Drug-Target Information | ||||||||
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Drug Name | Target Name | Drug Type | Target Type | Source | Drug MeSHID | Interaction Score | Drug Status | Target Action |
sertraline | sigma receptor | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Depressive disorder[MeSHID:D003866] Premature Ejaculation[MeSHID:D061686] Fibromyalgia[MeSHID:D005356] Mental Depression[MeSHID:D003863] Post-Traumatic Stress Disorder[MeSHID:D013313] Vasovagal syncope[MeSHID:D019462] Phobia Social[MeSHID:D000072861] Cerebrovascular accident[MeSHID:D020521] Panic Disorder[MeSHID:D016584] Obsessive compulsive behavior[MeSHID:D003192] Premenstrual Dysphoric Disorder[MeSHID:D065446] Anxiety Disorders[MeSHID:D001008] Obsessive-Compulsive Disorder[MeSHID:D009771] Diabetic Neuropathies[MeSHID:D003929] Migraine Disorders[MeSHID:D008881] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | inhibitor,binder |
sertraline | sigma receptor | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Depressive disorder[MeSHID:D003866] Premature Ejaculation[MeSHID:D061686] Fibromyalgia[MeSHID:D005356] Mental Depression[MeSHID:D003863] Post-Traumatic Stress Disorder[MeSHID:D013313] Vasovagal syncope[MeSHID:D019462] Phobia Social[MeSHID:D000072861] Cerebrovascular accident[MeSHID:D020521] Panic Disorder[MeSHID:D016584] Obsessive compulsive behavior[MeSHID:D003192] Premenstrual Dysphoric Disorder[MeSHID:D065446] Anxiety Disorders[MeSHID:D001008] Obsessive-Compulsive Disorder[MeSHID:D009771] Diabetic Neuropathies[MeSHID:D003929] Migraine Disorders[MeSHID:D008881] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | inhibitor,binder |
sertraline | equilibrative nucleoside transporter 4 | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Depressive disorder[MeSHID:D003866] Premature Ejaculation[MeSHID:D061686] Fibromyalgia[MeSHID:D005356] Mental Depression[MeSHID:D003863] Post-Traumatic Stress Disorder[MeSHID:D013313] Vasovagal syncope[MeSHID:D019462] Phobia Social[MeSHID:D000072861] Cerebrovascular accident[MeSHID:D020521] Panic Disorder[MeSHID:D016584] Obsessive compulsive behavior[MeSHID:D003192] Premenstrual Dysphoric Disorder[MeSHID:D065446] Anxiety Disorders[MeSHID:D001008] Obsessive-Compulsive Disorder[MeSHID:D009771] Diabetic Neuropathies[MeSHID:D003929] Migraine Disorders[MeSHID:D008881] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | unknown |
sertraline | sodium-dependent noradrenaline transporter | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Depressive disorder[MeSHID:D003866] Premature Ejaculation[MeSHID:D061686] Fibromyalgia[MeSHID:D005356] Mental Depression[MeSHID:D003863] Post-Traumatic Stress Disorder[MeSHID:D013313] Vasovagal syncope[MeSHID:D019462] Phobia Social[MeSHID:D000072861] Cerebrovascular accident[MeSHID:D020521] Panic Disorder[MeSHID:D016584] Obsessive compulsive behavior[MeSHID:D003192] Premenstrual Dysphoric Disorder[MeSHID:D065446] Anxiety Disorders[MeSHID:D001008] Obsessive-Compulsive Disorder[MeSHID:D009771] Diabetic Neuropathies[MeSHID:D003929] Migraine Disorders[MeSHID:D008881] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | inhibitor,downregulator |
sertraline | sodium-dependent dopamine transporter | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Depressive disorder[MeSHID:D003866] Premature Ejaculation[MeSHID:D061686] Fibromyalgia[MeSHID:D005356] Mental Depression[MeSHID:D003863] Post-Traumatic Stress Disorder[MeSHID:D013313] Vasovagal syncope[MeSHID:D019462] Phobia Social[MeSHID:D000072861] Cerebrovascular accident[MeSHID:D020521] Panic Disorder[MeSHID:D016584] Obsessive compulsive behavior[MeSHID:D003192] Premenstrual Dysphoric Disorder[MeSHID:D065446] Anxiety Disorders[MeSHID:D001008] Obsessive-Compulsive Disorder[MeSHID:D009771] Diabetic Neuropathies[MeSHID:D003929] Migraine Disorders[MeSHID:D008881] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.3 | approved | inhibitor,binder |
sertraline | serotonin transporter | NA | Successful target | TTD , DGIDB | Disease Management[MeSHID:D019468] Depressive disorder[MeSHID:D003866] Premature Ejaculation[MeSHID:D061686] Fibromyalgia[MeSHID:D005356] Mental Depression[MeSHID:D003863] Post-Traumatic Stress Disorder[MeSHID:D013313] Vasovagal syncope[MeSHID:D019462] Phobia Social[MeSHID:D000072861] Cerebrovascular accident[MeSHID:D020521] Panic Disorder[MeSHID:D016584] Obsessive compulsive behavior[MeSHID:D003192] Premenstrual Dysphoric Disorder[MeSHID:D065446] Anxiety Disorders[MeSHID:D001008] Obsessive-Compulsive Disorder[MeSHID:D009771] Diabetic Neuropathies[MeSHID:D003929] Migraine Disorders[MeSHID:D008881] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.67 | approved | unknown |
sertraline | serotonin transporter | NA | Successful target | TTD , DGIDB | Disease Management[MeSHID:D019468] Depressive disorder[MeSHID:D003866] Premature Ejaculation[MeSHID:D061686] Fibromyalgia[MeSHID:D005356] Mental Depression[MeSHID:D003863] Post-Traumatic Stress Disorder[MeSHID:D013313] Vasovagal syncope[MeSHID:D019462] Phobia Social[MeSHID:D000072861] Cerebrovascular accident[MeSHID:D020521] Panic Disorder[MeSHID:D016584] Obsessive compulsive behavior[MeSHID:D003192] Premenstrual Dysphoric Disorder[MeSHID:D065446] Anxiety Disorders[MeSHID:D001008] Obsessive-Compulsive Disorder[MeSHID:D009771] Diabetic Neuropathies[MeSHID:D003929] Migraine Disorders[MeSHID:D008881] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.67 | approved | inhibitor |
sertraline | sodium-dependent serotonin transporter | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Depressive disorder[MeSHID:D003866] Premature Ejaculation[MeSHID:D061686] Fibromyalgia[MeSHID:D005356] Mental Depression[MeSHID:D003863] Post-Traumatic Stress Disorder[MeSHID:D013313] Vasovagal syncope[MeSHID:D019462] Phobia Social[MeSHID:D000072861] Cerebrovascular accident[MeSHID:D020521] Panic Disorder[MeSHID:D016584] Obsessive compulsive behavior[MeSHID:D003192] Premenstrual Dysphoric Disorder[MeSHID:D065446] Anxiety Disorders[MeSHID:D001008] Obsessive-Compulsive Disorder[MeSHID:D009771] Diabetic Neuropathies[MeSHID:D003929] Migraine Disorders[MeSHID:D008881] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.67 | approved | inhibitor,binder,downregulator |
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