| Drug-Target Information | ||||||||
|---|---|---|---|---|---|---|---|---|
| Drug Name | Target Name | Drug Type | Target Type | Source | Drug MeSHID | Interaction Score | Drug Status | Target Action |
| trimipramine | alpha-1a adrenergic receptor | small molecule | NA | drugbank | Depressive disorder[MeSHID:D003866] Dyssomnias[MeSHID:D020920] Anxiety Disorders[MeSHID:D001008] Mental Depression[MeSHID:D003863] Anxiety[MeSHID:D001007] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Major Depressive Disorder[MeSHID:D003865] Unipolar Depression[MeSHID:D003866] |
NA | approved | antagonist |
| trimipramine | alpha-1b adrenergic receptor | small molecule | NA | drugbank | Depressive disorder[MeSHID:D003866] Dyssomnias[MeSHID:D020920] Anxiety Disorders[MeSHID:D001008] Mental Depression[MeSHID:D003863] Anxiety[MeSHID:D001007] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Major Depressive Disorder[MeSHID:D003865] Unipolar Depression[MeSHID:D003866] |
NA | approved | antagonist |
| trimipramine | alpha-2a adrenergic receptor | small molecule | NA | drugbank | Depressive disorder[MeSHID:D003866] Dyssomnias[MeSHID:D020920] Anxiety Disorders[MeSHID:D001008] Mental Depression[MeSHID:D003863] Anxiety[MeSHID:D001007] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Major Depressive Disorder[MeSHID:D003865] Unipolar Depression[MeSHID:D003866] |
NA | approved | antagonist |
| trimipramine | alpha-2b adrenergic receptor | small molecule | NA | drugbank | Depressive disorder[MeSHID:D003866] Dyssomnias[MeSHID:D020920] Anxiety Disorders[MeSHID:D001008] Mental Depression[MeSHID:D003863] Anxiety[MeSHID:D001007] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Major Depressive Disorder[MeSHID:D003865] Unipolar Depression[MeSHID:D003866] |
NA | approved | unknown |
| trimipramine | beta adrenergic receptor | small molecule | NA | drugbank | Depressive disorder[MeSHID:D003866] Dyssomnias[MeSHID:D020920] Anxiety Disorders[MeSHID:D001008] Mental Depression[MeSHID:D003863] Anxiety[MeSHID:D001007] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Major Depressive Disorder[MeSHID:D003865] Unipolar Depression[MeSHID:D003866] |
NA | approved | binder |
| trimipramine | beta adrenergic receptor | small molecule | NA | drugbank | Depressive disorder[MeSHID:D003866] Dyssomnias[MeSHID:D020920] Anxiety Disorders[MeSHID:D001008] Mental Depression[MeSHID:D003863] Anxiety[MeSHID:D001007] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Major Depressive Disorder[MeSHID:D003865] Unipolar Depression[MeSHID:D003866] |
NA | approved | binder |
| trimipramine | beta adrenergic receptor | small molecule | NA | drugbank | Depressive disorder[MeSHID:D003866] Dyssomnias[MeSHID:D020920] Anxiety Disorders[MeSHID:D001008] Mental Depression[MeSHID:D003863] Anxiety[MeSHID:D001007] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Major Depressive Disorder[MeSHID:D003865] Unipolar Depression[MeSHID:D003866] |
NA | approved | binder |
| trimipramine | muscarinic acetylcholine receptor | small molecule | NA | drugbank | Depressive disorder[MeSHID:D003866] Dyssomnias[MeSHID:D020920] Anxiety Disorders[MeSHID:D001008] Mental Depression[MeSHID:D003863] Anxiety[MeSHID:D001007] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Major Depressive Disorder[MeSHID:D003865] Unipolar Depression[MeSHID:D003866] |
NA | approved | binder |
| trimipramine | muscarinic acetylcholine receptor | small molecule | NA | drugbank | Depressive disorder[MeSHID:D003866] Dyssomnias[MeSHID:D020920] Anxiety Disorders[MeSHID:D001008] Mental Depression[MeSHID:D003863] Anxiety[MeSHID:D001007] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Major Depressive Disorder[MeSHID:D003865] Unipolar Depression[MeSHID:D003866] |
NA | approved | binder |
| trimipramine | muscarinic acetylcholine receptor | small molecule | NA | drugbank | Depressive disorder[MeSHID:D003866] Dyssomnias[MeSHID:D020920] Anxiety Disorders[MeSHID:D001008] Mental Depression[MeSHID:D003863] Anxiety[MeSHID:D001007] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Major Depressive Disorder[MeSHID:D003865] Unipolar Depression[MeSHID:D003866] |
NA | approved | binder |
| trimipramine | muscarinic acetylcholine receptor | small molecule | NA | drugbank | Depressive disorder[MeSHID:D003866] Dyssomnias[MeSHID:D020920] Anxiety Disorders[MeSHID:D001008] Mental Depression[MeSHID:D003863] Anxiety[MeSHID:D001007] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Major Depressive Disorder[MeSHID:D003865] Unipolar Depression[MeSHID:D003866] |
NA | approved | binder |
| trimipramine | muscarinic acetylcholine receptor | small molecule | NA | drugbank | Depressive disorder[MeSHID:D003866] Dyssomnias[MeSHID:D020920] Anxiety Disorders[MeSHID:D001008] Mental Depression[MeSHID:D003863] Anxiety[MeSHID:D001007] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Major Depressive Disorder[MeSHID:D003865] Unipolar Depression[MeSHID:D003866] |
NA | approved | binder |
| trimipramine | d(1) dopamine receptor | small molecule | NA | drugbank , DGIDB | Depressive disorder[MeSHID:D003866] Dyssomnias[MeSHID:D020920] Anxiety Disorders[MeSHID:D001008] Mental Depression[MeSHID:D003863] Anxiety[MeSHID:D001007] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Major Depressive Disorder[MeSHID:D003865] Unipolar Depression[MeSHID:D003866] |
0.1 | approved | binder |
| trimipramine | dopamine d2 receptor | small molecule | NA | drugbank | Depressive disorder[MeSHID:D003866] Dyssomnias[MeSHID:D020920] Anxiety Disorders[MeSHID:D001008] Mental Depression[MeSHID:D003863] Anxiety[MeSHID:D001007] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Major Depressive Disorder[MeSHID:D003865] Unipolar Depression[MeSHID:D003866] |
NA | approved | unknown |
| trimipramine | d(1) dopamine receptor | small molecule | NA | drugbank | Depressive disorder[MeSHID:D003866] Dyssomnias[MeSHID:D020920] Anxiety Disorders[MeSHID:D001008] Mental Depression[MeSHID:D003863] Anxiety[MeSHID:D001007] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Major Depressive Disorder[MeSHID:D003865] Unipolar Depression[MeSHID:D003866] |
NA | approved | binder |
| trimipramine | histamine h1 receptor | small molecule | NA | drugbank | Depressive disorder[MeSHID:D003866] Dyssomnias[MeSHID:D020920] Anxiety Disorders[MeSHID:D001008] Mental Depression[MeSHID:D003863] Anxiety[MeSHID:D001007] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Major Depressive Disorder[MeSHID:D003865] Unipolar Depression[MeSHID:D003866] |
NA | approved | antagonist |
| trimipramine | 5-hydroxytryptamine receptor 1a | small molecule | NA | drugbank | Depressive disorder[MeSHID:D003866] Dyssomnias[MeSHID:D020920] Anxiety Disorders[MeSHID:D001008] Mental Depression[MeSHID:D003863] Anxiety[MeSHID:D001007] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Major Depressive Disorder[MeSHID:D003865] Unipolar Depression[MeSHID:D003866] |
NA | approved | antagonist |
| trimipramine | 5-hydroxytryptamine receptor 1d | small molecule | NA | drugbank | Depressive disorder[MeSHID:D003866] Dyssomnias[MeSHID:D020920] Anxiety Disorders[MeSHID:D001008] Mental Depression[MeSHID:D003863] Anxiety[MeSHID:D001007] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Major Depressive Disorder[MeSHID:D003865] Unipolar Depression[MeSHID:D003866] |
NA | approved | binder |
| trimipramine | 5-hydroxytryptamine receptor 2a | small molecule | NA | drugbank | Depressive disorder[MeSHID:D003866] Dyssomnias[MeSHID:D020920] Anxiety Disorders[MeSHID:D001008] Mental Depression[MeSHID:D003863] Anxiety[MeSHID:D001007] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Major Depressive Disorder[MeSHID:D003865] Unipolar Depression[MeSHID:D003866] |
NA | approved | agonist |
| trimipramine | 5-hydroxytryptamine receptor 2c | small molecule | NA | drugbank | Depressive disorder[MeSHID:D003866] Dyssomnias[MeSHID:D020920] Anxiety Disorders[MeSHID:D001008] Mental Depression[MeSHID:D003863] Anxiety[MeSHID:D001007] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Major Depressive Disorder[MeSHID:D003865] Unipolar Depression[MeSHID:D003866] |
NA | approved | antagonist |
| trimipramine | 5-hydroxytryptamine receptor 3a | small molecule | NA | drugbank | Depressive disorder[MeSHID:D003866] Dyssomnias[MeSHID:D020920] Anxiety Disorders[MeSHID:D001008] Mental Depression[MeSHID:D003863] Anxiety[MeSHID:D001007] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Major Depressive Disorder[MeSHID:D003865] Unipolar Depression[MeSHID:D003866] |
NA | approved | binder |
| trimipramine | norepinephrine transporter | NA | Successful target | TTD , DGIDB | Depressive disorder[MeSHID:D003866] Dyssomnias[MeSHID:D020920] Anxiety Disorders[MeSHID:D001008] Mental Depression[MeSHID:D003863] Anxiety[MeSHID:D001007] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Major Depressive Disorder[MeSHID:D003865] Unipolar Depression[MeSHID:D003866] |
1.14 | approved | unknown |
| trimipramine | sodium-dependent noradrenaline transporter | small molecule | NA | drugbank , DGIDB | Depressive disorder[MeSHID:D003866] Dyssomnias[MeSHID:D020920] Anxiety Disorders[MeSHID:D001008] Mental Depression[MeSHID:D003863] Anxiety[MeSHID:D001007] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Major Depressive Disorder[MeSHID:D003865] Unipolar Depression[MeSHID:D003866] |
1.14 | approved | inhibitor |
| trimipramine | norepinephrine transporter | NA | Successful target | TTD , DGIDB | Depressive disorder[MeSHID:D003866] Dyssomnias[MeSHID:D020920] Anxiety Disorders[MeSHID:D001008] Mental Depression[MeSHID:D003863] Anxiety[MeSHID:D001007] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Major Depressive Disorder[MeSHID:D003865] Unipolar Depression[MeSHID:D003866] |
1.14 | approved | inhibitor |
| trimipramine | sodium-dependent dopamine transporter | small molecule | NA | drugbank , DGIDB | Depressive disorder[MeSHID:D003866] Dyssomnias[MeSHID:D020920] Anxiety Disorders[MeSHID:D001008] Mental Depression[MeSHID:D003863] Anxiety[MeSHID:D001007] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Major Depressive Disorder[MeSHID:D003865] Unipolar Depression[MeSHID:D003866] |
0.27 | approved | inhibitor |
| trimipramine | sodium-dependent serotonin transporter | small molecule | NA | drugbank , DGIDB | Depressive disorder[MeSHID:D003866] Dyssomnias[MeSHID:D020920] Anxiety Disorders[MeSHID:D001008] Mental Depression[MeSHID:D003863] Anxiety[MeSHID:D001007] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Major Depressive Disorder[MeSHID:D003865] Unipolar Depression[MeSHID:D003866] |
0.67 | approved | inhibitor |
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