Drug-Target Information
Drug Name Target Name Drug Type Target Type Source Drug MeSHID Interaction Score Drug Status Target Action
trospium muscarinic acetylcholine receptor m1 small molecule NA drugbank , DGIDB Urge Incontinence[MeSHID:D053202]
Urination[MeSHID:D014554]
Overactive Bladder[MeSHID:D053201]
Urinary tract[MeSHID:D014551]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Neurogenesis[MeSHID:D055495]
Overactive Detrusor[MeSHID:D053201]		 1.43 approved antagonist
trospium muscarinic acetylcholine receptor m1 small molecule NA drugbank , DGIDB Urge Incontinence[MeSHID:D053202]
Urination[MeSHID:D014554]
Overactive Bladder[MeSHID:D053201]
Urinary tract[MeSHID:D014551]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Spasm[MeSHID:D013035]
Muscle Cramp[MeSHID:D009120]		 1.43 approved antagonist
trospium muscarinic acetylcholine receptor m3 small molecule NA drugbank Urge Incontinence[MeSHID:D053202]
Urination[MeSHID:D014554]
Overactive Bladder[MeSHID:D053201]
Urinary tract[MeSHID:D014551]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Spasm[MeSHID:D013035]
Muscle Cramp[MeSHID:D009120]		 NA approved unknown
trospium muscarinic acetylcholine receptor m3 small molecule NA drugbank Urge Incontinence[MeSHID:D053202]
Urination[MeSHID:D014554]
Overactive Bladder[MeSHID:D053201]
Urinary tract[MeSHID:D014551]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Neurogenesis[MeSHID:D055495]
Overactive Detrusor[MeSHID:D053201]		 NA approved unknown
trospium muscarinic acetylcholine receptor m5 NA Successful target TTD , DGIDB Urge Incontinence[MeSHID:D053202]
Urination[MeSHID:D014554]
Overactive Bladder[MeSHID:D053201]
Urinary tract[MeSHID:D014551]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Spasm[MeSHID:D013035]
Muscle Cramp[MeSHID:D009120]		 0.5 approved unknown
trospium muscarinic acetylcholine receptor m5 NA Successful target TTD , DGIDB Urge Incontinence[MeSHID:D053202]
Urination[MeSHID:D014554]
Overactive Bladder[MeSHID:D053201]
Urinary tract[MeSHID:D014551]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Neurogenesis[MeSHID:D055495]
Overactive Detrusor[MeSHID:D053201]		 0.5 approved unknown
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