation[MeSHID:D001281]
Off-Label Use[MeSHID:D056687]
Angina Pectoris
Variant[MeSHID:D000788]
pathologic fistula[MeSHID:D005402]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 0.48 approved unknown
verapamil voltage-dependent t-type calcium channel subunit alpha-1h small molecule NA drugbank Hypertensive disease[MeSHID:D006973]
Tachyarrhythmia[MeSHID:D013610]
Atrial Flutter[MeSHID:D001282]
Angina
Unstable[MeSHID:D000789]
Cluster Headache[MeSHID:D003027]
Supraventricular tachycardia[MeSHID:D013617]
Stable angina[MeSHID:D060050]
Heart Ventricle[MeSHID:D006352]
Atrial Fibrillation[MeSHID:D001281]
Off-Label Use[MeSHID:D056687]
Angina Pectoris
Variant[MeSHID:D000788]
pathologic fistula[MeSHID:D005402]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Coronavirus Infections[MeSHID:D018352]
Disease[MeSHID:D004194]		 NA approved inhibitor
verapamil voltage-dependent t-type calcium channel subunit alpha-1h small molecule NA drugbank Hypertensive disease[MeSHID:D006973]
Tachyarrhythmia[MeSHID:D013610]
Atrial Flutter[MeSHID:D001282]
Angina
Unstable[MeSHID:D000789]
Cluster Headache[MeSHID:D003027]
Supraventricular tachycardia[MeSHID:D013617]
Stable angina[MeSHID:D060050]
Heart Ventricle[MeSHID:D006352]
Atrial Fibrillation[MeSHID:D001281]
Off-Label Use[MeSHID:D056687]
Angina Pectoris
Variant[MeSHID:D000788]
pathologic fistula[MeSHID:D005402]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 NA approved inhibitor
verapamil potassium voltage-gated channel subfamily h member 2 small molecule NA drugbank Hypertensive disease[MeSHID:D006973]
Tachyarrhythmia[MeSHID:D013610]
Atrial Flutter[MeSHID:D001282]
Angina
Unstable[MeSHID:D000789]
Cluster Headache[MeSHID:D003027]
Supraventricular tachycardia[MeSHID:D013617]
Stable angina[MeSHID:D060050]
Heart Ventricle[MeSHID:D006352]
Atrial Fibrillation[MeSHID:D001281]
Off-Label Use[MeSHID:D056687]
Angina Pectoris
Variant[MeSHID:D000788]
pathologic fistula[MeSHID:D005402]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 NA approved inhibitor
verapamil potassium voltage-gated channel subfamily h member 2 small molecule NA drugbank Hypertensive disease[MeSHID:D006973]
Tachyarrhythmia[MeSHID:D013610]
Atrial Flutter[MeSHID:D001282]
Angina
Unstable[MeSHID:D000789]
Cluster Headache[MeSHID:D003027]
Supraventricular tachycardia[MeSHID:D013617]
Stable angina[MeSHID:D060050]
Heart Ventricle[MeSHID:D006352]
Atrial Fibrillation[MeSHID:D001281]
Off-Label Use[MeSHID:D056687]
Angina Pectoris
Variant[MeSHID:D000788]
pathologic fistula[MeSHID:D005402]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Coronavirus Infections[MeSHID:D018352]
Disease[MeSHID:D004194]		 NA approved inhibitor
verapamil atp-sensitive inward rectifier potassium channel 11 small molecule NA drugbank Hypertensive disease[MeSHID:D006973]
Tachyarrhythmia[MeSHID:D013610]
Atrial Flutter[MeSHID:D001282]
Angina
Unstable[MeSHID:D000789]
Cluster Headache[MeSHID:D003027]
Supraventricular tachycardia[MeSHID:D013617]
Stable angina[MeSHID:D060050]
Heart Ventricle[MeSHID:D006352]
Atrial Fibrillation[MeSHID:D001281]
Off-Label Use[MeSHID:D056687]
Angina Pectoris
Variant[MeSHID:D000788]
pathologic fistula[MeSHID:D005402]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 NA approved inhibitor
verapamil atp-sensitive inward rectifier potassium channel 11 small molecule NA drugbank Hypertensive disease[MeSHID:D006973]
Tachyarrhythmia[MeSHID:D013610]
Atrial Flutter[MeSHID:D001282]
Angina
Unstable[MeSHID:D000789]
Cluster Headache[MeSHID:D003027]
Supraventricular tachycardia[MeSHID:D013617]
Stable angina[MeSHID:D060050]
Heart Ventricle[MeSHID:D006352]
Atrial Fibrillation[MeSHID:D001281]
Off-Label Use[MeSHID:D056687]
Angina Pectoris
Variant[MeSHID:D000788]
pathologic fistula[MeSHID:D005402]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Coronavirus Infections[MeSHID:D018352]
Disease[MeSHID:D004194]		 NA approved inhibitor
verapamil sodium-dependent serotonin transporter small molecule NA drugbank Hypertensive disease[MeSHID:D006973]
Tachyarrhythmia[MeSHID:D013610]
Atrial Flutter[MeSHID:D001282]
Angina
Unstable[MeSHID:D000789]
Cluster Headache[MeSHID:D003027]
Supraventricular tachycardia[MeSHID:D013617]
Stable angina[MeSHID:D060050]
Heart Ventricle[MeSHID:D006352]
Atrial Fibrillation[MeSHID:D001281]
Off-Label Use[MeSHID:D056687]
Angina Pectoris
Variant[MeSHID:D000788]
pathologic fistula[MeSHID:D005402]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Coronavirus Infections[MeSHID:D018352]
Disease[MeSHID:D004194]		 NA approved unknown
verapamil sodium-dependent serotonin transporter small molecule NA drugbank Hypertensive disease[MeSHID:D006973]
Tachyarrhythmia[MeSHID:D013610]
Atrial Flutter[MeSHID:D001282]
Angina
Unstable[MeSHID:D000789]
Cluster Headache[MeSHID:D003027]
Supraventricular tachycardia[MeSHID:D013617]
Stable angina[MeSHID:D060050]
Heart Ventricle[MeSHID:D006352]
Atrial Fibrillation[MeSHID:D001281]
Off-Label Use[MeSHID:D056687]
Angina Pectoris
Variant[MeSHID:D000788]
pathologic fistula[MeSHID:D005402]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 NA approved unknown
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