| Drug-Target Information | ||||||||
|---|---|---|---|---|---|---|---|---|
| Drug Name | Target Name | Drug Type | Target Type | Source | Drug MeSHID | Interaction Score | Drug Status | Target Action |
| ritanserin | voltage-gated calcium channel alpha cav2.2 | NA | Successful target | TTD | Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Anxiety Disorders[MeSHID:D001008] |
NA | discontinued in phase 3 | unknown |
| ritanserin | 5-hydroxytryptamine receptor 2a | small molecule | NA | drugbank , DGIDB | Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Anxiety Disorders[MeSHID:D001008] |
0.04 | investigational | inverse agonist,antagonist |
| ritanserin | 5-ht 2a receptor | NA | Successful target | TTD , DGIDB | Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Anxiety Disorders[MeSHID:D001008] |
0.04 | discontinued in phase 3 | antagonist |
| ritanserin | 5-ht 2b receptor | NA | Successful target | TTD , DGIDB | Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Anxiety Disorders[MeSHID:D001008] |
0.04 | discontinued in phase 3 | antagonist |
| ritanserin | 5-ht 2c receptor | NA | Successful target | TTD , DGIDB | Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Anxiety Disorders[MeSHID:D001008] |
0.03 | discontinued in phase 3 | antagonist |
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