| Drug-Target Information | ||||||||
|---|---|---|---|---|---|---|---|---|
| Drug Name | Target Name | Drug Type | Target Type | Source | Drug MeSHID | Interaction Score | Drug Status | Target Action |
| tadalafil | dual 3',5'-cyclic-amp and -gmp phosphodiesterase 11a | small molecule | NA | drugbank , DGIDB | Benign prostatic hypertrophy[MeSHID:D011470] Idiopathic pulmonary arterial hypertension[MeSHID:D065627] Erectile dysfunction[MeSHID:D007172] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
47.74 | approved,investigational | inhibitor |
| tadalafil | phosphodiesterase 5a | NA | Successful target | TTD , DGIDB | Benign prostatic hypertrophy[MeSHID:D011470] Idiopathic pulmonary arterial hypertension[MeSHID:D065627] Erectile dysfunction[MeSHID:D007172] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
7.96 | approved | inhibitor |
| tadalafil | cgmp-specific 3',5'-cyclic phosphodiesterase | small molecule | NA | drugbank , DGIDB | Benign prostatic hypertrophy[MeSHID:D011470] Idiopathic pulmonary arterial hypertension[MeSHID:D065627] Erectile dysfunction[MeSHID:D007172] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
7.96 | approved,investigational | inhibitor |
| tadalafil | phosphodiesterase 5a | NA | Successful target | TTD , DGIDB | Benign prostatic hypertrophy[MeSHID:D011470] Idiopathic pulmonary arterial hypertension[MeSHID:D065627] Erectile dysfunction[MeSHID:D007172] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
7.96 | approved | unknown |
| tadalafil | retinal rod rhodopsin-sensitive cgmp 3',5'-cyclic phosphodiesterase subunit gamma | small molecule | NA | drugbank | Benign prostatic hypertrophy[MeSHID:D011470] Idiopathic pulmonary arterial hypertension[MeSHID:D065627] Erectile dysfunction[MeSHID:D007172] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | inhibitor |
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