Drug-Target Information
Drug Name Target Name Drug Type Target Type Source Drug MeSHID Interaction Score Drug Status Target Action
riociguat guanylate cyclase soluble subunit alpha-2 small molecule NA drugbank , DGIDB Familial primary pulmonary hypertension[MeSHID:D065627]
Operative Surgical Procedures[MeSHID:D013514]
Connective Tissue Diseases[MeSHID:D003240]
Pulmonary Hypertension[MeSHID:D006976]
Recurrence (disease attribute)[MeSHID:D012008]
Idiopathic pulmonary arterial hypertension[MeSHID:D065627]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 7.27 approved agonist,stimulator,positive modulator
riociguat guanylate cyclase soluble subunit alpha-2 small molecule NA drugbank , DGIDB Familial primary pulmonary hypertension[MeSHID:D065627]
Operative Surgical Procedures[MeSHID:D013514]
Connective Tissue Diseases[MeSHID:D003240]
Pulmonary Hypertension[MeSHID:D006976]
Recurrence (disease attribute)[MeSHID:D012008]
Idiopathic pulmonary arterial hypertension[MeSHID:D065627]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 7.27 approved agonist,stimulator
riociguat soluble guanylyl cyclase NA Successful target TTD , DGIDB Familial primary pulmonary hypertension[MeSHID:D065627]
Operative Surgical Procedures[MeSHID:D013514]
Connective Tissue Diseases[MeSHID:D003240]
Pulmonary Hypertension[MeSHID:D006976]
Recurrence (disease attribute)[MeSHID:D012008]
Idiopathic pulmonary arterial hypertension[MeSHID:D065627]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 6.37 approved unknown
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