| Drug-Target Information | ||||||||
|---|---|---|---|---|---|---|---|---|
| Drug Name | Target Name | Drug Type | Target Type | Source | Drug MeSHID | Interaction Score | Drug Status | Target Action |
| topotecan | dna topoisomerase 1 | small molecule | NA | drugbank , DGIDB | Disease[MeSHID:D004194] Operative Surgical Procedures[MeSHID:D013514] Malignant neoplasm of ovary[MeSHID:D010051] Neoplasm Metastasis[MeSHID:D009362] Small cell carcinoma of lung[MeSHID:D055752] Hypersensitivity[MeSHID:D006967] Recurrence (disease attribute)[MeSHID:D012008] cervical cancer[MeSHID:D002583] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Malignant Neoplasms[MeSHID:D009369] |
0.76 | approved,investigational | inhibitor |
| topotecan | dna topoisomerase i | NA | Successful target | TTD , DGIDB | Disease[MeSHID:D004194] Operative Surgical Procedures[MeSHID:D013514] Malignant neoplasm of ovary[MeSHID:D010051] Neoplasm Metastasis[MeSHID:D009362] Small cell carcinoma of lung[MeSHID:D055752] Hypersensitivity[MeSHID:D006967] Recurrence (disease attribute)[MeSHID:D012008] cervical cancer[MeSHID:D002583] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Malignant Neoplasms[MeSHID:D009369] |
0.76 | approved | unknown |
| topotecan | dna topoisomerase i, mitochondrial | small molecule | NA | drugbank , DGIDB | Disease[MeSHID:D004194] Operative Surgical Procedures[MeSHID:D013514] Malignant neoplasm of ovary[MeSHID:D010051] Neoplasm Metastasis[MeSHID:D009362] Small cell carcinoma of lung[MeSHID:D055752] Hypersensitivity[MeSHID:D006967] Recurrence (disease attribute)[MeSHID:D012008] cervical cancer[MeSHID:D002583] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Malignant Neoplasms[MeSHID:D009369] |
2.83 | approved,investigational | inhibitor |
| topotecan | dna | small molecule | NA | drugbank | Disease[MeSHID:D004194] Operative Surgical Procedures[MeSHID:D013514] Malignant neoplasm of ovary[MeSHID:D010051] Neoplasm Metastasis[MeSHID:D009362] Small cell carcinoma of lung[MeSHID:D055752] Hypersensitivity[MeSHID:D006967] Recurrence (disease attribute)[MeSHID:D012008] cervical cancer[MeSHID:D002583] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Malignant Neoplasms[MeSHID:D009369] |
NA | approved,investigational | intercalation |
| click here to return to the previous page | ||||||||