| Drug-Target Information | ||||||||
|---|---|---|---|---|---|---|---|---|
| Drug Name | Target Name | Drug Type | Target Type | Source | Drug MeSHID | Interaction Score | Drug Status | Target Action |
| theophylline | adenosine receptor a1 | small molecule | NA | drugbank , DGIDB | Lung diseases[MeSHID:D008171] Pathological accumulation of air in tissues[MeSHID:D004646] Asthma[MeSHID:D001249] Lung[MeSHID:D008168] Pulmonary Emphysema[MeSHID:D011656] Bronchitis Chronic[MeSHID:D029481] Chronic disease[MeSHID:D002908] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Chronic Obstructive Airway Disease[MeSHID:D029424] |
0.32 | approved | antagonist |
| theophylline | adenosine receptor a2a | small molecule | NA | drugbank , DGIDB | Lung diseases[MeSHID:D008171] Pathological accumulation of air in tissues[MeSHID:D004646] Asthma[MeSHID:D001249] Lung[MeSHID:D008168] Pulmonary Emphysema[MeSHID:D011656] Bronchitis Chronic[MeSHID:D029481] Chronic disease[MeSHID:D002908] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Chronic Obstructive Airway Disease[MeSHID:D029424] |
0.26 | approved | antagonist |
| theophylline | adenosine receptor a2b | small molecule | NA | drugbank , DGIDB | Lung diseases[MeSHID:D008171] Pathological accumulation of air in tissues[MeSHID:D004646] Asthma[MeSHID:D001249] Lung[MeSHID:D008168] Pulmonary Emphysema[MeSHID:D011656] Bronchitis Chronic[MeSHID:D029481] Chronic disease[MeSHID:D002908] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Chronic Obstructive Airway Disease[MeSHID:D029424] |
0.72 | approved | antagonist |
| theophylline | copine-1 | small molecule | NA | drugbank | Lung diseases[MeSHID:D008171] Pathological accumulation of air in tissues[MeSHID:D004646] Asthma[MeSHID:D001249] Lung[MeSHID:D008168] Pulmonary Emphysema[MeSHID:D011656] Bronchitis Chronic[MeSHID:D029481] Chronic disease[MeSHID:D002908] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Chronic Obstructive Airway Disease[MeSHID:D029424] |
NA | approved | unknown |
| theophylline | histone deacetylase 2 | small molecule | NA | drugbank | Lung diseases[MeSHID:D008171] Pathological accumulation of air in tissues[MeSHID:D004646] Asthma[MeSHID:D001249] Lung[MeSHID:D008168] Pulmonary Emphysema[MeSHID:D011656] Bronchitis Chronic[MeSHID:D029481] Chronic disease[MeSHID:D002908] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Chronic Obstructive Airway Disease[MeSHID:D029424] |
NA | approved | activator |
| theophylline | minor histocompatibility antigen h13 | small molecule | NA | drugbank | Lung diseases[MeSHID:D008171] Pathological accumulation of air in tissues[MeSHID:D004646] Asthma[MeSHID:D001249] Lung[MeSHID:D008168] Pulmonary Emphysema[MeSHID:D011656] Bronchitis Chronic[MeSHID:D029481] Chronic disease[MeSHID:D002908] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Chronic Obstructive Airway Disease[MeSHID:D029424] |
NA | approved | unknown |
| theophylline | nodal modulator 1 | small molecule | NA | drugbank | Lung diseases[MeSHID:D008171] Pathological accumulation of air in tissues[MeSHID:D004646] Asthma[MeSHID:D001249] Lung[MeSHID:D008168] Pulmonary Emphysema[MeSHID:D011656] Bronchitis Chronic[MeSHID:D029481] Chronic disease[MeSHID:D002908] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Chronic Obstructive Airway Disease[MeSHID:D029424] |
NA | approved | unknown |
| theophylline | poly [adp-ribose] polymerase 1 | small molecule | NA | drugbank | Lung diseases[MeSHID:D008171] Pathological accumulation of air in tissues[MeSHID:D004646] Asthma[MeSHID:D001249] Lung[MeSHID:D008168] Pulmonary Emphysema[MeSHID:D011656] Bronchitis Chronic[MeSHID:D029481] Chronic disease[MeSHID:D002908] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Chronic Obstructive Airway Disease[MeSHID:D029424] |
NA | approved | unknown |
| theophylline | cgmp-inhibited 3',5'-cyclic phosphodiesterase a | small molecule | NA | drugbank , DGIDB | Lung diseases[MeSHID:D008171] Pathological accumulation of air in tissues[MeSHID:D004646] Asthma[MeSHID:D001249] Lung[MeSHID:D008168] Pulmonary Emphysema[MeSHID:D011656] Bronchitis Chronic[MeSHID:D029481] Chronic disease[MeSHID:D002908] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Chronic Obstructive Airway Disease[MeSHID:D029424] |
0.69 | approved | inhibitor |
| theophylline | camp-specific 3',5'-cyclic phosphodiesterase 4a | small molecule | NA | drugbank , DGIDB | Lung diseases[MeSHID:D008171] Pathological accumulation of air in tissues[MeSHID:D004646] Asthma[MeSHID:D001249] Lung[MeSHID:D008168] Pulmonary Emphysema[MeSHID:D011656] Bronchitis Chronic[MeSHID:D029481] Chronic disease[MeSHID:D002908] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Chronic Obstructive Airway Disease[MeSHID:D029424] |
0.68 | approved | inhibitor |
| theophylline | camp-specific 3',5'-cyclic phosphodiesterase 4b | small molecule | NA | drugbank , DGIDB | Lung diseases[MeSHID:D008171] Pathological accumulation of air in tissues[MeSHID:D004646] Asthma[MeSHID:D001249] Lung[MeSHID:D008168] Pulmonary Emphysema[MeSHID:D011656] Bronchitis Chronic[MeSHID:D029481] Chronic disease[MeSHID:D002908] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Chronic Obstructive Airway Disease[MeSHID:D029424] |
0.32 | approved | inhibitor |
| theophylline | cgmp-specific 3',5'-cyclic phosphodiesterase | small molecule | NA | drugbank , DGIDB | Lung diseases[MeSHID:D008171] Pathological accumulation of air in tissues[MeSHID:D004646] Asthma[MeSHID:D001249] Lung[MeSHID:D008168] Pulmonary Emphysema[MeSHID:D011656] Bronchitis Chronic[MeSHID:D029481] Chronic disease[MeSHID:D002908] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Chronic Obstructive Airway Disease[MeSHID:D029424] |
0.33 | approved | inhibitor |
| theophylline | protein ric-3 | small molecule | NA | drugbank | Lung diseases[MeSHID:D008171] Pathological accumulation of air in tissues[MeSHID:D004646] Asthma[MeSHID:D001249] Lung[MeSHID:D008168] Pulmonary Emphysema[MeSHID:D011656] Bronchitis Chronic[MeSHID:D029481] Chronic disease[MeSHID:D002908] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Chronic Obstructive Airway Disease[MeSHID:D029424] |
NA | approved | unknown |
| theophylline | tubulin monoglycylase ttll3 | small molecule | NA | drugbank | Lung diseases[MeSHID:D008171] Pathological accumulation of air in tissues[MeSHID:D004646] Asthma[MeSHID:D001249] Lung[MeSHID:D008168] Pulmonary Emphysema[MeSHID:D011656] Bronchitis Chronic[MeSHID:D029481] Chronic disease[MeSHID:D002908] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Chronic Obstructive Airway Disease[MeSHID:D029424] |
NA | approved | unknown |
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