Drug-Target Information
Drug Name Target Name Drug Type Target Type Source Drug MeSHID Interaction Score Drug Status Target Action
tizanidine alpha-1 adrenergic receptors small molecule NA drugbank Muscle Spasticity[MeSHID:D009128]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Spasm[MeSHID:D013035]
Muscle Cramp[MeSHID:D009120]		 NA approved,investigational agonist
tizanidine alpha-1 adrenergic receptors small molecule NA drugbank Muscle Spasticity[MeSHID:D009128]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Spasm[MeSHID:D013035]
Muscle Cramp[MeSHID:D009120]		 NA approved,investigational agonist
tizanidine alpha-1 adrenergic receptors small molecule NA drugbank Muscle Spasticity[MeSHID:D009128]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Spasm[MeSHID:D013035]
Muscle Cramp[MeSHID:D009120]		 NA approved,investigational agonist
tizanidine alpha-2 adrenergic receptors small molecule NA drugbank , DGIDB Muscle Spasticity[MeSHID:D009128]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Spasm[MeSHID:D013035]
Muscle Cramp[MeSHID:D009120]		 1.3 approved,investigational agonist
tizanidine alpha-2 adrenergic receptors small molecule NA drugbank , DGIDB Muscle Spasticity[MeSHID:D009128]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Spasm[MeSHID:D013035]
Muscle Cramp[MeSHID:D009120]		 0.45 approved,investigational agonist
tizanidine alpha-2 adrenergic receptors small molecule NA drugbank , DGIDB Muscle Spasticity[MeSHID:D009128]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Spasm[MeSHID:D013035]
Muscle Cramp[MeSHID:D009120]		 0.38 approved,investigational agonist
tizanidine nischarin small molecule NA drugbank Muscle Spasticity[MeSHID:D009128]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Spasm[MeSHID:D013035]
Muscle Cramp[MeSHID:D009120]		 NA approved,investigational agonist
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