Drug-Target Information
Drug Name Target Name Drug Type Target Type Source Drug MeSHID Interaction Score Drug Status Target Action
tonapofylline adenosine a1 receptor NA Successful target TTD , DGIDB Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Congestive heart failure[MeSHID:D006333]
1.95 phase 2 unknown
tonapofylline adenosine receptor a1 small molecule NA drugbank , DGIDB Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Congestive heart failure[MeSHID:D006333]
1.95 investigational antagonist
tonapofylline adenosine receptor a1 small molecule NA drugbank , DGIDB Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Congestive heart failure[MeSHID:D006333]
1.95 investigational unknown
tonapofylline adenosine a1 receptor NA Successful target TTD , DGIDB Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Congestive heart failure[MeSHID:D006333]
1.95 phase 2 antagonist
tonapofylline adenosine a2a receptor NA Successful target TTD , DGIDB Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Congestive heart failure[MeSHID:D006333]
0.61 phase 2 antagonist
tonapofylline adenosine a2a receptor NA Successful target TTD , DGIDB Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Congestive heart failure[MeSHID:D006333]
0.61 phase 2 unknown
tonapofylline adenosine a2b receptor NA Successful target TTD , DGIDB Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Congestive heart failure[MeSHID:D006333]
0.86 phase 2 unknown
tonapofylline adenosine a2b receptor NA Successful target TTD , DGIDB Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Congestive heart failure[MeSHID:D006333]
0.86 phase 2 antagonist
tonapofylline adenosine a3 receptor NA Clinical trial target TTD , DGIDB Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Congestive heart failure[MeSHID:D006333]
0.8 phase 2 antagonist
tonapofylline adenosine a3 receptor NA Clinical trial target TTD , DGIDB Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Congestive heart failure[MeSHID:D006333]
0.8 phase 2 unknown
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