Drug-Target Information
Drug Name Target Name Drug Type Target Type Source Drug MeSHID Interaction Score Drug Status Target Action
sertraline sigma receptor small molecule NA drugbank Disease Management[MeSHID:D019468]
Depressive disorder[MeSHID:D003866]
Premature Ejaculation[MeSHID:D061686]
Fibromyalgia[MeSHID:D005356]
Mental Depression[MeSHID:D003863]
Post-Traumatic Stress Disorder[MeSHID:D013313]
Vasovagal syncope[MeSHID:D019462]
Phobia
Social[MeSHID:D000072861]
Cerebrovascular accident[MeSHID:D020521]
Panic Disorder[MeSHID:D016584]
Obsessive compulsive behavior[MeSHID:D003192]
Premenstrual Dysphoric Disorder[MeSHID:D065446]
Anxiety Disorders[MeSHID:D001008]
Obsessive-Compulsive Disorder[MeSHID:D009771]
Diabetic Neuropathies[MeSHID:D003929]
Migraine Disorders[MeSHID:D008881]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
NA approved inhibitor,binder
sertraline sigma receptor small molecule NA drugbank Disease Management[MeSHID:D019468]
Depressive disorder[MeSHID:D003866]
Premature Ejaculation[MeSHID:D061686]
Fibromyalgia[MeSHID:D005356]
Mental Depression[MeSHID:D003863]
Post-Traumatic Stress Disorder[MeSHID:D013313]
Vasovagal syncope[MeSHID:D019462]
Phobia
Social[MeSHID:D000072861]
Cerebrovascular accident[MeSHID:D020521]
Panic Disorder[MeSHID:D016584]
Obsessive compulsive behavior[MeSHID:D003192]
Premenstrual Dysphoric Disorder[MeSHID:D065446]
Anxiety Disorders[MeSHID:D001008]
Obsessive-Compulsive Disorder[MeSHID:D009771]
Diabetic Neuropathies[MeSHID:D003929]
Migraine Disorders[MeSHID:D008881]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
NA approved inhibitor,binder
sertraline equilibrative nucleoside transporter 4 small molecule NA drugbank Disease Management[MeSHID:D019468]
Depressive disorder[MeSHID:D003866]
Premature Ejaculation[MeSHID:D061686]
Fibromyalgia[MeSHID:D005356]
Mental Depression[MeSHID:D003863]
Post-Traumatic Stress Disorder[MeSHID:D013313]
Vasovagal syncope[MeSHID:D019462]
Phobia
Social[MeSHID:D000072861]
Cerebrovascular accident[MeSHID:D020521]
Panic Disorder[MeSHID:D016584]
Obsessive compulsive behavior[MeSHID:D003192]
Premenstrual Dysphoric Disorder[MeSHID:D065446]
Anxiety Disorders[MeSHID:D001008]
Obsessive-Compulsive Disorder[MeSHID:D009771]
Diabetic Neuropathies[MeSHID:D003929]
Migraine Disorders[MeSHID:D008881]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
NA approved unknown
sertraline sodium-dependent noradrenaline transporter small molecule NA drugbank Disease Management[MeSHID:D019468]
Depressive disorder[MeSHID:D003866]
Premature Ejaculation[MeSHID:D061686]
Fibromyalgia[MeSHID:D005356]
Mental Depression[MeSHID:D003863]
Post-Traumatic Stress Disorder[MeSHID:D013313]
Vasovagal syncope[MeSHID:D019462]
Phobia
Social[MeSHID:D000072861]
Cerebrovascular accident[MeSHID:D020521]
Panic Disorder[MeSHID:D016584]
Obsessive compulsive behavior[MeSHID:D003192]
Premenstrual Dysphoric Disorder[MeSHID:D065446]
Anxiety Disorders[MeSHID:D001008]
Obsessive-Compulsive Disorder[MeSHID:D009771]
Diabetic Neuropathies[MeSHID:D003929]
Migraine Disorders[MeSHID:D008881]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
NA approved inhibitor,downregulator
sertraline sodium-dependent dopamine transporter small molecule NA drugbank , DGIDB Disease Management[MeSHID:D019468]
Depressive disorder[MeSHID:D003866]
Premature Ejaculation[MeSHID:D061686]
Fibromyalgia[MeSHID:D005356]
Mental Depression[MeSHID:D003863]
Post-Traumatic Stress Disorder[MeSHID:D013313]
Vasovagal syncope[MeSHID:D019462]
Phobia
Social[MeSHID:D000072861]
Cerebrovascular accident[MeSHID:D020521]
Panic Disorder[MeSHID:D016584]
Obsessive compulsive behavior[MeSHID:D003192]
Premenstrual Dysphoric Disorder[MeSHID:D065446]
Anxiety Disorders[MeSHID:D001008]
Obsessive-Compulsive Disorder[MeSHID:D009771]
Diabetic Neuropathies[MeSHID:D003929]
Migraine Disorders[MeSHID:D008881]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
0.3 approved inhibitor,binder
sertraline serotonin transporter NA Successful target TTD , DGIDB Disease Management[MeSHID:D019468]
Depressive disorder[MeSHID:D003866]
Premature Ejaculation[MeSHID:D061686]
Fibromyalgia[MeSHID:D005356]
Mental Depression[MeSHID:D003863]
Post-Traumatic Stress Disorder[MeSHID:D013313]
Vasovagal syncope[MeSHID:D019462]
Phobia
Social[MeSHID:D000072861]
Cerebrovascular accident[MeSHID:D020521]
Panic Disorder[MeSHID:D016584]
Obsessive compulsive behavior[MeSHID:D003192]
Premenstrual Dysphoric Disorder[MeSHID:D065446]
Anxiety Disorders[MeSHID:D001008]
Obsessive-Compulsive Disorder[MeSHID:D009771]
Diabetic Neuropathies[MeSHID:D003929]
Migraine Disorders[MeSHID:D008881]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
0.67 approved unknown
sertraline serotonin transporter NA Successful target TTD , DGIDB Disease Management[MeSHID:D019468]
Depressive disorder[MeSHID:D003866]
Premature Ejaculation[MeSHID:D061686]
Fibromyalgia[MeSHID:D005356]
Mental Depression[MeSHID:D003863]
Post-Traumatic Stress Disorder[MeSHID:D013313]
Vasovagal syncope[MeSHID:D019462]
Phobia
Social[MeSHID:D000072861]
Cerebrovascular accident[MeSHID:D020521]
Panic Disorder[MeSHID:D016584]
Obsessive compulsive behavior[MeSHID:D003192]
Premenstrual Dysphoric Disorder[MeSHID:D065446]
Anxiety Disorders[MeSHID:D001008]
Obsessive-Compulsive Disorder[MeSHID:D009771]
Diabetic Neuropathies[MeSHID:D003929]
Migraine Disorders[MeSHID:D008881]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
0.67 approved inhibitor
sertraline sodium-dependent serotonin transporter small molecule NA drugbank , DGIDB Disease Management[MeSHID:D019468]
Depressive disorder[MeSHID:D003866]
Premature Ejaculation[MeSHID:D061686]
Fibromyalgia[MeSHID:D005356]
Mental Depression[MeSHID:D003863]
Post-Traumatic Stress Disorder[MeSHID:D013313]
Vasovagal syncope[MeSHID:D019462]
Phobia
Social[MeSHID:D000072861]
Cerebrovascular accident[MeSHID:D020521]
Panic Disorder[MeSHID:D016584]
Obsessive compulsive behavior[MeSHID:D003192]
Premenstrual Dysphoric Disorder[MeSHID:D065446]
Anxiety Disorders[MeSHID:D001008]
Obsessive-Compulsive Disorder[MeSHID:D009771]
Diabetic Neuropathies[MeSHID:D003929]
Migraine Disorders[MeSHID:D008881]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
0.67 approved inhibitor,binder,downregulator
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