Drug-Target Information | ||||||||
---|---|---|---|---|---|---|---|---|
Drug Name | Target Name | Drug Type | Target Type | Source | Drug MeSHID | Interaction Score | Drug Status | Target Action |
trilostane | estrogen receptor alpha | small molecule | NA | drugbank | Cushing Syndrome[MeSHID:D003480] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Pituitary-dependent Cushing's disease[MeSHID:D047748] |
NA | approved,investigational,vet_approved,withdrawn | allosteric modulator |
trilostane | estrogen receptor beta | small molecule | Successful target | TTD , drugbank , DGIDB | Cushing Syndrome[MeSHID:D003480] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Pituitary-dependent Cushing's disease[MeSHID:D047748] |
0.61 | approved,investigational,vet_approved,withdrawn | allosteric modulator |
trilostane | 3 beta-hydroxysteroid dehydrogenase/delta 5-->4-isomerase type 1 | small molecule | NA | drugbank , DGIDB | Cushing Syndrome[MeSHID:D003480] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Pituitary-dependent Cushing's disease[MeSHID:D047748] |
95.48 | approved,investigational,vet_approved,withdrawn | inhibitor |
trilostane | 3 beta-hydroxysteroid dehydrogenase/delta 5-->4-isomerase type 2 | small molecule | NA | drugbank , DGIDB | Cushing Syndrome[MeSHID:D003480] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Pituitary-dependent Cushing's disease[MeSHID:D047748] |
106.09 | approved,investigational,vet_approved,withdrawn | inhibitor |
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