Drug-Target Information
Drug Name Target Name Drug Type Target Type Source Drug MeSHID Interaction Score Drug Status Target Action
trilostane estrogen receptor alpha small molecule NA drugbank Cushing Syndrome[MeSHID:D003480]
Term Birth[MeSHID:D047929]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Pituitary-dependent Cushing's disease[MeSHID:D047748]
NA approved,investigational,vet_approved,withdrawn allosteric modulator
trilostane estrogen receptor beta small molecule Successful target TTD , drugbank , DGIDB Cushing Syndrome[MeSHID:D003480]
Term Birth[MeSHID:D047929]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Pituitary-dependent Cushing's disease[MeSHID:D047748]
0.61 approved,investigational,vet_approved,withdrawn allosteric modulator
trilostane 3 beta-hydroxysteroid dehydrogenase/delta 5-->4-isomerase type 1 small molecule NA drugbank , DGIDB Cushing Syndrome[MeSHID:D003480]
Term Birth[MeSHID:D047929]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Pituitary-dependent Cushing's disease[MeSHID:D047748]
95.48 approved,investigational,vet_approved,withdrawn inhibitor
trilostane 3 beta-hydroxysteroid dehydrogenase/delta 5-->4-isomerase type 2 small molecule NA drugbank , DGIDB Cushing Syndrome[MeSHID:D003480]
Term Birth[MeSHID:D047929]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Pituitary-dependent Cushing's disease[MeSHID:D047748]
106.09 approved,investigational,vet_approved,withdrawn inhibitor
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