Drug-Target Information
Drug Name Target Name Drug Type Target Type Source Drug MeSHID Interaction Score Drug Status Target Action
sparsentan angiotensinogen small molecule NA drugbank Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Hypertensive disease[MeSHID:D006973]
Focal glomerulosclerosis[MeSHID:D005923]
Myocardial Infarction[MeSHID:D009203]		 NA investigational unknown
sparsentan angiotensin ii receptor type-1 NA Successful target TTD , DGIDB Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Hypertensive disease[MeSHID:D006973]
Focal glomerulosclerosis[MeSHID:D005923]
Myocardial Infarction[MeSHID:D009203]		 1.95 phase 3 unknown
sparsentan angiotensin ii receptor type-1 NA Successful target TTD , DGIDB Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Hypertensive disease[MeSHID:D006973]
Focal glomerulosclerosis[MeSHID:D005923]
Myocardial Infarction[MeSHID:D009203]		 1.95 phase 3 antagonist
sparsentan endothelin a receptor NA Successful target TTD , DGIDB Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Hypertensive disease[MeSHID:D006973]
Focal glomerulosclerosis[MeSHID:D005923]
Myocardial Infarction[MeSHID:D009203]		 5.3 phase 3 unknown
sparsentan endothelin a receptor NA Successful target TTD , DGIDB Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Hypertensive disease[MeSHID:D006973]
Focal glomerulosclerosis[MeSHID:D005923]
Myocardial Infarction[MeSHID:D009203]		 5.3 phase 3 antagonist
sparsentan endothelin-1 receptor small molecule NA drugbank , DGIDB Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Hypertensive disease[MeSHID:D006973]
Focal glomerulosclerosis[MeSHID:D005923]
Myocardial Infarction[MeSHID:D009203]		 5.3 investigational unknown
sparsentan endothelin-1 receptor small molecule NA drugbank , DGIDB Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Hypertensive disease[MeSHID:D006973]
Focal glomerulosclerosis[MeSHID:D005923]
Myocardial Infarction[MeSHID:D009203]		 5.3 investigational antagonist
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