| Drug-Target Information | ||||||||
|---|---|---|---|---|---|---|---|---|
| Drug Name | Target Name | Drug Type | Target Type | Source | Drug MeSHID | Interaction Score | Drug Status | Target Action |
| valproic acid | short/branched chain specific acyl-coa dehydrogenase, mitochondrial | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Bipolar Disorder[MeSHID:D001714] Maintenance[MeSHID:D008283] Status Epilepticus[MeSHID:D013226] Absence Epilepsy[MeSHID:D004832] Seizures Focal[MeSHID:D012640] Migraine Disorders[MeSHID:D008881] Disease[MeSHID:D004194] Coronavirus Infections[MeSHID:D018352] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | inhibitor |
| valproic acid | succinate-semialdehyde dehydrogenase, mitochondrial | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Bipolar Disorder[MeSHID:D001714] Maintenance[MeSHID:D008283] Status Epilepticus[MeSHID:D013226] Absence Epilepsy[MeSHID:D004832] Seizures Focal[MeSHID:D012640] Migraine Disorders[MeSHID:D008881] Disease[MeSHID:D004194] Coronavirus Infections[MeSHID:D018352] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
1.77 | approved,investigational | inhibitor |
| valproic acid | succinate-semialdehyde dehydrogenase, mitochondrial | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Bipolar Disorder[MeSHID:D001714] Maintenance[MeSHID:D008283] Status Epilepticus[MeSHID:D013226] Absence Epilepsy[MeSHID:D004832] Seizures Focal[MeSHID:D012640] Migraine Disorders[MeSHID:D008881] Disease[MeSHID:D004194] Coronavirus Infections[MeSHID:D018352] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | inhibitor |
| valproic acid | histone deacetylase 2 | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Bipolar Disorder[MeSHID:D001714] Maintenance[MeSHID:D008283] Status Epilepticus[MeSHID:D013226] Absence Epilepsy[MeSHID:D004832] Seizures Focal[MeSHID:D012640] Migraine Disorders[MeSHID:D008881] Disease[MeSHID:D004194] Coronavirus Infections[MeSHID:D018352] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.19 | approved,investigational | inhibitor |
| valproic acid | histone deacetylase 2 | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Bipolar Disorder[MeSHID:D001714] Maintenance[MeSHID:D008283] Status Epilepticus[MeSHID:D013226] Absence Epilepsy[MeSHID:D004832] Seizures Focal[MeSHID:D012640] Migraine Disorders[MeSHID:D008881] Disease[MeSHID:D004194] Coronavirus Infections[MeSHID:D018352] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.33 | approved,investigational | inhibitor |
| valproic acid | histone deacetylase 9 | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Bipolar Disorder[MeSHID:D001714] Maintenance[MeSHID:D008283] Status Epilepticus[MeSHID:D013226] Absence Epilepsy[MeSHID:D004832] Seizures Focal[MeSHID:D012640] Migraine Disorders[MeSHID:D008881] Disease[MeSHID:D004194] Coronavirus Infections[MeSHID:D018352] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | inhibitor |
| valproic acid | histone deacetylase 9 | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Bipolar Disorder[MeSHID:D001714] Maintenance[MeSHID:D008283] Status Epilepticus[MeSHID:D013226] Absence Epilepsy[MeSHID:D004832] Seizures Focal[MeSHID:D012640] Migraine Disorders[MeSHID:D008881] Disease[MeSHID:D004194] Coronavirus Infections[MeSHID:D018352] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.23 | approved,investigational | inhibitor |
| valproic acid | histone deacetylase 9 | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Bipolar Disorder[MeSHID:D001714] Maintenance[MeSHID:D008283] Status Epilepticus[MeSHID:D013226] Absence Epilepsy[MeSHID:D004832] Seizures Focal[MeSHID:D012640] Migraine Disorders[MeSHID:D008881] Disease[MeSHID:D004194] Coronavirus Infections[MeSHID:D018352] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.42 | approved,investigational | inhibitor |
| valproic acid | 2-oxoglutarate dehydrogenase, mitochondrial | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Bipolar Disorder[MeSHID:D001714] Maintenance[MeSHID:D008283] Status Epilepticus[MeSHID:D013226] Absence Epilepsy[MeSHID:D004832] Seizures Focal[MeSHID:D012640] Migraine Disorders[MeSHID:D008881] Disease[MeSHID:D004194] Coronavirus Infections[MeSHID:D018352] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | inhibitor |
| valproic acid | peroxisome proliferator-activated receptor alpha | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Bipolar Disorder[MeSHID:D001714] Maintenance[MeSHID:D008283] Status Epilepticus[MeSHID:D013226] Absence Epilepsy[MeSHID:D004832] Seizures Focal[MeSHID:D012640] Migraine Disorders[MeSHID:D008881] Disease[MeSHID:D004194] Coronavirus Infections[MeSHID:D018352] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | unknown |
| valproic acid | peroxisome proliferator-activated receptor delta | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Bipolar Disorder[MeSHID:D001714] Maintenance[MeSHID:D008283] Status Epilepticus[MeSHID:D013226] Absence Epilepsy[MeSHID:D004832] Seizures Focal[MeSHID:D012640] Migraine Disorders[MeSHID:D008881] Disease[MeSHID:D004194] Coronavirus Infections[MeSHID:D018352] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | unknown |
| valproic acid | peroxisome proliferator-activated receptor gamma | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Bipolar Disorder[MeSHID:D001714] Maintenance[MeSHID:D008283] Status Epilepticus[MeSHID:D013226] Absence Epilepsy[MeSHID:D004832] Seizures Focal[MeSHID:D012640] Migraine Disorders[MeSHID:D008881] Disease[MeSHID:D004194] Coronavirus Infections[MeSHID:D018352] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | unknown |
| valproic acid | sodium channel protein | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Bipolar Disorder[MeSHID:D001714] Maintenance[MeSHID:D008283] Status Epilepticus[MeSHID:D013226] Absence Epilepsy[MeSHID:D004832] Seizures Focal[MeSHID:D012640] Migraine Disorders[MeSHID:D008881] Disease[MeSHID:D004194] Coronavirus Infections[MeSHID:D018352] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | inhibitor |
| valproic acid | sodium channel protein | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Bipolar Disorder[MeSHID:D001714] Maintenance[MeSHID:D008283] Status Epilepticus[MeSHID:D013226] Absence Epilepsy[MeSHID:D004832] Seizures Focal[MeSHID:D012640] Migraine Disorders[MeSHID:D008881] Disease[MeSHID:D004194] Coronavirus Infections[MeSHID:D018352] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | inhibitor |
| valproic acid | sodium channel protein | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Bipolar Disorder[MeSHID:D001714] Maintenance[MeSHID:D008283] Status Epilepticus[MeSHID:D013226] Absence Epilepsy[MeSHID:D004832] Seizures Focal[MeSHID:D012640] Migraine Disorders[MeSHID:D008881] Disease[MeSHID:D004194] Coronavirus Infections[MeSHID:D018352] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | inhibitor |
| valproic acid | sodium channel protein | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Bipolar Disorder[MeSHID:D001714] Maintenance[MeSHID:D008283] Status Epilepticus[MeSHID:D013226] Absence Epilepsy[MeSHID:D004832] Seizures Focal[MeSHID:D012640] Migraine Disorders[MeSHID:D008881] Disease[MeSHID:D004194] Coronavirus Infections[MeSHID:D018352] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | inhibitor |
| valproic acid | sodium channel protein | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Bipolar Disorder[MeSHID:D001714] Maintenance[MeSHID:D008283] Status Epilepticus[MeSHID:D013226] Absence Epilepsy[MeSHID:D004832] Seizures Focal[MeSHID:D012640] Migraine Disorders[MeSHID:D008881] Disease[MeSHID:D004194] Coronavirus Infections[MeSHID:D018352] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | inhibitor |
| valproic acid | sodium channel protein | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Bipolar Disorder[MeSHID:D001714] Maintenance[MeSHID:D008283] Status Epilepticus[MeSHID:D013226] Absence Epilepsy[MeSHID:D004832] Seizures Focal[MeSHID:D012640] Migraine Disorders[MeSHID:D008881] Disease[MeSHID:D004194] Coronavirus Infections[MeSHID:D018352] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | inhibitor |
| valproic acid | sodium channel protein | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Bipolar Disorder[MeSHID:D001714] Maintenance[MeSHID:D008283] Status Epilepticus[MeSHID:D013226] Absence Epilepsy[MeSHID:D004832] Seizures Focal[MeSHID:D012640] Migraine Disorders[MeSHID:D008881] Disease[MeSHID:D004194] Coronavirus Infections[MeSHID:D018352] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | inhibitor |
| valproic acid | sodium channel protein | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Bipolar Disorder[MeSHID:D001714] Maintenance[MeSHID:D008283] Status Epilepticus[MeSHID:D013226] Absence Epilepsy[MeSHID:D004832] Seizures Focal[MeSHID:D012640] Migraine Disorders[MeSHID:D008881] Disease[MeSHID:D004194] Coronavirus Infections[MeSHID:D018352] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | inhibitor |
| valproic acid | sodium channel protein | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Bipolar Disorder[MeSHID:D001714] Maintenance[MeSHID:D008283] Status Epilepticus[MeSHID:D013226] Absence Epilepsy[MeSHID:D004832] Seizures Focal[MeSHID:D012640] Migraine Disorders[MeSHID:D008881] Disease[MeSHID:D004194] Coronavirus Infections[MeSHID:D018352] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | inhibitor |
| valproic acid | sodium channel protein | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Bipolar Disorder[MeSHID:D001714] Maintenance[MeSHID:D008283] Status Epilepticus[MeSHID:D013226] Absence Epilepsy[MeSHID:D004832] Seizures Focal[MeSHID:D012640] Migraine Disorders[MeSHID:D008881] Disease[MeSHID:D004194] Coronavirus Infections[MeSHID:D018352] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | inhibitor |
| valproic acid | sodium channel protein | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Bipolar Disorder[MeSHID:D001714] Maintenance[MeSHID:D008283] Status Epilepticus[MeSHID:D013226] Absence Epilepsy[MeSHID:D004832] Seizures Focal[MeSHID:D012640] Migraine Disorders[MeSHID:D008881] Disease[MeSHID:D004194] Coronavirus Infections[MeSHID:D018352] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | inhibitor |
| valproic acid | sodium channel protein | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Bipolar Disorder[MeSHID:D001714] Maintenance[MeSHID:D008283] Status Epilepticus[MeSHID:D013226] Absence Epilepsy[MeSHID:D004832] Seizures Focal[MeSHID:D012640] Migraine Disorders[MeSHID:D008881] Disease[MeSHID:D004194] Coronavirus Infections[MeSHID:D018352] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | inhibitor |
| valproic acid | sodium channel protein | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Bipolar Disorder[MeSHID:D001714] Maintenance[MeSHID:D008283] Status Epilepticus[MeSHID:D013226] Absence Epilepsy[MeSHID:D004832] Seizures Focal[MeSHID:D012640] Migraine Disorders[MeSHID:D008881] Disease[MeSHID:D004194] Coronavirus Infections[MeSHID:D018352] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | inhibitor |
| valproic acid | sodium channel protein | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Bipolar Disorder[MeSHID:D001714] Maintenance[MeSHID:D008283] Status Epilepticus[MeSHID:D013226] Absence Epilepsy[MeSHID:D004832] Seizures Focal[MeSHID:D012640] Migraine Disorders[MeSHID:D008881] Disease[MeSHID:D004194] Coronavirus Infections[MeSHID:D018352] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | inhibitor |
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