| Drug-Target Information | ||||||||
|---|---|---|---|---|---|---|---|---|
| Drug Name | Target Name | Drug Type | Target Type | Source | Drug MeSHID | Interaction Score | Drug Status | Target Action |
| tamoxifen | androgen receptor | small molecule | NA | drugbank | Breast[MeSHID:D001940] Radiation[MeSHID:D011827] Noninfiltrating Intraductal Carcinoma[MeSHID:D002285] Operative Surgical Procedures[MeSHID:D013514] Neoplasm Metastasis[MeSHID:D009362] Malignant neoplasm of breast[MeSHID:D001943] Electromagnetic Radiation[MeSHID:D060733] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | unknown |
| tamoxifen | 3-beta-hydroxysteroid-delta(8),delta(7)-isomerase | small molecule | NA | drugbank | Breast[MeSHID:D001940] Radiation[MeSHID:D011827] Noninfiltrating Intraductal Carcinoma[MeSHID:D002285] Operative Surgical Procedures[MeSHID:D013514] Neoplasm Metastasis[MeSHID:D009362] Malignant neoplasm of breast[MeSHID:D001943] Electromagnetic Radiation[MeSHID:D060733] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | inhibitor |
| tamoxifen | estrogen receptor alpha | small molecule | NA | drugbank , DGIDB | Breast[MeSHID:D001940] Radiation[MeSHID:D011827] Noninfiltrating Intraductal Carcinoma[MeSHID:D002285] Operative Surgical Procedures[MeSHID:D013514] Neoplasm Metastasis[MeSHID:D009362] Malignant neoplasm of breast[MeSHID:D001943] Electromagnetic Radiation[MeSHID:D060733] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.11 | approved | antagonist,agonist |
| tamoxifen | estrogen receptor | NA | Successful target | TTD , DGIDB | Breast[MeSHID:D001940] Radiation[MeSHID:D011827] Noninfiltrating Intraductal Carcinoma[MeSHID:D002285] Operative Surgical Procedures[MeSHID:D013514] Neoplasm Metastasis[MeSHID:D009362] Malignant neoplasm of breast[MeSHID:D001943] Electromagnetic Radiation[MeSHID:D060733] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.11 | approved | agonist,antagonist |
| tamoxifen | estrogen receptor | NA | Successful target | TTD , DGIDB | Breast[MeSHID:D001940] Radiation[MeSHID:D011827] Noninfiltrating Intraductal Carcinoma[MeSHID:D002285] Operative Surgical Procedures[MeSHID:D013514] Neoplasm Metastasis[MeSHID:D009362] Malignant neoplasm of breast[MeSHID:D001943] Electromagnetic Radiation[MeSHID:D060733] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.11 | approved | unknown |
| tamoxifen | estrogen receptor beta | small molecule | NA | drugbank , DGIDB | Breast[MeSHID:D001940] Radiation[MeSHID:D011827] Noninfiltrating Intraductal Carcinoma[MeSHID:D002285] Operative Surgical Procedures[MeSHID:D013514] Neoplasm Metastasis[MeSHID:D009362] Malignant neoplasm of breast[MeSHID:D001943] Electromagnetic Radiation[MeSHID:D060733] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.23 | approved | antagonist,agonist |
| tamoxifen | estrogen-related receptor gamma | small molecule | NA | drugbank | Breast[MeSHID:D001940] Radiation[MeSHID:D011827] Noninfiltrating Intraductal Carcinoma[MeSHID:D002285] Operative Surgical Procedures[MeSHID:D013514] Neoplasm Metastasis[MeSHID:D009362] Malignant neoplasm of breast[MeSHID:D001943] Electromagnetic Radiation[MeSHID:D060733] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | unknown |
| tamoxifen | potassium voltage-gated channel subfamily h member 2 | small molecule | NA | drugbank | Breast[MeSHID:D001940] Radiation[MeSHID:D011827] Noninfiltrating Intraductal Carcinoma[MeSHID:D002285] Operative Surgical Procedures[MeSHID:D013514] Neoplasm Metastasis[MeSHID:D009362] Malignant neoplasm of breast[MeSHID:D001943] Electromagnetic Radiation[MeSHID:D060733] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | inhibitor |
| tamoxifen | mitogen-activated protein kinase 8 | small molecule | NA | drugbank | Breast[MeSHID:D001940] Radiation[MeSHID:D011827] Noninfiltrating Intraductal Carcinoma[MeSHID:D002285] Operative Surgical Procedures[MeSHID:D013514] Neoplasm Metastasis[MeSHID:D009362] Malignant neoplasm of breast[MeSHID:D001943] Electromagnetic Radiation[MeSHID:D060733] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | modulator |
| tamoxifen | nuclear receptor subfamily 1 group i member 2 | small molecule | NA | drugbank , DGIDB | Breast[MeSHID:D001940] Radiation[MeSHID:D011827] Noninfiltrating Intraductal Carcinoma[MeSHID:D002285] Operative Surgical Procedures[MeSHID:D013514] Neoplasm Metastasis[MeSHID:D009362] Malignant neoplasm of breast[MeSHID:D001943] Electromagnetic Radiation[MeSHID:D060733] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.03 | approved | unknown |
| tamoxifen | protein kinase c | small molecule | NA | drugbank | Breast[MeSHID:D001940] Radiation[MeSHID:D011827] Noninfiltrating Intraductal Carcinoma[MeSHID:D002285] Operative Surgical Procedures[MeSHID:D013514] Neoplasm Metastasis[MeSHID:D009362] Malignant neoplasm of breast[MeSHID:D001943] Electromagnetic Radiation[MeSHID:D060733] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | inhibitor |
| tamoxifen | protein kinase c | small molecule | NA | drugbank | Breast[MeSHID:D001940] Radiation[MeSHID:D011827] Noninfiltrating Intraductal Carcinoma[MeSHID:D002285] Operative Surgical Procedures[MeSHID:D013514] Neoplasm Metastasis[MeSHID:D009362] Malignant neoplasm of breast[MeSHID:D001943] Electromagnetic Radiation[MeSHID:D060733] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | inhibitor |
| tamoxifen | protein kinase c | small molecule | NA | drugbank | Breast[MeSHID:D001940] Radiation[MeSHID:D011827] Noninfiltrating Intraductal Carcinoma[MeSHID:D002285] Operative Surgical Procedures[MeSHID:D013514] Neoplasm Metastasis[MeSHID:D009362] Malignant neoplasm of breast[MeSHID:D001943] Electromagnetic Radiation[MeSHID:D060733] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | inhibitor |
| tamoxifen | protein kinase c | small molecule | NA | drugbank | Breast[MeSHID:D001940] Radiation[MeSHID:D011827] Noninfiltrating Intraductal Carcinoma[MeSHID:D002285] Operative Surgical Procedures[MeSHID:D013514] Neoplasm Metastasis[MeSHID:D009362] Malignant neoplasm of breast[MeSHID:D001943] Electromagnetic Radiation[MeSHID:D060733] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | inhibitor |
| tamoxifen | protein kinase c | small molecule | NA | drugbank | Breast[MeSHID:D001940] Radiation[MeSHID:D011827] Noninfiltrating Intraductal Carcinoma[MeSHID:D002285] Operative Surgical Procedures[MeSHID:D013514] Neoplasm Metastasis[MeSHID:D009362] Malignant neoplasm of breast[MeSHID:D001943] Electromagnetic Radiation[MeSHID:D060733] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | inhibitor |
| tamoxifen | protein kinase c | small molecule | NA | drugbank | Breast[MeSHID:D001940] Radiation[MeSHID:D011827] Noninfiltrating Intraductal Carcinoma[MeSHID:D002285] Operative Surgical Procedures[MeSHID:D013514] Neoplasm Metastasis[MeSHID:D009362] Malignant neoplasm of breast[MeSHID:D001943] Electromagnetic Radiation[MeSHID:D060733] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | inhibitor |
| tamoxifen | protein kinase c | small molecule | NA | drugbank | Breast[MeSHID:D001940] Radiation[MeSHID:D011827] Noninfiltrating Intraductal Carcinoma[MeSHID:D002285] Operative Surgical Procedures[MeSHID:D013514] Neoplasm Metastasis[MeSHID:D009362] Malignant neoplasm of breast[MeSHID:D001943] Electromagnetic Radiation[MeSHID:D060733] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | inhibitor |
| tamoxifen | protein kinase c | small molecule | NA | drugbank | Breast[MeSHID:D001940] Radiation[MeSHID:D011827] Noninfiltrating Intraductal Carcinoma[MeSHID:D002285] Operative Surgical Procedures[MeSHID:D013514] Neoplasm Metastasis[MeSHID:D009362] Malignant neoplasm of breast[MeSHID:D001943] Electromagnetic Radiation[MeSHID:D060733] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | inhibitor |
| tamoxifen | sex hormone-binding globulin | small molecule | NA | drugbank | Breast[MeSHID:D001940] Radiation[MeSHID:D011827] Noninfiltrating Intraductal Carcinoma[MeSHID:D002285] Operative Surgical Procedures[MeSHID:D013514] Neoplasm Metastasis[MeSHID:D009362] Malignant neoplasm of breast[MeSHID:D001943] Electromagnetic Radiation[MeSHID:D060733] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | inducer |
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