| Drug-Target Information | ||||||||
|---|---|---|---|---|---|---|---|---|
| Drug Name | Target Name | Drug Type | Target Type | Source | Drug MeSHID | Interaction Score | Drug Status | Target Action |
| tramadol | adenosine receptor a1 | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Pain[MeSHID:D010146] Off-Label Use[MeSHID:D056687] Premature Ejaculation[MeSHID:D061686] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | agonist |
| tramadol | alpha-2 adrenergic receptors | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Pain[MeSHID:D010146] Off-Label Use[MeSHID:D056687] Premature Ejaculation[MeSHID:D061686] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | inducer |
| tramadol | alpha-2 adrenergic receptors | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Pain[MeSHID:D010146] Off-Label Use[MeSHID:D056687] Premature Ejaculation[MeSHID:D061686] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | inducer |
| tramadol | alpha-2 adrenergic receptors | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Pain[MeSHID:D010146] Off-Label Use[MeSHID:D056687] Premature Ejaculation[MeSHID:D061686] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | inducer |
| tramadol | muscarinic acetylcholine receptor m1 | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Pain[MeSHID:D010146] Off-Label Use[MeSHID:D056687] Premature Ejaculation[MeSHID:D061686] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | antagonist |
| tramadol | muscarinic acetylcholine receptor m3 | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Pain[MeSHID:D010146] Off-Label Use[MeSHID:D056687] Premature Ejaculation[MeSHID:D061686] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | antagonist |
| tramadol | alpha-7 nicotinic cholinergic receptor subunit | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Pain[MeSHID:D010146] Off-Label Use[MeSHID:D056687] Premature Ejaculation[MeSHID:D061686] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | antagonist |
| tramadol | nmda receptor | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Pain[MeSHID:D010146] Off-Label Use[MeSHID:D056687] Premature Ejaculation[MeSHID:D061686] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | inhibitor |
| tramadol | nmda receptor | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Pain[MeSHID:D010146] Off-Label Use[MeSHID:D056687] Premature Ejaculation[MeSHID:D061686] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | inhibitor |
| tramadol | nmda receptor | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Pain[MeSHID:D010146] Off-Label Use[MeSHID:D056687] Premature Ejaculation[MeSHID:D061686] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | inhibitor |
| tramadol | nmda receptor | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Pain[MeSHID:D010146] Off-Label Use[MeSHID:D056687] Premature Ejaculation[MeSHID:D061686] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | inhibitor |
| tramadol | nmda receptor | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Pain[MeSHID:D010146] Off-Label Use[MeSHID:D056687] Premature Ejaculation[MeSHID:D061686] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | inhibitor |
| tramadol | nmda receptor | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Pain[MeSHID:D010146] Off-Label Use[MeSHID:D056687] Premature Ejaculation[MeSHID:D061686] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | inhibitor |
| tramadol | nmda receptor | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Pain[MeSHID:D010146] Off-Label Use[MeSHID:D056687] Premature Ejaculation[MeSHID:D061686] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | inhibitor |
| tramadol | 5-ht 2c receptor | NA | Successful target | TTD , DGIDB | Disease Management[MeSHID:D019468] Pain[MeSHID:D010146] Off-Label Use[MeSHID:D056687] Premature Ejaculation[MeSHID:D061686] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.18 | approved | unknown |
| tramadol | 5-hydroxytryptamine receptor 2c | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Pain[MeSHID:D010146] Off-Label Use[MeSHID:D056687] Premature Ejaculation[MeSHID:D061686] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.18 | approved,investigational | antagonist |
| tramadol | delta-type opioid receptor | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Pain[MeSHID:D010146] Off-Label Use[MeSHID:D056687] Premature Ejaculation[MeSHID:D061686] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.27 | approved,investigational | agonist |
| tramadol | kappa-type opioid receptor | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Pain[MeSHID:D010146] Off-Label Use[MeSHID:D056687] Premature Ejaculation[MeSHID:D061686] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.2 | approved,investigational | agonist |
| tramadol | mu-type opioid receptor | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Pain[MeSHID:D010146] Off-Label Use[MeSHID:D056687] Premature Ejaculation[MeSHID:D061686] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.43 | approved,investigational | agonist |
| tramadol | sodium channel protein type 2 subunit alpha | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Pain[MeSHID:D010146] Off-Label Use[MeSHID:D056687] Premature Ejaculation[MeSHID:D061686] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | inhibitor |
| tramadol | sodium-dependent noradrenaline transporter | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Pain[MeSHID:D010146] Off-Label Use[MeSHID:D056687] Premature Ejaculation[MeSHID:D061686] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.51 | approved,investigational | inhibitor |
| tramadol | sodium-dependent serotonin transporter | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Pain[MeSHID:D010146] Off-Label Use[MeSHID:D056687] Premature Ejaculation[MeSHID:D061686] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.36 | approved,investigational | inhibitor |
| tramadol | neurokinin 1 receptor | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Pain[MeSHID:D010146] Off-Label Use[MeSHID:D056687] Premature Ejaculation[MeSHID:D061686] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | inhibitor |
| tramadol | transient receptor potential cation channel subfamily v member 1 | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Pain[MeSHID:D010146] Off-Label Use[MeSHID:D056687] Premature Ejaculation[MeSHID:D061686] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | agonist |
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