Drug-Target Information
Drug Name Target Name Drug Type Target Type Source Drug MeSHID Interaction Score Drug Status Target Action
terfenadine muscarinic acetylcholine receptor m1 small molecule NA drugbank Dermatologic disorders[MeSHID:D012871]
Hay fever[MeSHID:D006255]
Hypersensitivity[MeSHID:D006967]
Allergic rhinitis (disorder)[MeSHID:D065631]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Allergic Reaction[MeSHID:D006967]		 NA approved,withdrawn binder
terfenadine muscarinic acetylcholine receptor m2 small molecule NA drugbank Dermatologic disorders[MeSHID:D012871]
Hay fever[MeSHID:D006255]
Hypersensitivity[MeSHID:D006967]
Allergic rhinitis (disorder)[MeSHID:D065631]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Allergic Reaction[MeSHID:D006967]		 NA approved,withdrawn binder
terfenadine muscarinic acetylcholine receptor m3 small molecule NA drugbank Dermatologic disorders[MeSHID:D012871]
Hay fever[MeSHID:D006255]
Hypersensitivity[MeSHID:D006967]
Allergic rhinitis (disorder)[MeSHID:D065631]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Allergic Reaction[MeSHID:D006967]		 NA approved,withdrawn antagonist
terfenadine muscarinic acetylcholine receptor m4 small molecule NA drugbank Dermatologic disorders[MeSHID:D012871]
Hay fever[MeSHID:D006255]
Hypersensitivity[MeSHID:D006967]
Allergic rhinitis (disorder)[MeSHID:D065631]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Allergic Reaction[MeSHID:D006967]		 NA approved,withdrawn binder
terfenadine muscarinic acetylcholine receptor m5 small molecule NA drugbank Dermatologic disorders[MeSHID:D012871]
Hay fever[MeSHID:D006255]
Hypersensitivity[MeSHID:D006967]
Allergic rhinitis (disorder)[MeSHID:D065631]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Allergic Reaction[MeSHID:D006967]		 NA approved,withdrawn binder
terfenadine histamine h1 receptor small molecule Successful target TTD , drugbank , DGIDB Dermatologic disorders[MeSHID:D012871]
Hay fever[MeSHID:D006255]
Hypersensitivity[MeSHID:D006967]
Allergic rhinitis (disorder)[MeSHID:D065631]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Allergic Reaction[MeSHID:D006967]		 0.24 approved,withdrawn,withdrawn from market antagonist
terfenadine potassium voltage-gated channel subfamily h member 2 small molecule NA drugbank , DGIDB Dermatologic disorders[MeSHID:D012871]
Hay fever[MeSHID:D006255]
Hypersensitivity[MeSHID:D006967]
Allergic rhinitis (disorder)[MeSHID:D065631]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Allergic Reaction[MeSHID:D006967]		 0.12 approved,withdrawn inhibitor
terfenadine potassium voltage-gated channel subfamily h member 2 small molecule NA drugbank , DGIDB Dermatologic disorders[MeSHID:D012871]
Hay fever[MeSHID:D006255]
Hypersensitivity[MeSHID:D006967]
Allergic rhinitis (disorder)[MeSHID:D065631]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Allergic Reaction[MeSHID:D006967]		 0.12 approved,withdrawn inhibitor,blocker
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