Drug-Target Information
Drug Name Target Name Drug Type Target Type Source Drug MeSHID Interaction Score Drug Status Target Action
ripretinib serine/threonine-protein kinase b-raf small molecule NA drugbank Diagnosis[MeSHID:D003933]
Gastrointestinal Stromal Tumors[MeSHID:D046152]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Glioma[MeSHID:D005910]
Malignant Neoplasms[MeSHID:D009369]
Mastocytosis
Systemic[MeSHID:D034721]		 NA approved inhibitor
ripretinib vascular endothelial growth factor receptor 2 small molecule NA drugbank Diagnosis[MeSHID:D003933]
Gastrointestinal Stromal Tumors[MeSHID:D046152]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Glioma[MeSHID:D005910]
Malignant Neoplasms[MeSHID:D009369]
Mastocytosis
Systemic[MeSHID:D034721]		 NA approved inhibitor
ripretinib tyrosine-protein kinase kit NA Successful target TTD , DGIDB Diagnosis[MeSHID:D003933]
Gastrointestinal Stromal Tumors[MeSHID:D046152]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Glioma[MeSHID:D005910]
Malignant Neoplasms[MeSHID:D009369]
Mastocytosis
Systemic[MeSHID:D034721]		 2.21 approved inhibitor
ripretinib mast/stem cell growth factor receptor kit small molecule NA drugbank , DGIDB Diagnosis[MeSHID:D003933]
Gastrointestinal Stromal Tumors[MeSHID:D046152]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Glioma[MeSHID:D005910]
Malignant Neoplasms[MeSHID:D009369]
Mastocytosis
Systemic[MeSHID:D034721]		 2.21 approved inhibitor
ripretinib platelet-derived growth factor receptor alpha small molecule Successful target TTD , drugbank Diagnosis[MeSHID:D003933]
Gastrointestinal Stromal Tumors[MeSHID:D046152]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Glioma[MeSHID:D005910]
Malignant Neoplasms[MeSHID:D009369]
Mastocytosis
Systemic[MeSHID:D034721]		 NA approved inhibitor
ripretinib platelet-derived growth factor receptor beta small molecule NA drugbank Diagnosis[MeSHID:D003933]
Gastrointestinal Stromal Tumors[MeSHID:D046152]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Glioma[MeSHID:D005910]
Malignant Neoplasms[MeSHID:D009369]
Mastocytosis
Systemic[MeSHID:D034721]		 NA approved inhibitor
ripretinib angiopoietin-1 receptor small molecule NA drugbank Diagnosis[MeSHID:D003933]
Gastrointestinal Stromal Tumors[MeSHID:D046152]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Glioma[MeSHID:D005910]
Malignant Neoplasms[MeSHID:D009369]
Mastocytosis
Systemic[MeSHID:D034721]		 NA approved inhibitor
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