| Drug-Target Information | ||||||||
|---|---|---|---|---|---|---|---|---|
| Drug Name | Target Name | Drug Type | Target Type | Source | Drug MeSHID | Interaction Score | Drug Status | Target Action |
| trazodone | alpha-1a adrenergic receptor | small molecule | NA | drugbank , DGIDB | Major Depressive Disorder[MeSHID:D003865] Schizophrenia[MeSHID:D012559] Unipolar Depression[MeSHID:D003866] Disease[MeSHID:D004194] Fibromyalgia[MeSHID:D005356] Alcoholic Intoxication Chronic[MeSHID:D000437] Off-Label Use[MeSHID:D056687] Anxiety Disorders[MeSHID:D001008] Anxiety[MeSHID:D001007] Eating[MeSHID:D004435] Sleeplessness[MeSHID:D007319] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Mental Depression[MeSHID:D003863] Depressive disorder[MeSHID:D003866] |
0.13 | approved,investigational | antagonist |
| trazodone | alpha-2a adrenergic receptor | small molecule | NA | drugbank , DGIDB | Major Depressive Disorder[MeSHID:D003865] Schizophrenia[MeSHID:D012559] Unipolar Depression[MeSHID:D003866] Disease[MeSHID:D004194] Fibromyalgia[MeSHID:D005356] Alcoholic Intoxication Chronic[MeSHID:D000437] Off-Label Use[MeSHID:D056687] Anxiety Disorders[MeSHID:D001008] Anxiety[MeSHID:D001007] Eating[MeSHID:D004435] Sleeplessness[MeSHID:D007319] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Mental Depression[MeSHID:D003863] Depressive disorder[MeSHID:D003866] |
0.32 | approved,investigational | antagonist |
| trazodone | histamine h1 receptor | small molecule | NA | drugbank , DGIDB | Major Depressive Disorder[MeSHID:D003865] Schizophrenia[MeSHID:D012559] Unipolar Depression[MeSHID:D003866] Disease[MeSHID:D004194] Fibromyalgia[MeSHID:D005356] Alcoholic Intoxication Chronic[MeSHID:D000437] Off-Label Use[MeSHID:D056687] Anxiety Disorders[MeSHID:D001008] Anxiety[MeSHID:D001007] Eating[MeSHID:D004435] Sleeplessness[MeSHID:D007319] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Mental Depression[MeSHID:D003863] Depressive disorder[MeSHID:D003866] |
0.12 | approved,investigational | antagonist |
| trazodone | 5-ht 1a receptor | NA | Successful target | TTD , DGIDB | Major Depressive Disorder[MeSHID:D003865] Schizophrenia[MeSHID:D012559] Unipolar Depression[MeSHID:D003866] Disease[MeSHID:D004194] Fibromyalgia[MeSHID:D005356] Alcoholic Intoxication Chronic[MeSHID:D000437] Off-Label Use[MeSHID:D056687] Anxiety Disorders[MeSHID:D001008] Anxiety[MeSHID:D001007] Eating[MeSHID:D004435] Sleeplessness[MeSHID:D007319] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Mental Depression[MeSHID:D003863] Depressive disorder[MeSHID:D003866] |
0.3 | approved | unknown |
| trazodone | 5-hydroxytryptamine receptor 1a | small molecule | NA | drugbank , DGIDB | Major Depressive Disorder[MeSHID:D003865] Schizophrenia[MeSHID:D012559] Unipolar Depression[MeSHID:D003866] Disease[MeSHID:D004194] Fibromyalgia[MeSHID:D005356] Alcoholic Intoxication Chronic[MeSHID:D000437] Off-Label Use[MeSHID:D056687] Anxiety Disorders[MeSHID:D001008] Anxiety[MeSHID:D001007] Eating[MeSHID:D004435] Sleeplessness[MeSHID:D007319] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Mental Depression[MeSHID:D003863] Depressive disorder[MeSHID:D003866] |
0.3 | approved,investigational | antagonist,partial agonist |
| trazodone | 5-hydroxytryptamine receptor 2a | small molecule | NA | drugbank , DGIDB | Major Depressive Disorder[MeSHID:D003865] Schizophrenia[MeSHID:D012559] Unipolar Depression[MeSHID:D003866] Disease[MeSHID:D004194] Fibromyalgia[MeSHID:D005356] Alcoholic Intoxication Chronic[MeSHID:D000437] Off-Label Use[MeSHID:D056687] Anxiety Disorders[MeSHID:D001008] Anxiety[MeSHID:D001007] Eating[MeSHID:D004435] Sleeplessness[MeSHID:D007319] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Mental Depression[MeSHID:D003863] Depressive disorder[MeSHID:D003866] |
0.34 | approved,investigational | antagonist |
| trazodone | 5-hydroxytryptamine receptor 2c | small molecule | NA | drugbank , DGIDB | Major Depressive Disorder[MeSHID:D003865] Schizophrenia[MeSHID:D012559] Unipolar Depression[MeSHID:D003866] Disease[MeSHID:D004194] Fibromyalgia[MeSHID:D005356] Alcoholic Intoxication Chronic[MeSHID:D000437] Off-Label Use[MeSHID:D056687] Anxiety Disorders[MeSHID:D001008] Anxiety[MeSHID:D001007] Eating[MeSHID:D004435] Sleeplessness[MeSHID:D007319] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Mental Depression[MeSHID:D003863] Depressive disorder[MeSHID:D003866] |
0.33 | approved,investigational | agonist |
| trazodone | 5-hydroxytryptamine receptor 2c | small molecule | NA | drugbank , DGIDB | Major Depressive Disorder[MeSHID:D003865] Schizophrenia[MeSHID:D012559] Unipolar Depression[MeSHID:D003866] Disease[MeSHID:D004194] Fibromyalgia[MeSHID:D005356] Alcoholic Intoxication Chronic[MeSHID:D000437] Off-Label Use[MeSHID:D056687] Anxiety Disorders[MeSHID:D001008] Anxiety[MeSHID:D001007] Eating[MeSHID:D004435] Sleeplessness[MeSHID:D007319] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Mental Depression[MeSHID:D003863] Depressive disorder[MeSHID:D003866] |
0.33 | approved,investigational | agonist,antagonist |
| trazodone | serotonin transporter | NA | Successful target | TTD , DGIDB | Major Depressive Disorder[MeSHID:D003865] Schizophrenia[MeSHID:D012559] Unipolar Depression[MeSHID:D003866] Disease[MeSHID:D004194] Fibromyalgia[MeSHID:D005356] Alcoholic Intoxication Chronic[MeSHID:D000437] Off-Label Use[MeSHID:D056687] Anxiety Disorders[MeSHID:D001008] Anxiety[MeSHID:D001007] Eating[MeSHID:D004435] Sleeplessness[MeSHID:D007319] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Mental Depression[MeSHID:D003863] Depressive disorder[MeSHID:D003866] |
0.31 | approved | unknown |
| trazodone | sodium-dependent serotonin transporter | small molecule | NA | drugbank , DGIDB | Major Depressive Disorder[MeSHID:D003865] Schizophrenia[MeSHID:D012559] Unipolar Depression[MeSHID:D003866] Disease[MeSHID:D004194] Fibromyalgia[MeSHID:D005356] Alcoholic Intoxication Chronic[MeSHID:D000437] Off-Label Use[MeSHID:D056687] Anxiety Disorders[MeSHID:D001008] Anxiety[MeSHID:D001007] Eating[MeSHID:D004435] Sleeplessness[MeSHID:D007319] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Mental Depression[MeSHID:D003863] Depressive disorder[MeSHID:D003866] |
0.31 | approved,investigational | inhibitor |
| click here to return to the previous page | ||||||||