Drug-Target Information
Drug Name Target Name Drug Type Target Type Source Drug MeSHID Interaction Score Drug Status Target Action
varenicline neuronal acetylcholine receptor subunit alpha-3 small molecule NA drugbank , DGIDB Cessation of smoking[MeSHID:D016540]
Nose[MeSHID:D009666]
Disorder of eye[MeSHID:D005128]
Desiccation[MeSHID:D003890]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
emotional dependency[MeSHID:D003858]
Smoking[MeSHID:D012907]
Tobacco smoking behavior[MeSHID:D000073869]		 1.36 approved,investigational partial agonist
varenicline neuronal acetylcholine receptor subunit alpha-3 small molecule NA drugbank , DGIDB Cessation of smoking[MeSHID:D016540]
Nose[MeSHID:D009666]
Disorder of eye[MeSHID:D005128]
Desiccation[MeSHID:D003890]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
emotional dependency[MeSHID:D003858]
Smoking[MeSHID:D012907]
Tobacco smoking behavior[MeSHID:D000073869]		 1.36 approved,investigational partial agonist,agonist
varenicline neuronal acetylcholine receptor subunit alpha-4 small molecule NA drugbank , DGIDB Cessation of smoking[MeSHID:D016540]
Nose[MeSHID:D009666]
Disorder of eye[MeSHID:D005128]
Desiccation[MeSHID:D003890]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
emotional dependency[MeSHID:D003858]
Smoking[MeSHID:D012907]
Tobacco smoking behavior[MeSHID:D000073869]		 2.22 approved,investigational partial agonist
varenicline neuronal acetylcholine receptor subunit alpha-4 small molecule NA drugbank , DGIDB Cessation of smoking[MeSHID:D016540]
Nose[MeSHID:D009666]
Disorder of eye[MeSHID:D005128]
Desiccation[MeSHID:D003890]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
emotional dependency[MeSHID:D003858]
Smoking[MeSHID:D012907]
Tobacco smoking behavior[MeSHID:D000073869]		 2.22 approved,investigational partial agonist,agonist
varenicline neuronal acetylcholine receptor subunit alpha-6 small molecule NA drugbank Cessation of smoking[MeSHID:D016540]
Nose[MeSHID:D009666]
Disorder of eye[MeSHID:D005128]
Desiccation[MeSHID:D003890]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
emotional dependency[MeSHID:D003858]
Smoking[MeSHID:D012907]
Tobacco smoking behavior[MeSHID:D000073869]		 NA approved,investigational partial agonist
varenicline neuronal acetylcholine receptor subunit alpha-7 small molecule NA drugbank , DGIDB Cessation of smoking[MeSHID:D016540]
Nose[MeSHID:D009666]
Disorder of eye[MeSHID:D005128]
Desiccation[MeSHID:D003890]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
emotional dependency[MeSHID:D003858]
Smoking[MeSHID:D012907]
Tobacco smoking behavior[MeSHID:D000073869]		 0.62 approved,investigational agonist
varenicline neuronal acetylcholine receptor subunit beta-2 small molecule NA drugbank , DGIDB Cessation of smoking[MeSHID:D016540]
Nose[MeSHID:D009666]
Disorder of eye[MeSHID:D005128]
Desiccation[MeSHID:D003890]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
emotional dependency[MeSHID:D003858]
Smoking[MeSHID:D012907]
Tobacco smoking behavior[MeSHID:D000073869]		 1.14 approved,investigational partial agonist
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