| Drug-Target Information | ||||||||
|---|---|---|---|---|---|---|---|---|
| Drug Name | Target Name | Drug Type | Target Type | Source | Drug MeSHID | Interaction Score | Drug Status | Target Action |
| risperidone | alpha-1a adrenergic receptor | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Schizophrenia[MeSHID:D012559] Irritable Mood[MeSHID:D007508] Bipolar Disorder[MeSHID:D001714] Disease[MeSHID:D004194] Aggressive behavior[MeSHID:D000374] Autistic Disorder[MeSHID:D001321] Off-Label Use[MeSHID:D056687] Depressive Disorder Treatment-Resistant[MeSHID:D061218] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.07 | approved,investigational | antagonist |
| risperidone | alpha-1b adrenergic receptor | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Schizophrenia[MeSHID:D012559] Irritable Mood[MeSHID:D007508] Bipolar Disorder[MeSHID:D001714] Disease[MeSHID:D004194] Aggressive behavior[MeSHID:D000374] Autistic Disorder[MeSHID:D001321] Off-Label Use[MeSHID:D056687] Depressive Disorder Treatment-Resistant[MeSHID:D061218] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.1 | approved,investigational | antagonist |
| risperidone | alpha-2b adrenergic receptor | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Schizophrenia[MeSHID:D012559] Irritable Mood[MeSHID:D007508] Bipolar Disorder[MeSHID:D001714] Disease[MeSHID:D004194] Aggressive behavior[MeSHID:D000374] Autistic Disorder[MeSHID:D001321] Off-Label Use[MeSHID:D056687] Depressive Disorder Treatment-Resistant[MeSHID:D061218] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | antagonist |
| risperidone | alpha-2c adrenergic receptor | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Schizophrenia[MeSHID:D012559] Irritable Mood[MeSHID:D007508] Bipolar Disorder[MeSHID:D001714] Disease[MeSHID:D004194] Aggressive behavior[MeSHID:D000374] Autistic Disorder[MeSHID:D001321] Off-Label Use[MeSHID:D056687] Depressive Disorder Treatment-Resistant[MeSHID:D061218] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | antagonist |
| risperidone | dopamine d1 receptor | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Schizophrenia[MeSHID:D012559] Irritable Mood[MeSHID:D007508] Bipolar Disorder[MeSHID:D001714] Disease[MeSHID:D004194] Aggressive behavior[MeSHID:D000374] Autistic Disorder[MeSHID:D001321] Off-Label Use[MeSHID:D056687] Depressive Disorder Treatment-Resistant[MeSHID:D061218] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | antagonist |
| risperidone | dopamine d2 receptor | small molecule | Successful target | TTD , drugbank , DGIDB | Disease Management[MeSHID:D019468] Schizophrenia[MeSHID:D012559] Irritable Mood[MeSHID:D007508] Bipolar Disorder[MeSHID:D001714] Disease[MeSHID:D004194] Aggressive behavior[MeSHID:D000374] Autistic Disorder[MeSHID:D001321] Off-Label Use[MeSHID:D056687] Depressive Disorder Treatment-Resistant[MeSHID:D061218] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.37 | approved,investigational | antagonist |
| risperidone | histamine h1 receptor | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Schizophrenia[MeSHID:D012559] Irritable Mood[MeSHID:D007508] Bipolar Disorder[MeSHID:D001714] Disease[MeSHID:D004194] Aggressive behavior[MeSHID:D000374] Autistic Disorder[MeSHID:D001321] Off-Label Use[MeSHID:D056687] Depressive Disorder Treatment-Resistant[MeSHID:D061218] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.03 | approved,investigational | antagonist |
| risperidone | 5-hydroxytryptamine receptor 1a | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Schizophrenia[MeSHID:D012559] Irritable Mood[MeSHID:D007508] Bipolar Disorder[MeSHID:D001714] Disease[MeSHID:D004194] Aggressive behavior[MeSHID:D000374] Autistic Disorder[MeSHID:D001321] Off-Label Use[MeSHID:D056687] Depressive Disorder Treatment-Resistant[MeSHID:D061218] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.04 | approved,investigational | antagonist |
| risperidone | 5-hydroxytryptamine receptor 1d | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Schizophrenia[MeSHID:D012559] Irritable Mood[MeSHID:D007508] Bipolar Disorder[MeSHID:D001714] Disease[MeSHID:D004194] Aggressive behavior[MeSHID:D000374] Autistic Disorder[MeSHID:D001321] Off-Label Use[MeSHID:D056687] Depressive Disorder Treatment-Resistant[MeSHID:D061218] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.03 | approved,investigational | antagonist |
| risperidone | 5-hydroxytryptamine receptor 2a | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Schizophrenia[MeSHID:D012559] Irritable Mood[MeSHID:D007508] Bipolar Disorder[MeSHID:D001714] Disease[MeSHID:D004194] Aggressive behavior[MeSHID:D000374] Autistic Disorder[MeSHID:D001321] Off-Label Use[MeSHID:D056687] Depressive Disorder Treatment-Resistant[MeSHID:D061218] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.1 | approved,investigational | antagonist |
| risperidone | 5-hydroxytryptamine receptor 2c | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Schizophrenia[MeSHID:D012559] Irritable Mood[MeSHID:D007508] Bipolar Disorder[MeSHID:D001714] Disease[MeSHID:D004194] Aggressive behavior[MeSHID:D000374] Autistic Disorder[MeSHID:D001321] Off-Label Use[MeSHID:D056687] Depressive Disorder Treatment-Resistant[MeSHID:D061218] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.18 | approved,investigational | antagonist |
| risperidone | 5-hydroxytryptamine receptor 7 | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Schizophrenia[MeSHID:D012559] Irritable Mood[MeSHID:D007508] Bipolar Disorder[MeSHID:D001714] Disease[MeSHID:D004194] Aggressive behavior[MeSHID:D000374] Autistic Disorder[MeSHID:D001321] Off-Label Use[MeSHID:D056687] Depressive Disorder Treatment-Resistant[MeSHID:D061218] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.04 | approved,investigational | antagonist |
| risperidone | d(2l) dopamine receptor | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Schizophrenia[MeSHID:D012559] Irritable Mood[MeSHID:D007508] Bipolar Disorder[MeSHID:D001714] Disease[MeSHID:D004194] Aggressive behavior[MeSHID:D000374] Autistic Disorder[MeSHID:D001321] Off-Label Use[MeSHID:D056687] Depressive Disorder Treatment-Resistant[MeSHID:D061218] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | antagonist |
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