Drug-Target Information | ||||||||
---|---|---|---|---|---|---|---|---|
Drug Name | Target Name | Drug Type | Target Type | Source | Drug MeSHID | Interaction Score | Drug Status | Target Action |
rosuvastatin | hmg-coa reductase | NA | Successful target | TTD , DGIDB | Homozygote[MeSHID:D006720] Diabetes Mellitus[MeSHID:D003920] Cardiovascular Diseases[MeSHID:D002318] Arteriosclerosis[MeSHID:D001161] Atherosclerosis[MeSHID:D050197] Stable angina[MeSHID:D060050] Coronary artery[MeSHID:D003331] Myocardial Infarction[MeSHID:D009203] Dyslipidemias[MeSHID:D050171] Hypercholesterolemia Familial[MeSHID:D006938] Coronary Arteriosclerosis[MeSHID:D003324] Hypercholesterolemia[MeSHID:D006937] Prescription of drug (procedure)[MeSHID:D011307] Disease[MeSHID:D004194] Diet therapy[MeSHID:D004035] Coronary heart disease[MeSHID:D003327] Acute Coronary Syndrome[MeSHID:D054058] Peripheral Arterial Diseases[MeSHID:D058729] Cerebrovascular accident[MeSHID:D020521] Hyperlipoproteinemia Type III[MeSHID:D006952] Chronic Kidney Diseases[MeSHID:D051436] Aortic Aneurysm Abdominal[MeSHID:D017544] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
2.94 | approved | unknown |
rosuvastatin | 3-hydroxy-3-methylglutaryl-coenzyme a reductase | small molecule | NA | drugbank , DGIDB | Homozygote[MeSHID:D006720] Diabetes Mellitus[MeSHID:D003920] Cardiovascular Diseases[MeSHID:D002318] Arteriosclerosis[MeSHID:D001161] Atherosclerosis[MeSHID:D050197] Stable angina[MeSHID:D060050] Coronary artery[MeSHID:D003331] Myocardial Infarction[MeSHID:D009203] Dyslipidemias[MeSHID:D050171] Hypercholesterolemia Familial[MeSHID:D006938] Coronary Arteriosclerosis[MeSHID:D003324] Hypercholesterolemia[MeSHID:D006937] Prescription of drug (procedure)[MeSHID:D011307] Disease[MeSHID:D004194] Diet therapy[MeSHID:D004035] Coronary heart disease[MeSHID:D003327] Acute Coronary Syndrome[MeSHID:D054058] Peripheral Arterial Diseases[MeSHID:D058729] Cerebrovascular accident[MeSHID:D020521] Hyperlipoproteinemia Type III[MeSHID:D006952] Chronic Kidney Diseases[MeSHID:D051436] Aortic Aneurysm Abdominal[MeSHID:D017544] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
2.94 | approved | inhibitor |
rosuvastatin | hmg-coa reductase | NA | Successful target | TTD , DGIDB | Homozygote[MeSHID:D006720] Diabetes Mellitus[MeSHID:D003920] Cardiovascular Diseases[MeSHID:D002318] Arteriosclerosis[MeSHID:D001161] Atherosclerosis[MeSHID:D050197] Stable angina[MeSHID:D060050] Coronary artery[MeSHID:D003331] Myocardial Infarction[MeSHID:D009203] Dyslipidemias[MeSHID:D050171] Hypercholesterolemia Familial[MeSHID:D006938] Coronary Arteriosclerosis[MeSHID:D003324] Hypercholesterolemia[MeSHID:D006937] Prescription of drug (procedure)[MeSHID:D011307] Disease[MeSHID:D004194] Diet therapy[MeSHID:D004035] Coronary heart disease[MeSHID:D003327] Acute Coronary Syndrome[MeSHID:D054058] Peripheral Arterial Diseases[MeSHID:D058729] Cerebrovascular accident[MeSHID:D020521] Hyperlipoproteinemia Type III[MeSHID:D006952] Chronic Kidney Diseases[MeSHID:D051436] Aortic Aneurysm Abdominal[MeSHID:D017544] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
2.94 | approved | inhibitor |
rosuvastatin | integrin alpha-l | small molecule | NA | drugbank | Homozygote[MeSHID:D006720] Diabetes Mellitus[MeSHID:D003920] Cardiovascular Diseases[MeSHID:D002318] Arteriosclerosis[MeSHID:D001161] Atherosclerosis[MeSHID:D050197] Stable angina[MeSHID:D060050] Coronary artery[MeSHID:D003331] Myocardial Infarction[MeSHID:D009203] Dyslipidemias[MeSHID:D050171] Hypercholesterolemia Familial[MeSHID:D006938] Coronary Arteriosclerosis[MeSHID:D003324] Hypercholesterolemia[MeSHID:D006937] Prescription of drug (procedure)[MeSHID:D011307] Disease[MeSHID:D004194] Diet therapy[MeSHID:D004035] Coronary heart disease[MeSHID:D003327] Acute Coronary Syndrome[MeSHID:D054058] Peripheral Arterial Diseases[MeSHID:D058729] Cerebrovascular accident[MeSHID:D020521] Hyperlipoproteinemia Type III[MeSHID:D006952] Chronic Kidney Diseases[MeSHID:D051436] Aortic Aneurysm Abdominal[MeSHID:D017544] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | inhibitory allosteric modulator |
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