| Drug-Target Information | ||||||||
|---|---|---|---|---|---|---|---|---|
| Drug Name | Target Name | Drug Type | Target Type | Source | Drug MeSHID | Interaction Score | Drug Status | Target Action |
| sulindac | aldose reductase | small molecule | Successful target | TTD , drugbank , DGIDB | Degenerative polyarthritis[MeSHID:D010003] Acute onset pain[MeSHID:D059787] Tendinitis[MeSHID:D052256] Ankylosing spondylitis[MeSHID:D013167] Rheumatoid Arthritis[MeSHID:D001172] Arthritis Gouty[MeSHID:D015210] Bursitis[MeSHID:D002062] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
1.9 | approved,investigational | inhibitor |
| sulindac | aldo-keto reductase family 1 member b10 | small molecule | NA | drugbank | Degenerative polyarthritis[MeSHID:D010003] Acute onset pain[MeSHID:D059787] Tendinitis[MeSHID:D052256] Ankylosing spondylitis[MeSHID:D013167] Rheumatoid Arthritis[MeSHID:D001172] Arthritis Gouty[MeSHID:D015210] Bursitis[MeSHID:D002062] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | inhibitor |
| sulindac | mitogen-activated protein kinase 3 | small molecule | NA | drugbank | Degenerative polyarthritis[MeSHID:D010003] Acute onset pain[MeSHID:D059787] Tendinitis[MeSHID:D052256] Ankylosing spondylitis[MeSHID:D013167] Rheumatoid Arthritis[MeSHID:D001172] Arthritis Gouty[MeSHID:D015210] Bursitis[MeSHID:D002062] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | inhibitor |
| sulindac | peroxisome proliferator-activated receptor delta | small molecule | NA | drugbank | Degenerative polyarthritis[MeSHID:D010003] Acute onset pain[MeSHID:D059787] Tendinitis[MeSHID:D052256] Ankylosing spondylitis[MeSHID:D013167] Rheumatoid Arthritis[MeSHID:D001172] Arthritis Gouty[MeSHID:D015210] Bursitis[MeSHID:D002062] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | negative modulator |
| sulindac | prostaglandin d2 receptor 2 | small molecule | NA | drugbank | Degenerative polyarthritis[MeSHID:D010003] Acute onset pain[MeSHID:D059787] Tendinitis[MeSHID:D052256] Ankylosing spondylitis[MeSHID:D013167] Rheumatoid Arthritis[MeSHID:D001172] Arthritis Gouty[MeSHID:D015210] Bursitis[MeSHID:D002062] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | antagonist |
| sulindac | prostaglandin g/h synthase 1 | small molecule | NA | drugbank , DGIDB | Degenerative polyarthritis[MeSHID:D010003] Acute onset pain[MeSHID:D059787] Tendinitis[MeSHID:D052256] Ankylosing spondylitis[MeSHID:D013167] Rheumatoid Arthritis[MeSHID:D001172] Arthritis Gouty[MeSHID:D015210] Bursitis[MeSHID:D002062] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.48 | approved,investigational | inhibitor |
| sulindac | prostaglandin g/h synthase 2 | small molecule | NA | drugbank , DGIDB | Degenerative polyarthritis[MeSHID:D010003] Acute onset pain[MeSHID:D059787] Tendinitis[MeSHID:D052256] Ankylosing spondylitis[MeSHID:D013167] Rheumatoid Arthritis[MeSHID:D001172] Arthritis Gouty[MeSHID:D015210] Bursitis[MeSHID:D002062] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.36 | approved,investigational | inhibitor |
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