| Drug-Target Information | ||||||||
|---|---|---|---|---|---|---|---|---|
| Drug Name | Target Name | Drug Type | Target Type | Source | Drug MeSHID | Interaction Score | Drug Status | Target Action |
| suramin | prothrombin | small molecule | NA | drugbank | Disease[MeSHID:D004194] African Trypanosomiasis[MeSHID:D014353] Onchocerciasis[MeSHID:D009855] Helminthiasis[MeSHID:D006373] Trematode Infections[MeSHID:D014201] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | investigational | inhibitor |
| suramin | prothrombin | small molecule | NA | drugbank | Disease[MeSHID:D004194] African Trypanosomiasis[MeSHID:D014353] Onchocerciasis[MeSHID:D009855] Helminthiasis[MeSHID:D006373] Trematode Infections[MeSHID:D014201] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Coronavirus Infections[MeSHID:D018352] |
NA | investigational | inhibitor |
| suramin | follicle-stimulating hormone receptor | small molecule | Successful target | TTD , drugbank , DGIDB | Disease[MeSHID:D004194] African Trypanosomiasis[MeSHID:D014353] Onchocerciasis[MeSHID:D009855] Helminthiasis[MeSHID:D006373] Trematode Infections[MeSHID:D014201] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Coronavirus Infections[MeSHID:D018352] |
1.26 | investigational,phase 1 | antagonist |
| suramin | follicle-stimulating hormone receptor | small molecule | Successful target | TTD , drugbank , DGIDB | Disease[MeSHID:D004194] African Trypanosomiasis[MeSHID:D014353] Onchocerciasis[MeSHID:D009855] Helminthiasis[MeSHID:D006373] Trematode Infections[MeSHID:D014201] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
1.26 | investigational,phase 1 | antagonist |
| suramin | heparanase | NA | Successful target | TTD , DGIDB | Disease[MeSHID:D004194] African Trypanosomiasis[MeSHID:D014353] Onchocerciasis[MeSHID:D009855] Helminthiasis[MeSHID:D006373] Trematode Infections[MeSHID:D014201] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.13 | phase 1 | unknown |
| suramin | heparanase | NA | Successful target | TTD , DGIDB | Disease[MeSHID:D004194] African Trypanosomiasis[MeSHID:D014353] Onchocerciasis[MeSHID:D009855] Helminthiasis[MeSHID:D006373] Trematode Infections[MeSHID:D014201] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Coronavirus Infections[MeSHID:D018352] |
0.13 | phase 1 | unknown |
| suramin | p2y purinoceptor 2 | small molecule | NA | drugbank , DGIDB | Disease[MeSHID:D004194] African Trypanosomiasis[MeSHID:D014353] Onchocerciasis[MeSHID:D009855] Helminthiasis[MeSHID:D006373] Trematode Infections[MeSHID:D014201] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Coronavirus Infections[MeSHID:D018352] |
1.12 | investigational | antagonist |
| suramin | p2y purinoceptor 2 | small molecule | NA | drugbank , DGIDB | Disease[MeSHID:D004194] African Trypanosomiasis[MeSHID:D014353] Onchocerciasis[MeSHID:D009855] Helminthiasis[MeSHID:D006373] Trematode Infections[MeSHID:D014201] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
1.12 | investigational | antagonist |
| suramin | phospholipase a2, membrane associated | small molecule | NA | drugbank | Disease[MeSHID:D004194] African Trypanosomiasis[MeSHID:D014353] Onchocerciasis[MeSHID:D009855] Helminthiasis[MeSHID:D006373] Trematode Infections[MeSHID:D014201] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Coronavirus Infections[MeSHID:D018352] |
NA | investigational | inhibitor |
| suramin | phospholipase a2, membrane associated | small molecule | NA | drugbank | Disease[MeSHID:D004194] African Trypanosomiasis[MeSHID:D014353] Onchocerciasis[MeSHID:D009855] Helminthiasis[MeSHID:D006373] Trematode Infections[MeSHID:D014201] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | investigational | inhibitor |
| suramin | ryanodine receptor 1 | small molecule | NA | drugbank , DGIDB | Disease[MeSHID:D004194] African Trypanosomiasis[MeSHID:D014353] Onchocerciasis[MeSHID:D009855] Helminthiasis[MeSHID:D006373] Trematode Infections[MeSHID:D014201] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.21 | investigational | agonist,activator |
| suramin | ryanodine receptor 1 | small molecule | NA | drugbank , DGIDB | Disease[MeSHID:D004194] African Trypanosomiasis[MeSHID:D014353] Onchocerciasis[MeSHID:D009855] Helminthiasis[MeSHID:D006373] Trematode Infections[MeSHID:D014201] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Coronavirus Infections[MeSHID:D018352] |
0.21 | investigational | agonist,activator |
| suramin | nad-dependent protein deacylase sirtuin-5, mitochondrial | small molecule | NA | drugbank , DGIDB | Disease[MeSHID:D004194] African Trypanosomiasis[MeSHID:D014353] Onchocerciasis[MeSHID:D009855] Helminthiasis[MeSHID:D006373] Trematode Infections[MeSHID:D014201] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
1.12 | investigational | inhibitor |
| suramin | nad-dependent protein deacylase sirtuin-5, mitochondrial | small molecule | NA | drugbank , DGIDB | Disease[MeSHID:D004194] African Trypanosomiasis[MeSHID:D014353] Onchocerciasis[MeSHID:D009855] Helminthiasis[MeSHID:D006373] Trematode Infections[MeSHID:D014201] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Coronavirus Infections[MeSHID:D018352] |
1.12 | investigational | inhibitor |
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