| Drug-Target Information | ||||||||
|---|---|---|---|---|---|---|---|---|
| Drug Name | Target Name | Drug Type | Target Type | Source | Drug MeSHID | Interaction Score | Drug Status | Target Action |
| selpercatinib | fibroblast growth factor receptor 1 | small molecule | NA | drugbank | Medullary carcinoma of thyroid[MeSHID:C536914] Thyroid carcinoma[MeSHID:D013964] Radioactivity[MeSHID:D011851] Non-Small Cell Lung Carcinoma[MeSHID:D002289] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Malignant tumor of colon[MeSHID:D003110] |
NA | approved,investigational | inhibitor |
| selpercatinib | fibroblast growth factor receptor 2 | small molecule | NA | drugbank | Medullary carcinoma of thyroid[MeSHID:C536914] Thyroid carcinoma[MeSHID:D013964] Radioactivity[MeSHID:D011851] Non-Small Cell Lung Carcinoma[MeSHID:D002289] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Malignant tumor of colon[MeSHID:D003110] |
NA | approved,investigational | inhibitor |
| selpercatinib | fibroblast growth factor receptor 3 | small molecule | NA | drugbank | Medullary carcinoma of thyroid[MeSHID:C536914] Thyroid carcinoma[MeSHID:D013964] Radioactivity[MeSHID:D011851] Non-Small Cell Lung Carcinoma[MeSHID:D002289] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Malignant tumor of colon[MeSHID:D003110] |
NA | approved,investigational | inhibitor |
| selpercatinib | vascular endothelial growth factor receptor 1 | small molecule | NA | drugbank | Medullary carcinoma of thyroid[MeSHID:C536914] Thyroid carcinoma[MeSHID:D013964] Radioactivity[MeSHID:D011851] Non-Small Cell Lung Carcinoma[MeSHID:D002289] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Malignant tumor of colon[MeSHID:D003110] |
NA | approved,investigational | inhibitor |
| selpercatinib | vascular endothelial growth factor receptor 3 | small molecule | NA | drugbank | Medullary carcinoma of thyroid[MeSHID:C536914] Thyroid carcinoma[MeSHID:D013964] Radioactivity[MeSHID:D011851] Non-Small Cell Lung Carcinoma[MeSHID:D002289] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Malignant tumor of colon[MeSHID:D003110] |
NA | approved,investigational | inhibitor |
| selpercatinib | proto-oncogene c-ret | NA | Successful target | TTD , DGIDB | Medullary carcinoma of thyroid[MeSHID:C536914] Thyroid carcinoma[MeSHID:D013964] Radioactivity[MeSHID:D011851] Non-Small Cell Lung Carcinoma[MeSHID:D002289] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Malignant tumor of colon[MeSHID:D003110] |
NA | approved | unknown |
| selpercatinib | proto-oncogene tyrosine-protein kinase receptor ret | small molecule | NA | drugbank , DGIDB | Medullary carcinoma of thyroid[MeSHID:C536914] Thyroid carcinoma[MeSHID:D013964] Radioactivity[MeSHID:D011851] Non-Small Cell Lung Carcinoma[MeSHID:D002289] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Malignant tumor of colon[MeSHID:D003110] |
NA | approved,investigational | inhibitor |
| selpercatinib | proto-oncogene c-ret | NA | Successful target | TTD , DGIDB | Medullary carcinoma of thyroid[MeSHID:C536914] Thyroid carcinoma[MeSHID:D013964] Radioactivity[MeSHID:D011851] Non-Small Cell Lung Carcinoma[MeSHID:D002289] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Malignant tumor of colon[MeSHID:D003110] |
NA | approved | inhibitor |
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