Drug-Target Information | ||||||||
---|---|---|---|---|---|---|---|---|
Drug Name | Target Name | Drug Type | Target Type | Source | Drug MeSHID | Interaction Score | Drug Status | Target Action |
spironolactone | androgen receptor | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Operative Surgical Procedures[MeSHID:D013514] Heart failure[MeSHID:D006333] Heart[MeSHID:D006321] Acne Vulgaris[MeSHID:D000152] Nephrotic Syndrome[MeSHID:D009404] Mental association[MeSHID:D001244] Off-Label Use[MeSHID:D056687] Term Birth[MeSHID:D047929] Hypertensive disease[MeSHID:D006973] Congenital adrenal hyperplasia[MeSHID:D000312] Disease[MeSHID:D004194] Edema[MeSHID:D004487] treatment failure[MeSHID:D017211] Adrenal Cortical Adenoma[MeSHID:D018246] Hirsutism[MeSHID:D006628] Androgenetic Alopecia[MeSHID:D000505] Hair[MeSHID:D006197] Body Fluids[MeSHID:D001826] Acne Adult[MeSHID:C565791] Growth[MeSHID:D006128] Conn Syndrome[MeSHID:D006929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Congestive heart failure[MeSHID:D006333] |
0.01 | approved | antagonist |
spironolactone | androgen receptor | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Operative Surgical Procedures[MeSHID:D013514] Heart failure[MeSHID:D006333] Heart[MeSHID:D006321] Acne Vulgaris[MeSHID:D000152] Nephrotic Syndrome[MeSHID:D009404] Mental association[MeSHID:D001244] Off-Label Use[MeSHID:D056687] Term Birth[MeSHID:D047929] Hypertensive disease[MeSHID:D006973] Congenital adrenal hyperplasia[MeSHID:D000312] Disease[MeSHID:D004194] Edema[MeSHID:D004487] treatment failure[MeSHID:D017211] Adrenal Cortical Adenoma[MeSHID:D018246] Hirsutism[MeSHID:D006628] Androgenetic Alopecia[MeSHID:D000505] Hair[MeSHID:D006197] Body Fluids[MeSHID:D001826] Acne Adult[MeSHID:C565791] Growth[MeSHID:D006128] Conn Syndrome[MeSHID:D006929] Coronavirus Infections[MeSHID:D018352] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.01 | approved | antagonist |
spironolactone | voltage-dependent calcium channel | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Operative Surgical Procedures[MeSHID:D013514] Heart failure[MeSHID:D006333] Heart[MeSHID:D006321] Acne Vulgaris[MeSHID:D000152] Nephrotic Syndrome[MeSHID:D009404] Mental association[MeSHID:D001244] Off-Label Use[MeSHID:D056687] Term Birth[MeSHID:D047929] Hypertensive disease[MeSHID:D006973] Congenital adrenal hyperplasia[MeSHID:D000312] Disease[MeSHID:D004194] Edema[MeSHID:D004487] treatment failure[MeSHID:D017211] Adrenal Cortical Adenoma[MeSHID:D018246] Hirsutism[MeSHID:D006628] Androgenetic Alopecia[MeSHID:D000505] Hair[MeSHID:D006197] Body Fluids[MeSHID:D001826] Acne Adult[MeSHID:C565791] Growth[MeSHID:D006128] Conn Syndrome[MeSHID:D006929] Coronavirus Infections[MeSHID:D018352] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | inhibitor |
spironolactone | voltage-dependent calcium channel | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Operative Surgical Procedures[MeSHID:D013514] Heart failure[MeSHID:D006333] Heart[MeSHID:D006321] Acne Vulgaris[MeSHID:D000152] Nephrotic Syndrome[MeSHID:D009404] Mental association[MeSHID:D001244] Off-Label Use[MeSHID:D056687] Term Birth[MeSHID:D047929] Hypertensive disease[MeSHID:D006973] Congenital adrenal hyperplasia[MeSHID:D000312] Disease[MeSHID:D004194] Edema[MeSHID:D004487] treatment failure[MeSHID:D017211] Adrenal Cortical Adenoma[MeSHID:D018246] Hirsutism[MeSHID:D006628] Androgenetic Alopecia[MeSHID:D000505] Hair[MeSHID:D006197] Body Fluids[MeSHID:D001826] Acne Adult[MeSHID:C565791] Growth[MeSHID:D006128] Conn Syndrome[MeSHID:D006929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Congestive heart failure[MeSHID:D006333] |
NA | approved | inhibitor |
spironolactone | voltage-dependent calcium channel | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Operative Surgical Procedures[MeSHID:D013514] Heart failure[MeSHID:D006333] Heart[MeSHID:D006321] Acne Vulgaris[MeSHID:D000152] Nephrotic Syndrome[MeSHID:D009404] Mental association[MeSHID:D001244] Off-Label Use[MeSHID:D056687] Term Birth[MeSHID:D047929] Hypertensive disease[MeSHID:D006973] Congenital adrenal hyperplasia[MeSHID:D000312] Disease[MeSHID:D004194] Edema[MeSHID:D004487] treatment failure[MeSHID:D017211] Adrenal Cortical Adenoma[MeSHID:D018246] Hirsutism[MeSHID:D006628] Androgenetic Alopecia[MeSHID:D000505] Hair[MeSHID:D006197] Body Fluids[MeSHID:D001826] Acne Adult[MeSHID:C565791] Growth[MeSHID:D006128] Conn Syndrome[MeSHID:D006929] Coronavirus Infections[MeSHID:D018352] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | inhibitor |
spironolactone | voltage-dependent calcium channel | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Operative Surgical Procedures[MeSHID:D013514] Heart failure[MeSHID:D006333] Heart[MeSHID:D006321] Acne Vulgaris[MeSHID:D000152] Nephrotic Syndrome[MeSHID:D009404] Mental association[MeSHID:D001244] Off-Label Use[MeSHID:D056687] Term Birth[MeSHID:D047929] Hypertensive disease[MeSHID:D006973] Congenital adrenal hyperplasia[MeSHID:D000312] Disease[MeSHID:D004194] Edema[MeSHID:D004487] treatment failure[MeSHID:D017211] Adrenal Cortical Adenoma[MeSHID:D018246] Hirsutism[MeSHID:D006628] Androgenetic Alopecia[MeSHID:D000505] Hair[MeSHID:D006197] Body Fluids[MeSHID:D001826] Acne Adult[MeSHID:C565791] Growth[MeSHID:D006128] Conn Syndrome[MeSHID:D006929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Congestive heart failure[MeSHID:D006333] |
NA | approved | inhibitor |
spironolactone | voltage-dependent calcium channel | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Operative Surgical Procedures[MeSHID:D013514] Heart failure[MeSHID:D006333] Heart[MeSHID:D006321] Acne Vulgaris[MeSHID:D000152] Nephrotic Syndrome[MeSHID:D009404] Mental association[MeSHID:D001244] Off-Label Use[MeSHID:D056687] Term Birth[MeSHID:D047929] Hypertensive disease[MeSHID:D006973] Congenital adrenal hyperplasia[MeSHID:D000312] Disease[MeSHID:D004194] Edema[MeSHID:D004487] treatment failure[MeSHID:D017211] Adrenal Cortical Adenoma[MeSHID:D018246] Hirsutism[MeSHID:D006628] Androgenetic Alopecia[MeSHID:D000505] Hair[MeSHID:D006197] Body Fluids[MeSHID:D001826] Acne Adult[MeSHID:C565791] Growth[MeSHID:D006128] Conn Syndrome[MeSHID:D006929] Coronavirus Infections[MeSHID:D018352] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | inhibitor |
spironolactone | voltage-dependent calcium channel | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Operative Surgical Procedures[MeSHID:D013514] Heart failure[MeSHID:D006333] Heart[MeSHID:D006321] Acne Vulgaris[MeSHID:D000152] Nephrotic Syndrome[MeSHID:D009404] Mental association[MeSHID:D001244] Off-Label Use[MeSHID:D056687] Term Birth[MeSHID:D047929] Hypertensive disease[MeSHID:D006973] Congenital adrenal hyperplasia[MeSHID:D000312] Disease[MeSHID:D004194] Edema[MeSHID:D004487] treatment failure[MeSHID:D017211] Adrenal Cortical Adenoma[MeSHID:D018246] Hirsutism[MeSHID:D006628] Androgenetic Alopecia[MeSHID:D000505] Hair[MeSHID:D006197] Body Fluids[MeSHID:D001826] Acne Adult[MeSHID:C565791] Growth[MeSHID:D006128] Conn Syndrome[MeSHID:D006929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Congestive heart failure[MeSHID:D006333] |
NA | approved | inhibitor |
spironolactone | voltage-dependent calcium channel | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Operative Surgical Procedures[MeSHID:D013514] Heart failure[MeSHID:D006333] Heart[MeSHID:D006321] Acne Vulgaris[MeSHID:D000152] Nephrotic Syndrome[MeSHID:D009404] Mental association[MeSHID:D001244] Off-Label Use[MeSHID:D056687] Term Birth[MeSHID:D047929] Hypertensive disease[MeSHID:D006973] Congenital adrenal hyperplasia[MeSHID:D000312] Disease[MeSHID:D004194] Edema[MeSHID:D004487] treatment failure[MeSHID:D017211] Adrenal Cortical Adenoma[MeSHID:D018246] Hirsutism[MeSHID:D006628] Androgenetic Alopecia[MeSHID:D000505] Hair[MeSHID:D006197] Body Fluids[MeSHID:D001826] Acne Adult[MeSHID:C565791] Growth[MeSHID:D006128] Conn Syndrome[MeSHID:D006929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Congestive heart failure[MeSHID:D006333] |
NA | approved | inhibitor |
spironolactone | voltage-dependent calcium channel | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Operative Surgical Procedures[MeSHID:D013514] Heart failure[MeSHID:D006333] Heart[MeSHID:D006321] Acne Vulgaris[MeSHID:D000152] Nephrotic Syndrome[MeSHID:D009404] Mental association[MeSHID:D001244] Off-Label Use[MeSHID:D056687] Term Birth[MeSHID:D047929] Hypertensive disease[MeSHID:D006973] Congenital adrenal hyperplasia[MeSHID:D000312] Disease[MeSHID:D004194] Edema[MeSHID:D004487] treatment failure[MeSHID:D017211] Adrenal Cortical Adenoma[MeSHID:D018246] Hirsutism[MeSHID:D006628] Androgenetic Alopecia[MeSHID:D000505] Hair[MeSHID:D006197] Body Fluids[MeSHID:D001826] Acne Adult[MeSHID:C565791] Growth[MeSHID:D006128] Conn Syndrome[MeSHID:D006929] Coronavirus Infections[MeSHID:D018352] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | inhibitor |
spironolactone | voltage-dependent calcium channel | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Operative Surgical Procedures[MeSHID:D013514] Heart failure[MeSHID:D006333] Heart[MeSHID:D006321] Acne Vulgaris[MeSHID:D000152] Nephrotic Syndrome[MeSHID:D009404] Mental association[MeSHID:D001244] Off-Label Use[MeSHID:D056687] Term Birth[MeSHID:D047929] Hypertensive disease[MeSHID:D006973] Congenital adrenal hyperplasia[MeSHID:D000312] Disease[MeSHID:D004194] Edema[MeSHID:D004487] treatment failure[MeSHID:D017211] Adrenal Cortical Adenoma[MeSHID:D018246] Hirsutism[MeSHID:D006628] Androgenetic Alopecia[MeSHID:D000505] Hair[MeSHID:D006197] Body Fluids[MeSHID:D001826] Acne Adult[MeSHID:C565791] Growth[MeSHID:D006128] Conn Syndrome[MeSHID:D006929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Congestive heart failure[MeSHID:D006333] |
NA | approved | inhibitor |
spironolactone | voltage-dependent calcium channel | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Operative Surgical Procedures[MeSHID:D013514] Heart failure[MeSHID:D006333] Heart[MeSHID:D006321] Acne Vulgaris[MeSHID:D000152] Nephrotic Syndrome[MeSHID:D009404] Mental association[MeSHID:D001244] Off-Label Use[MeSHID:D056687] Term Birth[MeSHID:D047929] Hypertensive disease[MeSHID:D006973] Congenital adrenal hyperplasia[MeSHID:D000312] Disease[MeSHID:D004194] Edema[MeSHID:D004487] treatment failure[MeSHID:D017211] Adrenal Cortical Adenoma[MeSHID:D018246] Hirsutism[MeSHID:D006628] Androgenetic Alopecia[MeSHID:D000505] Hair[MeSHID:D006197] Body Fluids[MeSHID:D001826] Acne Adult[MeSHID:C565791] Growth[MeSHID:D006128] Conn Syndrome[MeSHID:D006929] Coronavirus Infections[MeSHID:D018352] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | inhibitor |
spironolactone | voltage-dependent calcium channel | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Operative Surgical Procedures[MeSHID:D013514] Heart failure[MeSHID:D006333] Heart[MeSHID:D006321] Acne Vulgaris[MeSHID:D000152] Nephrotic Syndrome[MeSHID:D009404] Mental association[MeSHID:D001244] Off-Label Use[MeSHID:D056687] Term Birth[MeSHID:D047929] Hypertensive disease[MeSHID:D006973] Congenital adrenal hyperplasia[MeSHID:D000312] Disease[MeSHID:D004194] Edema[MeSHID:D004487] treatment failure[MeSHID:D017211] Adrenal Cortical Adenoma[MeSHID:D018246] Hirsutism[MeSHID:D006628] Androgenetic Alopecia[MeSHID:D000505] Hair[MeSHID:D006197] Body Fluids[MeSHID:D001826] Acne Adult[MeSHID:C565791] Growth[MeSHID:D006128] Conn Syndrome[MeSHID:D006929] Coronavirus Infections[MeSHID:D018352] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | inhibitor |
spironolactone | voltage-dependent calcium channel | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Operative Surgical Procedures[MeSHID:D013514] Heart failure[MeSHID:D006333] Heart[MeSHID:D006321] Acne Vulgaris[MeSHID:D000152] Nephrotic Syndrome[MeSHID:D009404] Mental association[MeSHID:D001244] Off-Label Use[MeSHID:D056687] Term Birth[MeSHID:D047929] Hypertensive disease[MeSHID:D006973] Congenital adrenal hyperplasia[MeSHID:D000312] Disease[MeSHID:D004194] Edema[MeSHID:D004487] treatment failure[MeSHID:D017211] Adrenal Cortical Adenoma[MeSHID:D018246] Hirsutism[MeSHID:D006628] Androgenetic Alopecia[MeSHID:D000505] Hair[MeSHID:D006197] Body Fluids[MeSHID:D001826] Acne Adult[MeSHID:C565791] Growth[MeSHID:D006128] Conn Syndrome[MeSHID:D006929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Congestive heart failure[MeSHID:D006333] |
NA | approved | inhibitor |
spironolactone | voltage-dependent calcium channel | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Operative Surgical Procedures[MeSHID:D013514] Heart failure[MeSHID:D006333] Heart[MeSHID:D006321] Acne Vulgaris[MeSHID:D000152] Nephrotic Syndrome[MeSHID:D009404] Mental association[MeSHID:D001244] Off-Label Use[MeSHID:D056687] Term Birth[MeSHID:D047929] Hypertensive disease[MeSHID:D006973] Congenital adrenal hyperplasia[MeSHID:D000312] Disease[MeSHID:D004194] Edema[MeSHID:D004487] treatment failure[MeSHID:D017211] Adrenal Cortical Adenoma[MeSHID:D018246] Hirsutism[MeSHID:D006628] Androgenetic Alopecia[MeSHID:D000505] Hair[MeSHID:D006197] Body Fluids[MeSHID:D001826] Acne Adult[MeSHID:C565791] Growth[MeSHID:D006128] Conn Syndrome[MeSHID:D006929] Coronavirus Infections[MeSHID:D018352] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | inhibitor |
spironolactone | voltage-dependent calcium channel | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Operative Surgical Procedures[MeSHID:D013514] Heart failure[MeSHID:D006333] Heart[MeSHID:D006321] Acne Vulgaris[MeSHID:D000152] Nephrotic Syndrome[MeSHID:D009404] Mental association[MeSHID:D001244] Off-Label Use[MeSHID:D056687] Term Birth[MeSHID:D047929] Hypertensive disease[MeSHID:D006973] Congenital adrenal hyperplasia[MeSHID:D000312] Disease[MeSHID:D004194] Edema[MeSHID:D004487] treatment failure[MeSHID:D017211] Adrenal Cortical Adenoma[MeSHID:D018246] Hirsutism[MeSHID:D006628] Androgenetic Alopecia[MeSHID:D000505] Hair[MeSHID:D006197] Body Fluids[MeSHID:D001826] Acne Adult[MeSHID:C565791] Growth[MeSHID:D006128] Conn Syndrome[MeSHID:D006929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Congestive heart failure[MeSHID:D006333] |
NA | approved | inhibitor |
spironolactone | voltage-dependent calcium channel | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Operative Surgical Procedures[MeSHID:D013514] Heart failure[MeSHID:D006333] Heart[MeSHID:D006321] Acne Vulgaris[MeSHID:D000152] Nephrotic Syndrome[MeSHID:D009404] Mental association[MeSHID:D001244] Off-Label Use[MeSHID:D056687] Term Birth[MeSHID:D047929] Hypertensive disease[MeSHID:D006973] Congenital adrenal hyperplasia[MeSHID:D000312] Disease[MeSHID:D004194] Edema[MeSHID:D004487] treatment failure[MeSHID:D017211] Adrenal Cortical Adenoma[MeSHID:D018246] Hirsutism[MeSHID:D006628] Androgenetic Alopecia[MeSHID:D000505] Hair[MeSHID:D006197] Body Fluids[MeSHID:D001826] Acne Adult[MeSHID:C565791] Growth[MeSHID:D006128] Conn Syndrome[MeSHID:D006929] Coronavirus Infections[MeSHID:D018352] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | inhibitor |
spironolactone | voltage-dependent calcium channel | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Operative Surgical Procedures[MeSHID:D013514] Heart failure[MeSHID:D006333] Heart[MeSHID:D006321] Acne Vulgaris[MeSHID:D000152] Nephrotic Syndrome[MeSHID:D009404] Mental association[MeSHID:D001244] Off-Label Use[MeSHID:D056687] Term Birth[MeSHID:D047929] Hypertensive disease[MeSHID:D006973] Congenital adrenal hyperplasia[MeSHID:D000312] Disease[MeSHID:D004194] Edema[MeSHID:D004487] treatment failure[MeSHID:D017211] Adrenal Cortical Adenoma[MeSHID:D018246] Hirsutism[MeSHID:D006628] Androgenetic Alopecia[MeSHID:D000505] Hair[MeSHID:D006197] Body Fluids[MeSHID:D001826] Acne Adult[MeSHID:C565791] Growth[MeSHID:D006128] Conn Syndrome[MeSHID:D006929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Congestive heart failure[MeSHID:D006333] |
NA | approved | inhibitor |
spironolactone | voltage-dependent calcium channel | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Operative Surgical Procedures[MeSHID:D013514] Heart failure[MeSHID:D006333] Heart[MeSHID:D006321] Acne Vulgaris[MeSHID:D000152] Nephrotic Syndrome[MeSHID:D009404] Mental association[MeSHID:D001244] Off-Label Use[MeSHID:D056687] Term Birth[MeSHID:D047929] Hypertensive disease[MeSHID:D006973] Congenital adrenal hyperplasia[MeSHID:D000312] Disease[MeSHID:D004194] Edema[MeSHID:D004487] treatment failure[MeSHID:D017211] Adrenal Cortical Adenoma[MeSHID:D018246] Hirsutism[MeSHID:D006628] Androgenetic Alopecia[MeSHID:D000505] Hair[MeSHID:D006197] Body Fluids[MeSHID:D001826] Acne Adult[MeSHID:C565791] Growth[MeSHID:D006128] Conn Syndrome[MeSHID:D006929] Coronavirus Infections[MeSHID:D018352] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | inhibitor |
spironolactone | voltage-dependent calcium channel | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Operative Surgical Procedures[MeSHID:D013514] Heart failure[MeSHID:D006333] Heart[MeSHID:D006321] Acne Vulgaris[MeSHID:D000152] Nephrotic Syndrome[MeSHID:D009404] Mental association[MeSHID:D001244] Off-Label Use[MeSHID:D056687] Term Birth[MeSHID:D047929] Hypertensive disease[MeSHID:D006973] Congenital adrenal hyperplasia[MeSHID:D000312] Disease[MeSHID:D004194] Edema[MeSHID:D004487] treatment failure[MeSHID:D017211] Adrenal Cortical Adenoma[MeSHID:D018246] Hirsutism[MeSHID:D006628] Androgenetic Alopecia[MeSHID:D000505] Hair[MeSHID:D006197] Body Fluids[MeSHID:D001826] Acne Adult[MeSHID:C565791] Growth[MeSHID:D006128] Conn Syndrome[MeSHID:D006929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Congestive heart failure[MeSHID:D006333] |
NA | approved | inhibitor |
spironolactone | voltage-dependent calcium channel | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Operative Surgical Procedures[MeSHID:D013514] Heart failure[MeSHID:D006333] Heart[MeSHID:D006321] Acne Vulgaris[MeSHID:D000152] Nephrotic Syndrome[MeSHID:D009404] Mental association[MeSHID:D001244] Off-Label Use[MeSHID:D056687] Term Birth[MeSHID:D047929] Hypertensive disease[MeSHID:D006973] Congenital adrenal hyperplasia[MeSHID:D000312] Disease[MeSHID:D004194] Edema[MeSHID:D004487] treatment failure[MeSHID:D017211] Adrenal Cortical Adenoma[MeSHID:D018246] Hirsutism[MeSHID:D006628] Androgenetic Alopecia[MeSHID:D000505] Hair[MeSHID:D006197] Body Fluids[MeSHID:D001826] Acne Adult[MeSHID:C565791] Growth[MeSHID:D006128] Conn Syndrome[MeSHID:D006929] Coronavirus Infections[MeSHID:D018352] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | inhibitor |
spironolactone | voltage-dependent calcium channel | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Operative Surgical Procedures[MeSHID:D013514] Heart failure[MeSHID:D006333] Heart[MeSHID:D006321] Acne Vulgaris[MeSHID:D000152] Nephrotic Syndrome[MeSHID:D009404] Mental association[MeSHID:D001244] Off-Label Use[MeSHID:D056687] Term Birth[MeSHID:D047929] Hypertensive disease[MeSHID:D006973] Congenital adrenal hyperplasia[MeSHID:D000312] Disease[MeSHID:D004194] Edema[MeSHID:D004487] treatment failure[MeSHID:D017211] Adrenal Cortical Adenoma[MeSHID:D018246] Hirsutism[MeSHID:D006628] Androgenetic Alopecia[MeSHID:D000505] Hair[MeSHID:D006197] Body Fluids[MeSHID:D001826] Acne Adult[MeSHID:C565791] Growth[MeSHID:D006128] Conn Syndrome[MeSHID:D006929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Congestive heart failure[MeSHID:D006333] |
NA | approved | inhibitor |
spironolactone | voltage-dependent calcium channel | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Operative Surgical Procedures[MeSHID:D013514] Heart failure[MeSHID:D006333] Heart[MeSHID:D006321] Acne Vulgaris[MeSHID:D000152] Nephrotic Syndrome[MeSHID:D009404] Mental association[MeSHID:D001244] Off-Label Use[MeSHID:D056687] Term Birth[MeSHID:D047929] Hypertensive disease[MeSHID:D006973] Congenital adrenal hyperplasia[MeSHID:D000312] Disease[MeSHID:D004194] Edema[MeSHID:D004487] treatment failure[MeSHID:D017211] Adrenal Cortical Adenoma[MeSHID:D018246] Hirsutism[MeSHID:D006628] Androgenetic Alopecia[MeSHID:D000505] Hair[MeSHID:D006197] Body Fluids[MeSHID:D001826] Acne Adult[MeSHID:C565791] Growth[MeSHID:D006128] Conn Syndrome[MeSHID:D006929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Congestive heart failure[MeSHID:D006333] |
NA | approved | inhibitor |
spironolactone | voltage-dependent calcium channel | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Operative Surgical Procedures[MeSHID:D013514] Heart failure[MeSHID:D006333] Heart[MeSHID:D006321] Acne Vulgaris[MeSHID:D000152] Nephrotic Syndrome[MeSHID:D009404] Mental association[MeSHID:D001244] Off-Label Use[MeSHID:D056687] Term Birth[MeSHID:D047929] Hypertensive disease[MeSHID:D006973] Congenital adrenal hyperplasia[MeSHID:D000312] Disease[MeSHID:D004194] Edema[MeSHID:D004487] treatment failure[MeSHID:D017211] Adrenal Cortical Adenoma[MeSHID:D018246] Hirsutism[MeSHID:D006628] Androgenetic Alopecia[MeSHID:D000505] Hair[MeSHID:D006197] Body Fluids[MeSHID:D001826] Acne Adult[MeSHID:C565791] Growth[MeSHID:D006128] Conn Syndrome[MeSHID:D006929] Coronavirus Infections[MeSHID:D018352] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | inhibitor |
spironolactone | voltage-dependent calcium channel | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Operative Surgical Procedures[MeSHID:D013514] Heart failure[MeSHID:D006333] Heart[MeSHID:D006321] Acne Vulgaris[MeSHID:D000152] Nephrotic Syndrome[MeSHID:D009404] Mental association[MeSHID:D001244] Off-Label Use[MeSHID:D056687] Term Birth[MeSHID:D047929] Hypertensive disease[MeSHID:D006973] Congenital adrenal hyperplasia[MeSHID:D000312] Disease[MeSHID:D004194] Edema[MeSHID:D004487] treatment failure[MeSHID:D017211] Adrenal Cortical Adenoma[MeSHID:D018246] Hirsutism[MeSHID:D006628] Androgenetic Alopecia[MeSHID:D000505] Hair[MeSHID:D006197] Body Fluids[MeSHID:D001826] Acne Adult[MeSHID:C565791] Growth[MeSHID:D006128] Conn Syndrome[MeSHID:D006929] Coronavirus Infections[MeSHID:D018352] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | inhibitor |
spironolactone | voltage-dependent calcium channel | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Operative Surgical Procedures[MeSHID:D013514] Heart failure[MeSHID:D006333] Heart[MeSHID:D006321] Acne Vulgaris[MeSHID:D000152] Nephrotic Syndrome[MeSHID:D009404] Mental association[MeSHID:D001244] Off-Label Use[MeSHID:D056687] Term Birth[MeSHID:D047929] Hypertensive disease[MeSHID:D006973] Congenital adrenal hyperplasia[MeSHID:D000312] Disease[MeSHID:D004194] Edema[MeSHID:D004487] treatment failure[MeSHID:D017211] Adrenal Cortical Adenoma[MeSHID:D018246] Hirsutism[MeSHID:D006628] Androgenetic Alopecia[MeSHID:D000505] Hair[MeSHID:D006197] Body Fluids[MeSHID:D001826] Acne Adult[MeSHID:C565791] Growth[MeSHID:D006128] Conn Syndrome[MeSHID:D006929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Congestive heart failure[MeSHID:D006333] |
NA | approved | inhibitor |
spironolactone | voltage-dependent calcium channel | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Operative Surgical Procedures[MeSHID:D013514] Heart failure[MeSHID:D006333] Heart[MeSHID:D006321] Acne Vulgaris[MeSHID:D000152] Nephrotic Syndrome[MeSHID:D009404] Mental association[MeSHID:D001244] Off-Label Use[MeSHID:D056687] Term Birth[MeSHID:D047929] Hypertensive disease[MeSHID:D006973] Congenital adrenal hyperplasia[MeSHID:D000312] Disease[MeSHID:D004194] Edema[MeSHID:D004487] treatment failure[MeSHID:D017211] Adrenal Cortical Adenoma[MeSHID:D018246] Hirsutism[MeSHID:D006628] Androgenetic Alopecia[MeSHID:D000505] Hair[MeSHID:D006197] Body Fluids[MeSHID:D001826] Acne Adult[MeSHID:C565791] Growth[MeSHID:D006128] Conn Syndrome[MeSHID:D006929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Congestive heart failure[MeSHID:D006333] |
NA | approved | inhibitor |
spironolactone | voltage-dependent calcium channel | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Operative Surgical Procedures[MeSHID:D013514] Heart failure[MeSHID:D006333] Heart[MeSHID:D006321] Acne Vulgaris[MeSHID:D000152] Nephrotic Syndrome[MeSHID:D009404] Mental association[MeSHID:D001244] Off-Label Use[MeSHID:D056687] Term Birth[MeSHID:D047929] Hypertensive disease[MeSHID:D006973] Congenital adrenal hyperplasia[MeSHID:D000312] Disease[MeSHID:D004194] Edema[MeSHID:D004487] treatment failure[MeSHID:D017211] Adrenal Cortical Adenoma[MeSHID:D018246] Hirsutism[MeSHID:D006628] Androgenetic Alopecia[MeSHID:D000505] Hair[MeSHID:D006197] Body Fluids[MeSHID:D001826] Acne Adult[MeSHID:C565791] Growth[MeSHID:D006128] Conn Syndrome[MeSHID:D006929] Coronavirus Infections[MeSHID:D018352] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | inhibitor |
spironolactone | voltage-dependent calcium channel | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Operative Surgical Procedures[MeSHID:D013514] Heart failure[MeSHID:D006333] Heart[MeSHID:D006321] Acne Vulgaris[MeSHID:D000152] Nephrotic Syndrome[MeSHID:D009404] Mental association[MeSHID:D001244] Off-Label Use[MeSHID:D056687] Term Birth[MeSHID:D047929] Hypertensive disease[MeSHID:D006973] Congenital adrenal hyperplasia[MeSHID:D000312] Disease[MeSHID:D004194] Edema[MeSHID:D004487] treatment failure[MeSHID:D017211] Adrenal Cortical Adenoma[MeSHID:D018246] Hirsutism[MeSHID:D006628] Androgenetic Alopecia[MeSHID:D000505] Hair[MeSHID:D006197] Body Fluids[MeSHID:D001826] Acne Adult[MeSHID:C565791] Growth[MeSHID:D006128] Conn Syndrome[MeSHID:D006929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Congestive heart failure[MeSHID:D006333] |
NA | approved | inhibitor |
spironolactone | voltage-dependent calcium channel | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Operative Surgical Procedures[MeSHID:D013514] Heart failure[MeSHID:D006333] Heart[MeSHID:D006321] Acne Vulgaris[MeSHID:D000152] Nephrotic Syndrome[MeSHID:D009404] Mental association[MeSHID:D001244] Off-Label Use[MeSHID:D056687] Term Birth[MeSHID:D047929] Hypertensive disease[MeSHID:D006973] Congenital adrenal hyperplasia[MeSHID:D000312] Disease[MeSHID:D004194] Edema[MeSHID:D004487] treatment failure[MeSHID:D017211] Adrenal Cortical Adenoma[MeSHID:D018246] Hirsutism[MeSHID:D006628] Androgenetic Alopecia[MeSHID:D000505] Hair[MeSHID:D006197] Body Fluids[MeSHID:D001826] Acne Adult[MeSHID:C565791] Growth[MeSHID:D006128] Conn Syndrome[MeSHID:D006929] Coronavirus Infections[MeSHID:D018352] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | inhibitor |
spironolactone | voltage-dependent calcium channel | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Operative Surgical Procedures[MeSHID:D013514] Heart failure[MeSHID:D006333] Heart[MeSHID:D006321] Acne Vulgaris[MeSHID:D000152] Nephrotic Syndrome[MeSHID:D009404] Mental association[MeSHID:D001244] Off-Label Use[MeSHID:D056687] Term Birth[MeSHID:D047929] Hypertensive disease[MeSHID:D006973] Congenital adrenal hyperplasia[MeSHID:D000312] Disease[MeSHID:D004194] Edema[MeSHID:D004487] treatment failure[MeSHID:D017211] Adrenal Cortical Adenoma[MeSHID:D018246] Hirsutism[MeSHID:D006628] Androgenetic Alopecia[MeSHID:D000505] Hair[MeSHID:D006197] Body Fluids[MeSHID:D001826] Acne Adult[MeSHID:C565791] Growth[MeSHID:D006128] Conn Syndrome[MeSHID:D006929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Congestive heart failure[MeSHID:D006333] |
NA | approved | inhibitor |
spironolactone | voltage-dependent calcium channel | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Operative Surgical Procedures[MeSHID:D013514] Heart failure[MeSHID:D006333] Heart[MeSHID:D006321] Acne Vulgaris[MeSHID:D000152] Nephrotic Syndrome[MeSHID:D009404] Mental association[MeSHID:D001244] Off-Label Use[MeSHID:D056687] Term Birth[MeSHID:D047929] Hypertensive disease[MeSHID:D006973] Congenital adrenal hyperplasia[MeSHID:D000312] Disease[MeSHID:D004194] Edema[MeSHID:D004487] treatment failure[MeSHID:D017211] Adrenal Cortical Adenoma[MeSHID:D018246] Hirsutism[MeSHID:D006628] Androgenetic Alopecia[MeSHID:D000505] Hair[MeSHID:D006197] Body Fluids[MeSHID:D001826] Acne Adult[MeSHID:C565791] Growth[MeSHID:D006128] Conn Syndrome[MeSHID:D006929] Coronavirus Infections[MeSHID:D018352] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | inhibitor |
spironolactone | voltage-dependent calcium channel | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Operative Surgical Procedures[MeSHID:D013514] Heart failure[MeSHID:D006333] Heart[MeSHID:D006321] Acne Vulgaris[MeSHID:D000152] Nephrotic Syndrome[MeSHID:D009404] Mental association[MeSHID:D001244] Off-Label Use[MeSHID:D056687] Term Birth[MeSHID:D047929] Hypertensive disease[MeSHID:D006973] Congenital adrenal hyperplasia[MeSHID:D000312] Disease[MeSHID:D004194] Edema[MeSHID:D004487] treatment failure[MeSHID:D017211] Adrenal Cortical Adenoma[MeSHID:D018246] Hirsutism[MeSHID:D006628] Androgenetic Alopecia[MeSHID:D000505] Hair[MeSHID:D006197] Body Fluids[MeSHID:D001826] Acne Adult[MeSHID:C565791] Growth[MeSHID:D006128] Conn Syndrome[MeSHID:D006929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Congestive heart failure[MeSHID:D006333] |
NA | approved | inhibitor |
spironolactone | voltage-dependent calcium channel | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Operative Surgical Procedures[MeSHID:D013514] Heart failure[MeSHID:D006333] Heart[MeSHID:D006321] Acne Vulgaris[MeSHID:D000152] Nephrotic Syndrome[MeSHID:D009404] Mental association[MeSHID:D001244] Off-Label Use[MeSHID:D056687] Term Birth[MeSHID:D047929] Hypertensive disease[MeSHID:D006973] Congenital adrenal hyperplasia[MeSHID:D000312] Disease[MeSHID:D004194] Edema[MeSHID:D004487] treatment failure[MeSHID:D017211] Adrenal Cortical Adenoma[MeSHID:D018246] Hirsutism[MeSHID:D006628] Androgenetic Alopecia[MeSHID:D000505] Hair[MeSHID:D006197] Body Fluids[MeSHID:D001826] Acne Adult[MeSHID:C565791] Growth[MeSHID:D006128] Conn Syndrome[MeSHID:D006929] Coronavirus Infections[MeSHID:D018352] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | inhibitor |
spironolactone | voltage-dependent calcium channel | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Operative Surgical Procedures[MeSHID:D013514] Heart failure[MeSHID:D006333] Heart[MeSHID:D006321] Acne Vulgaris[MeSHID:D000152] Nephrotic Syndrome[MeSHID:D009404] Mental association[MeSHID:D001244] Off-Label Use[MeSHID:D056687] Term Birth[MeSHID:D047929] Hypertensive disease[MeSHID:D006973] Congenital adrenal hyperplasia[MeSHID:D000312] Disease[MeSHID:D004194] Edema[MeSHID:D004487] treatment failure[MeSHID:D017211] Adrenal Cortical Adenoma[MeSHID:D018246] Hirsutism[MeSHID:D006628] Androgenetic Alopecia[MeSHID:D000505] Hair[MeSHID:D006197] Body Fluids[MeSHID:D001826] Acne Adult[MeSHID:C565791] Growth[MeSHID:D006128] Conn Syndrome[MeSHID:D006929] Coronavirus Infections[MeSHID:D018352] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | inhibitor |
spironolactone | voltage-dependent calcium channel | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Operative Surgical Procedures[MeSHID:D013514] Heart failure[MeSHID:D006333] Heart[MeSHID:D006321] Acne Vulgaris[MeSHID:D000152] Nephrotic Syndrome[MeSHID:D009404] Mental association[MeSHID:D001244] Off-Label Use[MeSHID:D056687] Term Birth[MeSHID:D047929] Hypertensive disease[MeSHID:D006973] Congenital adrenal hyperplasia[MeSHID:D000312] Disease[MeSHID:D004194] Edema[MeSHID:D004487] treatment failure[MeSHID:D017211] Adrenal Cortical Adenoma[MeSHID:D018246] Hirsutism[MeSHID:D006628] Androgenetic Alopecia[MeSHID:D000505] Hair[MeSHID:D006197] Body Fluids[MeSHID:D001826] Acne Adult[MeSHID:C565791] Growth[MeSHID:D006128] Conn Syndrome[MeSHID:D006929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Congestive heart failure[MeSHID:D006333] |
NA | approved | inhibitor |
spironolactone | voltage-dependent calcium channel | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Operative Surgical Procedures[MeSHID:D013514] Heart failure[MeSHID:D006333] Heart[MeSHID:D006321] Acne Vulgaris[MeSHID:D000152] Nephrotic Syndrome[MeSHID:D009404] Mental association[MeSHID:D001244] Off-Label Use[MeSHID:D056687] Term Birth[MeSHID:D047929] Hypertensive disease[MeSHID:D006973] Congenital adrenal hyperplasia[MeSHID:D000312] Disease[MeSHID:D004194] Edema[MeSHID:D004487] treatment failure[MeSHID:D017211] Adrenal Cortical Adenoma[MeSHID:D018246] Hirsutism[MeSHID:D006628] Androgenetic Alopecia[MeSHID:D000505] Hair[MeSHID:D006197] Body Fluids[MeSHID:D001826] Acne Adult[MeSHID:C565791] Growth[MeSHID:D006128] Conn Syndrome[MeSHID:D006929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Congestive heart failure[MeSHID:D006333] |
NA | approved | inhibitor |
spironolactone | voltage-dependent calcium channel | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Operative Surgical Procedures[MeSHID:D013514] Heart failure[MeSHID:D006333] Heart[MeSHID:D006321] Acne Vulgaris[MeSHID:D000152] Nephrotic Syndrome[MeSHID:D009404] Mental association[MeSHID:D001244] Off-Label Use[MeSHID:D056687] Term Birth[MeSHID:D047929] Hypertensive disease[MeSHID:D006973] Congenital adrenal hyperplasia[MeSHID:D000312] Disease[MeSHID:D004194] Edema[MeSHID:D004487] treatment failure[MeSHID:D017211] Adrenal Cortical Adenoma[MeSHID:D018246] Hirsutism[MeSHID:D006628] Androgenetic Alopecia[MeSHID:D000505] Hair[MeSHID:D006197] Body Fluids[MeSHID:D001826] Acne Adult[MeSHID:C565791] Growth[MeSHID:D006128] Conn Syndrome[MeSHID:D006929] Coronavirus Infections[MeSHID:D018352] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | inhibitor |
spironolactone | voltage-dependent calcium channel | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Operative Surgical Procedures[MeSHID:D013514] Heart failure[MeSHID:D006333] Heart[MeSHID:D006321] Acne Vulgaris[MeSHID:D000152] Nephrotic Syndrome[MeSHID:D009404] Mental association[MeSHID:D001244] Off-Label Use[MeSHID:D056687] Term Birth[MeSHID:D047929] Hypertensive disease[MeSHID:D006973] Congenital adrenal hyperplasia[MeSHID:D000312] Disease[MeSHID:D004194] Edema[MeSHID:D004487] treatment failure[MeSHID:D017211] Adrenal Cortical Adenoma[MeSHID:D018246] Hirsutism[MeSHID:D006628] Androgenetic Alopecia[MeSHID:D000505] Hair[MeSHID:D006197] Body Fluids[MeSHID:D001826] Acne Adult[MeSHID:C565791] Growth[MeSHID:D006128] Conn Syndrome[MeSHID:D006929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Congestive heart failure[MeSHID:D006333] |
NA | approved | inhibitor |
spironolactone | voltage-dependent calcium channel | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Operative Surgical Procedures[MeSHID:D013514] Heart failure[MeSHID:D006333] Heart[MeSHID:D006321] Acne Vulgaris[MeSHID:D000152] Nephrotic Syndrome[MeSHID:D009404] Mental association[MeSHID:D001244] Off-Label Use[MeSHID:D056687] Term Birth[MeSHID:D047929] Hypertensive disease[MeSHID:D006973] Congenital adrenal hyperplasia[MeSHID:D000312] Disease[MeSHID:D004194] Edema[MeSHID:D004487] treatment failure[MeSHID:D017211] Adrenal Cortical Adenoma[MeSHID:D018246] Hirsutism[MeSHID:D006628] Androgenetic Alopecia[MeSHID:D000505] Hair[MeSHID:D006197] Body Fluids[MeSHID:D001826] Acne Adult[MeSHID:C565791] Growth[MeSHID:D006128] Conn Syndrome[MeSHID:D006929] Coronavirus Infections[MeSHID:D018352] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | inhibitor |
spironolactone | voltage-dependent calcium channel | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Operative Surgical Procedures[MeSHID:D013514] Heart failure[MeSHID:D006333] Heart[MeSHID:D006321] Acne Vulgaris[MeSHID:D000152] Nephrotic Syndrome[MeSHID:D009404] Mental association[MeSHID:D001244] Off-Label Use[MeSHID:D056687] Term Birth[MeSHID:D047929] Hypertensive disease[MeSHID:D006973] Congenital adrenal hyperplasia[MeSHID:D000312] Disease[MeSHID:D004194] Edema[MeSHID:D004487] treatment failure[MeSHID:D017211] Adrenal Cortical Adenoma[MeSHID:D018246] Hirsutism[MeSHID:D006628] Androgenetic Alopecia[MeSHID:D000505] Hair[MeSHID:D006197] Body Fluids[MeSHID:D001826] Acne Adult[MeSHID:C565791] Growth[MeSHID:D006128] Conn Syndrome[MeSHID:D006929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Congestive heart failure[MeSHID:D006333] |
NA | approved | inhibitor |
spironolactone | voltage-dependent calcium channel | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Operative Surgical Procedures[MeSHID:D013514] Heart failure[MeSHID:D006333] Heart[MeSHID:D006321] Acne Vulgaris[MeSHID:D000152] Nephrotic Syndrome[MeSHID:D009404] Mental association[MeSHID:D001244] Off-Label Use[MeSHID:D056687] Term Birth[MeSHID:D047929] Hypertensive disease[MeSHID:D006973] Congenital adrenal hyperplasia[MeSHID:D000312] Disease[MeSHID:D004194] Edema[MeSHID:D004487] treatment failure[MeSHID:D017211] Adrenal Cortical Adenoma[MeSHID:D018246] Hirsutism[MeSHID:D006628] Androgenetic Alopecia[MeSHID:D000505] Hair[MeSHID:D006197] Body Fluids[MeSHID:D001826] Acne Adult[MeSHID:C565791] Growth[MeSHID:D006128] Conn Syndrome[MeSHID:D006929] Coronavirus Infections[MeSHID:D018352] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | inhibitor |
spironolactone | voltage-dependent calcium channel | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Operative Surgical Procedures[MeSHID:D013514] Heart failure[MeSHID:D006333] Heart[MeSHID:D006321] Acne Vulgaris[MeSHID:D000152] Nephrotic Syndrome[MeSHID:D009404] Mental association[MeSHID:D001244] Off-Label Use[MeSHID:D056687] Term Birth[MeSHID:D047929] Hypertensive disease[MeSHID:D006973] Congenital adrenal hyperplasia[MeSHID:D000312] Disease[MeSHID:D004194] Edema[MeSHID:D004487] treatment failure[MeSHID:D017211] Adrenal Cortical Adenoma[MeSHID:D018246] Hirsutism[MeSHID:D006628] Androgenetic Alopecia[MeSHID:D000505] Hair[MeSHID:D006197] Body Fluids[MeSHID:D001826] Acne Adult[MeSHID:C565791] Growth[MeSHID:D006128] Conn Syndrome[MeSHID:D006929] Coronavirus Infections[MeSHID:D018352] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | inhibitor |
spironolactone | voltage-dependent calcium channel | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Operative Surgical Procedures[MeSHID:D013514] Heart failure[MeSHID:D006333] Heart[MeSHID:D006321] Acne Vulgaris[MeSHID:D000152] Nephrotic Syndrome[MeSHID:D009404] Mental association[MeSHID:D001244] Off-Label Use[MeSHID:D056687] Term Birth[MeSHID:D047929] Hypertensive disease[MeSHID:D006973] Congenital adrenal hyperplasia[MeSHID:D000312] Disease[MeSHID:D004194] Edema[MeSHID:D004487] treatment failure[MeSHID:D017211] Adrenal Cortical Adenoma[MeSHID:D018246] Hirsutism[MeSHID:D006628] Androgenetic Alopecia[MeSHID:D000505] Hair[MeSHID:D006197] Body Fluids[MeSHID:D001826] Acne Adult[MeSHID:C565791] Growth[MeSHID:D006128] Conn Syndrome[MeSHID:D006929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Congestive heart failure[MeSHID:D006333] |
NA | approved | inhibitor |
spironolactone | voltage-dependent calcium channel | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Operative Surgical Procedures[MeSHID:D013514] Heart failure[MeSHID:D006333] Heart[MeSHID:D006321] Acne Vulgaris[MeSHID:D000152] Nephrotic Syndrome[MeSHID:D009404] Mental association[MeSHID:D001244] Off-Label Use[MeSHID:D056687] Term Birth[MeSHID:D047929] Hypertensive disease[MeSHID:D006973] Congenital adrenal hyperplasia[MeSHID:D000312] Disease[MeSHID:D004194] Edema[MeSHID:D004487] treatment failure[MeSHID:D017211] Adrenal Cortical Adenoma[MeSHID:D018246] Hirsutism[MeSHID:D006628] Androgenetic Alopecia[MeSHID:D000505] Hair[MeSHID:D006197] Body Fluids[MeSHID:D001826] Acne Adult[MeSHID:C565791] Growth[MeSHID:D006128] Conn Syndrome[MeSHID:D006929] Coronavirus Infections[MeSHID:D018352] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | inhibitor |
spironolactone | voltage-dependent calcium channel | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Operative Surgical Procedures[MeSHID:D013514] Heart failure[MeSHID:D006333] Heart[MeSHID:D006321] Acne Vulgaris[MeSHID:D000152] Nephrotic Syndrome[MeSHID:D009404] Mental association[MeSHID:D001244] Off-Label Use[MeSHID:D056687] Term Birth[MeSHID:D047929] Hypertensive disease[MeSHID:D006973] Congenital adrenal hyperplasia[MeSHID:D000312] Disease[MeSHID:D004194] Edema[MeSHID:D004487] treatment failure[MeSHID:D017211] Adrenal Cortical Adenoma[MeSHID:D018246] Hirsutism[MeSHID:D006628] Androgenetic Alopecia[MeSHID:D000505] Hair[MeSHID:D006197] Body Fluids[MeSHID:D001826] Acne Adult[MeSHID:C565791] Growth[MeSHID:D006128] Conn Syndrome[MeSHID:D006929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Congestive heart failure[MeSHID:D006333] |
NA | approved | inhibitor |
spironolactone | voltage-dependent calcium channel | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Operative Surgical Procedures[MeSHID:D013514] Heart failure[MeSHID:D006333] Heart[MeSHID:D006321] Acne Vulgaris[MeSHID:D000152] Nephrotic Syndrome[MeSHID:D009404] Mental association[MeSHID:D001244] Off-Label Use[MeSHID:D056687] Term Birth[MeSHID:D047929] Hypertensive disease[MeSHID:D006973] Congenital adrenal hyperplasia[MeSHID:D000312] Disease[MeSHID:D004194] Edema[MeSHID:D004487] treatment failure[MeSHID:D017211] Adrenal Cortical Adenoma[MeSHID:D018246] Hirsutism[MeSHID:D006628] Androgenetic Alopecia[MeSHID:D000505] Hair[MeSHID:D006197] Body Fluids[MeSHID:D001826] Acne Adult[MeSHID:C565791] Growth[MeSHID:D006128] Conn Syndrome[MeSHID:D006929] Coronavirus Infections[MeSHID:D018352] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | inhibitor |
spironolactone | voltage-dependent calcium channel | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Operative Surgical Procedures[MeSHID:D013514] Heart failure[MeSHID:D006333] Heart[MeSHID:D006321] Acne Vulgaris[MeSHID:D000152] Nephrotic Syndrome[MeSHID:D009404] Mental association[MeSHID:D001244] Off-Label Use[MeSHID:D056687] Term Birth[MeSHID:D047929] Hypertensive disease[MeSHID:D006973] Congenital adrenal hyperplasia[MeSHID:D000312] Disease[MeSHID:D004194] Edema[MeSHID:D004487] treatment failure[MeSHID:D017211] Adrenal Cortical Adenoma[MeSHID:D018246] Hirsutism[MeSHID:D006628] Androgenetic Alopecia[MeSHID:D000505] Hair[MeSHID:D006197] Body Fluids[MeSHID:D001826] Acne Adult[MeSHID:C565791] Growth[MeSHID:D006128] Conn Syndrome[MeSHID:D006929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Congestive heart failure[MeSHID:D006333] |
NA | approved | inhibitor |
spironolactone | voltage-dependent calcium channel | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Operative Surgical Procedures[MeSHID:D013514] Heart failure[MeSHID:D006333] Heart[MeSHID:D006321] Acne Vulgaris[MeSHID:D000152] Nephrotic Syndrome[MeSHID:D009404] Mental association[MeSHID:D001244] Off-Label Use[MeSHID:D056687] Term Birth[MeSHID:D047929] Hypertensive disease[MeSHID:D006973] Congenital adrenal hyperplasia[MeSHID:D000312] Disease[MeSHID:D004194] Edema[MeSHID:D004487] treatment failure[MeSHID:D017211] Adrenal Cortical Adenoma[MeSHID:D018246] Hirsutism[MeSHID:D006628] Androgenetic Alopecia[MeSHID:D000505] Hair[MeSHID:D006197] Body Fluids[MeSHID:D001826] Acne Adult[MeSHID:C565791] Growth[MeSHID:D006128] Conn Syndrome[MeSHID:D006929] Coronavirus Infections[MeSHID:D018352] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | inhibitor |
spironolactone | voltage-dependent calcium channel | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Operative Surgical Procedures[MeSHID:D013514] Heart failure[MeSHID:D006333] Heart[MeSHID:D006321] Acne Vulgaris[MeSHID:D000152] Nephrotic Syndrome[MeSHID:D009404] Mental association[MeSHID:D001244] Off-Label Use[MeSHID:D056687] Term Birth[MeSHID:D047929] Hypertensive disease[MeSHID:D006973] Congenital adrenal hyperplasia[MeSHID:D000312] Disease[MeSHID:D004194] Edema[MeSHID:D004487] treatment failure[MeSHID:D017211] Adrenal Cortical Adenoma[MeSHID:D018246] Hirsutism[MeSHID:D006628] Androgenetic Alopecia[MeSHID:D000505] Hair[MeSHID:D006197] Body Fluids[MeSHID:D001826] Acne Adult[MeSHID:C565791] Growth[MeSHID:D006128] Conn Syndrome[MeSHID:D006929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Congestive heart failure[MeSHID:D006333] |
NA | approved | inhibitor |
spironolactone | voltage-dependent calcium channel | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Operative Surgical Procedures[MeSHID:D013514] Heart failure[MeSHID:D006333] Heart[MeSHID:D006321] Acne Vulgaris[MeSHID:D000152] Nephrotic Syndrome[MeSHID:D009404] Mental association[MeSHID:D001244] Off-Label Use[MeSHID:D056687] Term Birth[MeSHID:D047929] Hypertensive disease[MeSHID:D006973] Congenital adrenal hyperplasia[MeSHID:D000312] Disease[MeSHID:D004194] Edema[MeSHID:D004487] treatment failure[MeSHID:D017211] Adrenal Cortical Adenoma[MeSHID:D018246] Hirsutism[MeSHID:D006628] Androgenetic Alopecia[MeSHID:D000505] Hair[MeSHID:D006197] Body Fluids[MeSHID:D001826] Acne Adult[MeSHID:C565791] Growth[MeSHID:D006128] Conn Syndrome[MeSHID:D006929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Congestive heart failure[MeSHID:D006333] |
NA | approved | inhibitor |
spironolactone | voltage-dependent calcium channel | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Operative Surgical Procedures[MeSHID:D013514] Heart failure[MeSHID:D006333] Heart[MeSHID:D006321] Acne Vulgaris[MeSHID:D000152] Nephrotic Syndrome[MeSHID:D009404] Mental association[MeSHID:D001244] Off-Label Use[MeSHID:D056687] Term Birth[MeSHID:D047929] Hypertensive disease[MeSHID:D006973] Congenital adrenal hyperplasia[MeSHID:D000312] Disease[MeSHID:D004194] Edema[MeSHID:D004487] treatment failure[MeSHID:D017211] Adrenal Cortical Adenoma[MeSHID:D018246] Hirsutism[MeSHID:D006628] Androgenetic Alopecia[MeSHID:D000505] Hair[MeSHID:D006197] Body Fluids[MeSHID:D001826] Acne Adult[MeSHID:C565791] Growth[MeSHID:D006128] Conn Syndrome[MeSHID:D006929] Coronavirus Infections[MeSHID:D018352] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | inhibitor |
spironolactone | voltage-dependent calcium channel | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Operative Surgical Procedures[MeSHID:D013514] Heart failure[MeSHID:D006333] Heart[MeSHID:D006321] Acne Vulgaris[MeSHID:D000152] Nephrotic Syndrome[MeSHID:D009404] Mental association[MeSHID:D001244] Off-Label Use[MeSHID:D056687] Term Birth[MeSHID:D047929] Hypertensive disease[MeSHID:D006973] Congenital adrenal hyperplasia[MeSHID:D000312] Disease[MeSHID:D004194] Edema[MeSHID:D004487] treatment failure[MeSHID:D017211] Adrenal Cortical Adenoma[MeSHID:D018246] Hirsutism[MeSHID:D006628] Androgenetic Alopecia[MeSHID:D000505] Hair[MeSHID:D006197] Body Fluids[MeSHID:D001826] Acne Adult[MeSHID:C565791] Growth[MeSHID:D006128] Conn Syndrome[MeSHID:D006929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Congestive heart failure[MeSHID:D006333] |
NA | approved | inhibitor |
spironolactone | voltage-dependent calcium channel | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Operative Surgical Procedures[MeSHID:D013514] Heart failure[MeSHID:D006333] Heart[MeSHID:D006321] Acne Vulgaris[MeSHID:D000152] Nephrotic Syndrome[MeSHID:D009404] Mental association[MeSHID:D001244] Off-Label Use[MeSHID:D056687] Term Birth[MeSHID:D047929] Hypertensive disease[MeSHID:D006973] Congenital adrenal hyperplasia[MeSHID:D000312] Disease[MeSHID:D004194] Edema[MeSHID:D004487] treatment failure[MeSHID:D017211] Adrenal Cortical Adenoma[MeSHID:D018246] Hirsutism[MeSHID:D006628] Androgenetic Alopecia[MeSHID:D000505] Hair[MeSHID:D006197] Body Fluids[MeSHID:D001826] Acne Adult[MeSHID:C565791] Growth[MeSHID:D006128] Conn Syndrome[MeSHID:D006929] Coronavirus Infections[MeSHID:D018352] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | inhibitor |
spironolactone | cytochrome p450 11b2, mitochondrial | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Operative Surgical Procedures[MeSHID:D013514] Heart failure[MeSHID:D006333] Heart[MeSHID:D006321] Acne Vulgaris[MeSHID:D000152] Nephrotic Syndrome[MeSHID:D009404] Mental association[MeSHID:D001244] Off-Label Use[MeSHID:D056687] Term Birth[MeSHID:D047929] Hypertensive disease[MeSHID:D006973] Congenital adrenal hyperplasia[MeSHID:D000312] Disease[MeSHID:D004194] Edema[MeSHID:D004487] treatment failure[MeSHID:D017211] Adrenal Cortical Adenoma[MeSHID:D018246] Hirsutism[MeSHID:D006628] Androgenetic Alopecia[MeSHID:D000505] Hair[MeSHID:D006197] Body Fluids[MeSHID:D001826] Acne Adult[MeSHID:C565791] Growth[MeSHID:D006128] Conn Syndrome[MeSHID:D006929] Coronavirus Infections[MeSHID:D018352] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | antagonist |
spironolactone | cytochrome p450 11b2, mitochondrial | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Operative Surgical Procedures[MeSHID:D013514] Heart failure[MeSHID:D006333] Heart[MeSHID:D006321] Acne Vulgaris[MeSHID:D000152] Nephrotic Syndrome[MeSHID:D009404] Mental association[MeSHID:D001244] Off-Label Use[MeSHID:D056687] Term Birth[MeSHID:D047929] Hypertensive disease[MeSHID:D006973] Congenital adrenal hyperplasia[MeSHID:D000312] Disease[MeSHID:D004194] Edema[MeSHID:D004487] treatment failure[MeSHID:D017211] Adrenal Cortical Adenoma[MeSHID:D018246] Hirsutism[MeSHID:D006628] Androgenetic Alopecia[MeSHID:D000505] Hair[MeSHID:D006197] Body Fluids[MeSHID:D001826] Acne Adult[MeSHID:C565791] Growth[MeSHID:D006128] Conn Syndrome[MeSHID:D006929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Congestive heart failure[MeSHID:D006333] |
NA | approved | antagonist |
spironolactone | steroid 17-alpha-hydroxylase/17,20 lyase | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Operative Surgical Procedures[MeSHID:D013514] Heart failure[MeSHID:D006333] Heart[MeSHID:D006321] Acne Vulgaris[MeSHID:D000152] Nephrotic Syndrome[MeSHID:D009404] Mental association[MeSHID:D001244] Off-Label Use[MeSHID:D056687] Term Birth[MeSHID:D047929] Hypertensive disease[MeSHID:D006973] Congenital adrenal hyperplasia[MeSHID:D000312] Disease[MeSHID:D004194] Edema[MeSHID:D004487] treatment failure[MeSHID:D017211] Adrenal Cortical Adenoma[MeSHID:D018246] Hirsutism[MeSHID:D006628] Androgenetic Alopecia[MeSHID:D000505] Hair[MeSHID:D006197] Body Fluids[MeSHID:D001826] Acne Adult[MeSHID:C565791] Growth[MeSHID:D006128] Conn Syndrome[MeSHID:D006929] Coronavirus Infections[MeSHID:D018352] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | antagonist |
spironolactone | steroid 17-alpha-hydroxylase/17,20 lyase | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Operative Surgical Procedures[MeSHID:D013514] Heart failure[MeSHID:D006333] Heart[MeSHID:D006321] Acne Vulgaris[MeSHID:D000152] Nephrotic Syndrome[MeSHID:D009404] Mental association[MeSHID:D001244] Off-Label Use[MeSHID:D056687] Term Birth[MeSHID:D047929] Hypertensive disease[MeSHID:D006973] Congenital adrenal hyperplasia[MeSHID:D000312] Disease[MeSHID:D004194] Edema[MeSHID:D004487] treatment failure[MeSHID:D017211] Adrenal Cortical Adenoma[MeSHID:D018246] Hirsutism[MeSHID:D006628] Androgenetic Alopecia[MeSHID:D000505] Hair[MeSHID:D006197] Body Fluids[MeSHID:D001826] Acne Adult[MeSHID:C565791] Growth[MeSHID:D006128] Conn Syndrome[MeSHID:D006929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Congestive heart failure[MeSHID:D006333] |
NA | approved | antagonist |
spironolactone | nuclear receptor subfamily 1 group i member 2 | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Operative Surgical Procedures[MeSHID:D013514] Heart failure[MeSHID:D006333] Heart[MeSHID:D006321] Acne Vulgaris[MeSHID:D000152] Nephrotic Syndrome[MeSHID:D009404] Mental association[MeSHID:D001244] Off-Label Use[MeSHID:D056687] Term Birth[MeSHID:D047929] Hypertensive disease[MeSHID:D006973] Congenital adrenal hyperplasia[MeSHID:D000312] Disease[MeSHID:D004194] Edema[MeSHID:D004487] treatment failure[MeSHID:D017211] Adrenal Cortical Adenoma[MeSHID:D018246] Hirsutism[MeSHID:D006628] Androgenetic Alopecia[MeSHID:D000505] Hair[MeSHID:D006197] Body Fluids[MeSHID:D001826] Acne Adult[MeSHID:C565791] Growth[MeSHID:D006128] Conn Syndrome[MeSHID:D006929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Congestive heart failure[MeSHID:D006333] |
0.06 | approved | unknown |
spironolactone | nuclear receptor subfamily 1 group i member 2 | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Operative Surgical Procedures[MeSHID:D013514] Heart failure[MeSHID:D006333] Heart[MeSHID:D006321] Acne Vulgaris[MeSHID:D000152] Nephrotic Syndrome[MeSHID:D009404] Mental association[MeSHID:D001244] Off-Label Use[MeSHID:D056687] Term Birth[MeSHID:D047929] Hypertensive disease[MeSHID:D006973] Congenital adrenal hyperplasia[MeSHID:D000312] Disease[MeSHID:D004194] Edema[MeSHID:D004487] treatment failure[MeSHID:D017211] Adrenal Cortical Adenoma[MeSHID:D018246] Hirsutism[MeSHID:D006628] Androgenetic Alopecia[MeSHID:D000505] Hair[MeSHID:D006197] Body Fluids[MeSHID:D001826] Acne Adult[MeSHID:C565791] Growth[MeSHID:D006128] Conn Syndrome[MeSHID:D006929] Coronavirus Infections[MeSHID:D018352] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.06 | approved | unknown |
spironolactone | glucocorticoid receptor | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Operative Surgical Procedures[MeSHID:D013514] Heart failure[MeSHID:D006333] Heart[MeSHID:D006321] Acne Vulgaris[MeSHID:D000152] Nephrotic Syndrome[MeSHID:D009404] Mental association[MeSHID:D001244] Off-Label Use[MeSHID:D056687] Term Birth[MeSHID:D047929] Hypertensive disease[MeSHID:D006973] Congenital adrenal hyperplasia[MeSHID:D000312] Disease[MeSHID:D004194] Edema[MeSHID:D004487] treatment failure[MeSHID:D017211] Adrenal Cortical Adenoma[MeSHID:D018246] Hirsutism[MeSHID:D006628] Androgenetic Alopecia[MeSHID:D000505] Hair[MeSHID:D006197] Body Fluids[MeSHID:D001826] Acne Adult[MeSHID:C565791] Growth[MeSHID:D006128] Conn Syndrome[MeSHID:D006929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Congestive heart failure[MeSHID:D006333] |
NA | approved | antagonist |
spironolactone | glucocorticoid receptor | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Operative Surgical Procedures[MeSHID:D013514] Heart failure[MeSHID:D006333] Heart[MeSHID:D006321] Acne Vulgaris[MeSHID:D000152] Nephrotic Syndrome[MeSHID:D009404] Mental association[MeSHID:D001244] Off-Label Use[MeSHID:D056687] Term Birth[MeSHID:D047929] Hypertensive disease[MeSHID:D006973] Congenital adrenal hyperplasia[MeSHID:D000312] Disease[MeSHID:D004194] Edema[MeSHID:D004487] treatment failure[MeSHID:D017211] Adrenal Cortical Adenoma[MeSHID:D018246] Hirsutism[MeSHID:D006628] Androgenetic Alopecia[MeSHID:D000505] Hair[MeSHID:D006197] Body Fluids[MeSHID:D001826] Acne Adult[MeSHID:C565791] Growth[MeSHID:D006128] Conn Syndrome[MeSHID:D006929] Coronavirus Infections[MeSHID:D018352] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | antagonist |
spironolactone | mineralocorticoid receptor | small molecule | Successful target | TTD , drugbank , DGIDB | Disease Management[MeSHID:D019468] Operative Surgical Procedures[MeSHID:D013514] Heart failure[MeSHID:D006333] Heart[MeSHID:D006321] Acne Vulgaris[MeSHID:D000152] Nephrotic Syndrome[MeSHID:D009404] Mental association[MeSHID:D001244] Off-Label Use[MeSHID:D056687] Term Birth[MeSHID:D047929] Hypertensive disease[MeSHID:D006973] Congenital adrenal hyperplasia[MeSHID:D000312] Disease[MeSHID:D004194] Edema[MeSHID:D004487] treatment failure[MeSHID:D017211] Adrenal Cortical Adenoma[MeSHID:D018246] Hirsutism[MeSHID:D006628] Androgenetic Alopecia[MeSHID:D000505] Hair[MeSHID:D006197] Body Fluids[MeSHID:D001826] Acne Adult[MeSHID:C565791] Growth[MeSHID:D006128] Conn Syndrome[MeSHID:D006929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Congestive heart failure[MeSHID:D006333] |
1.89 | approved | antagonist |
spironolactone | mineralocorticoid receptor | small molecule | Successful target | TTD , drugbank , DGIDB | Disease Management[MeSHID:D019468] Operative Surgical Procedures[MeSHID:D013514] Heart failure[MeSHID:D006333] Heart[MeSHID:D006321] Acne Vulgaris[MeSHID:D000152] Nephrotic Syndrome[MeSHID:D009404] Mental association[MeSHID:D001244] Off-Label Use[MeSHID:D056687] Term Birth[MeSHID:D047929] Hypertensive disease[MeSHID:D006973] Congenital adrenal hyperplasia[MeSHID:D000312] Disease[MeSHID:D004194] Edema[MeSHID:D004487] treatment failure[MeSHID:D017211] Adrenal Cortical Adenoma[MeSHID:D018246] Hirsutism[MeSHID:D006628] Androgenetic Alopecia[MeSHID:D000505] Hair[MeSHID:D006197] Body Fluids[MeSHID:D001826] Acne Adult[MeSHID:C565791] Growth[MeSHID:D006128] Conn Syndrome[MeSHID:D006929] Coronavirus Infections[MeSHID:D018352] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
1.89 | approved | antagonist |
spironolactone | progesterone receptor | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Operative Surgical Procedures[MeSHID:D013514] Heart failure[MeSHID:D006333] Heart[MeSHID:D006321] Acne Vulgaris[MeSHID:D000152] Nephrotic Syndrome[MeSHID:D009404] Mental association[MeSHID:D001244] Off-Label Use[MeSHID:D056687] Term Birth[MeSHID:D047929] Hypertensive disease[MeSHID:D006973] Congenital adrenal hyperplasia[MeSHID:D000312] Disease[MeSHID:D004194] Edema[MeSHID:D004487] treatment failure[MeSHID:D017211] Adrenal Cortical Adenoma[MeSHID:D018246] Hirsutism[MeSHID:D006628] Androgenetic Alopecia[MeSHID:D000505] Hair[MeSHID:D006197] Body Fluids[MeSHID:D001826] Acne Adult[MeSHID:C565791] Growth[MeSHID:D006128] Conn Syndrome[MeSHID:D006929] Coronavirus Infections[MeSHID:D018352] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | agonist |
spironolactone | progesterone receptor | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Operative Surgical Procedures[MeSHID:D013514] Heart failure[MeSHID:D006333] Heart[MeSHID:D006321] Acne Vulgaris[MeSHID:D000152] Nephrotic Syndrome[MeSHID:D009404] Mental association[MeSHID:D001244] Off-Label Use[MeSHID:D056687] Term Birth[MeSHID:D047929] Hypertensive disease[MeSHID:D006973] Congenital adrenal hyperplasia[MeSHID:D000312] Disease[MeSHID:D004194] Edema[MeSHID:D004487] treatment failure[MeSHID:D017211] Adrenal Cortical Adenoma[MeSHID:D018246] Hirsutism[MeSHID:D006628] Androgenetic Alopecia[MeSHID:D000505] Hair[MeSHID:D006197] Body Fluids[MeSHID:D001826] Acne Adult[MeSHID:C565791] Growth[MeSHID:D006128] Conn Syndrome[MeSHID:D006929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Congestive heart failure[MeSHID:D006333] |
NA | approved | agonist |
spironolactone | sex hormone-binding globulin | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Operative Surgical Procedures[MeSHID:D013514] Heart failure[MeSHID:D006333] Heart[MeSHID:D006321] Acne Vulgaris[MeSHID:D000152] Nephrotic Syndrome[MeSHID:D009404] Mental association[MeSHID:D001244] Off-Label Use[MeSHID:D056687] Term Birth[MeSHID:D047929] Hypertensive disease[MeSHID:D006973] Congenital adrenal hyperplasia[MeSHID:D000312] Disease[MeSHID:D004194] Edema[MeSHID:D004487] treatment failure[MeSHID:D017211] Adrenal Cortical Adenoma[MeSHID:D018246] Hirsutism[MeSHID:D006628] Androgenetic Alopecia[MeSHID:D000505] Hair[MeSHID:D006197] Body Fluids[MeSHID:D001826] Acne Adult[MeSHID:C565791] Growth[MeSHID:D006128] Conn Syndrome[MeSHID:D006929] Coronavirus Infections[MeSHID:D018352] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | binder |
spironolactone | sex hormone-binding globulin | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Operative Surgical Procedures[MeSHID:D013514] Heart failure[MeSHID:D006333] Heart[MeSHID:D006321] Acne Vulgaris[MeSHID:D000152] Nephrotic Syndrome[MeSHID:D009404] Mental association[MeSHID:D001244] Off-Label Use[MeSHID:D056687] Term Birth[MeSHID:D047929] Hypertensive disease[MeSHID:D006973] Congenital adrenal hyperplasia[MeSHID:D000312] Disease[MeSHID:D004194] Edema[MeSHID:D004487] treatment failure[MeSHID:D017211] Adrenal Cortical Adenoma[MeSHID:D018246] Hirsutism[MeSHID:D006628] Androgenetic Alopecia[MeSHID:D000505] Hair[MeSHID:D006197] Body Fluids[MeSHID:D001826] Acne Adult[MeSHID:C565791] Growth[MeSHID:D006128] Conn Syndrome[MeSHID:D006929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Congestive heart failure[MeSHID:D006333] |
NA | approved | binder |
spironolactone | 3-oxo-5-alpha-steroid 4-dehydrogenase | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Operative Surgical Procedures[MeSHID:D013514] Heart failure[MeSHID:D006333] Heart[MeSHID:D006321] Acne Vulgaris[MeSHID:D000152] Nephrotic Syndrome[MeSHID:D009404] Mental association[MeSHID:D001244] Off-Label Use[MeSHID:D056687] Term Birth[MeSHID:D047929] Hypertensive disease[MeSHID:D006973] Congenital adrenal hyperplasia[MeSHID:D000312] Disease[MeSHID:D004194] Edema[MeSHID:D004487] treatment failure[MeSHID:D017211] Adrenal Cortical Adenoma[MeSHID:D018246] Hirsutism[MeSHID:D006628] Androgenetic Alopecia[MeSHID:D000505] Hair[MeSHID:D006197] Body Fluids[MeSHID:D001826] Acne Adult[MeSHID:C565791] Growth[MeSHID:D006128] Conn Syndrome[MeSHID:D006929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Congestive heart failure[MeSHID:D006333] |
NA | approved | antagonist |
spironolactone | 3-oxo-5-alpha-steroid 4-dehydrogenase | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Operative Surgical Procedures[MeSHID:D013514] Heart failure[MeSHID:D006333] Heart[MeSHID:D006321] Acne Vulgaris[MeSHID:D000152] Nephrotic Syndrome[MeSHID:D009404] Mental association[MeSHID:D001244] Off-Label Use[MeSHID:D056687] Term Birth[MeSHID:D047929] Hypertensive disease[MeSHID:D006973] Congenital adrenal hyperplasia[MeSHID:D000312] Disease[MeSHID:D004194] Edema[MeSHID:D004487] treatment failure[MeSHID:D017211] Adrenal Cortical Adenoma[MeSHID:D018246] Hirsutism[MeSHID:D006628] Androgenetic Alopecia[MeSHID:D000505] Hair[MeSHID:D006197] Body Fluids[MeSHID:D001826] Acne Adult[MeSHID:C565791] Growth[MeSHID:D006128] Conn Syndrome[MeSHID:D006929] Coronavirus Infections[MeSHID:D018352] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | antagonist |
spironolactone | 3-oxo-5-alpha-steroid 4-dehydrogenase | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Operative Surgical Procedures[MeSHID:D013514] Heart failure[MeSHID:D006333] Heart[MeSHID:D006321] Acne Vulgaris[MeSHID:D000152] Nephrotic Syndrome[MeSHID:D009404] Mental association[MeSHID:D001244] Off-Label Use[MeSHID:D056687] Term Birth[MeSHID:D047929] Hypertensive disease[MeSHID:D006973] Congenital adrenal hyperplasia[MeSHID:D000312] Disease[MeSHID:D004194] Edema[MeSHID:D004487] treatment failure[MeSHID:D017211] Adrenal Cortical Adenoma[MeSHID:D018246] Hirsutism[MeSHID:D006628] Androgenetic Alopecia[MeSHID:D000505] Hair[MeSHID:D006197] Body Fluids[MeSHID:D001826] Acne Adult[MeSHID:C565791] Growth[MeSHID:D006128] Conn Syndrome[MeSHID:D006929] Coronavirus Infections[MeSHID:D018352] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | antagonist |
spironolactone | 3-oxo-5-alpha-steroid 4-dehydrogenase | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Operative Surgical Procedures[MeSHID:D013514] Heart failure[MeSHID:D006333] Heart[MeSHID:D006321] Acne Vulgaris[MeSHID:D000152] Nephrotic Syndrome[MeSHID:D009404] Mental association[MeSHID:D001244] Off-Label Use[MeSHID:D056687] Term Birth[MeSHID:D047929] Hypertensive disease[MeSHID:D006973] Congenital adrenal hyperplasia[MeSHID:D000312] Disease[MeSHID:D004194] Edema[MeSHID:D004487] treatment failure[MeSHID:D017211] Adrenal Cortical Adenoma[MeSHID:D018246] Hirsutism[MeSHID:D006628] Androgenetic Alopecia[MeSHID:D000505] Hair[MeSHID:D006197] Body Fluids[MeSHID:D001826] Acne Adult[MeSHID:C565791] Growth[MeSHID:D006128] Conn Syndrome[MeSHID:D006929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Congestive heart failure[MeSHID:D006333] |
NA | approved | antagonist |
spironolactone | 3-oxo-5-alpha-steroid 4-dehydrogenase | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Operative Surgical Procedures[MeSHID:D013514] Heart failure[MeSHID:D006333] Heart[MeSHID:D006321] Acne Vulgaris[MeSHID:D000152] Nephrotic Syndrome[MeSHID:D009404] Mental association[MeSHID:D001244] Off-Label Use[MeSHID:D056687] Term Birth[MeSHID:D047929] Hypertensive disease[MeSHID:D006973] Congenital adrenal hyperplasia[MeSHID:D000312] Disease[MeSHID:D004194] Edema[MeSHID:D004487] treatment failure[MeSHID:D017211] Adrenal Cortical Adenoma[MeSHID:D018246] Hirsutism[MeSHID:D006628] Androgenetic Alopecia[MeSHID:D000505] Hair[MeSHID:D006197] Body Fluids[MeSHID:D001826] Acne Adult[MeSHID:C565791] Growth[MeSHID:D006128] Conn Syndrome[MeSHID:D006929] Coronavirus Infections[MeSHID:D018352] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | antagonist |
spironolactone | 3-oxo-5-alpha-steroid 4-dehydrogenase | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Operative Surgical Procedures[MeSHID:D013514] Heart failure[MeSHID:D006333] Heart[MeSHID:D006321] Acne Vulgaris[MeSHID:D000152] Nephrotic Syndrome[MeSHID:D009404] Mental association[MeSHID:D001244] Off-Label Use[MeSHID:D056687] Term Birth[MeSHID:D047929] Hypertensive disease[MeSHID:D006973] Congenital adrenal hyperplasia[MeSHID:D000312] Disease[MeSHID:D004194] Edema[MeSHID:D004487] treatment failure[MeSHID:D017211] Adrenal Cortical Adenoma[MeSHID:D018246] Hirsutism[MeSHID:D006628] Androgenetic Alopecia[MeSHID:D000505] Hair[MeSHID:D006197] Body Fluids[MeSHID:D001826] Acne Adult[MeSHID:C565791] Growth[MeSHID:D006128] Conn Syndrome[MeSHID:D006929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Congestive heart failure[MeSHID:D006333] |
NA | approved | antagonist |
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