| Drug-Target Information | ||||||||
|---|---|---|---|---|---|---|---|---|
| Drug Name | Target Name | Drug Type | Target Type | Source | Drug MeSHID | Interaction Score | Drug Status | Target Action |
| regorafenib | tyrosine-protein kinase abl1 | small molecule | NA | drugbank , DGIDB | Liver carcinoma[MeSHID:D006528] Gastrointestinal Stromal Tumors[MeSHID:D046152] Neoplasm Metastasis[MeSHID:D009362] Colorectal Cancer[MeSHID:D015179] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.03 | approved | inhibitor |
| regorafenib | serine/threonine-protein kinase b-raf | small molecule | NA | drugbank , DGIDB | Liver carcinoma[MeSHID:D006528] Gastrointestinal Stromal Tumors[MeSHID:D046152] Neoplasm Metastasis[MeSHID:D009362] Colorectal Cancer[MeSHID:D015179] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.19 | approved | inhibitor |
| regorafenib | discoidin domain-containing receptor 2 | small molecule | NA | drugbank , DGIDB | Liver carcinoma[MeSHID:D006528] Gastrointestinal Stromal Tumors[MeSHID:D046152] Neoplasm Metastasis[MeSHID:D009362] Colorectal Cancer[MeSHID:D015179] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.57 | approved | inhibitor |
| regorafenib | ephrin type-a receptor 2 | small molecule | NA | drugbank , DGIDB | Liver carcinoma[MeSHID:D006528] Gastrointestinal Stromal Tumors[MeSHID:D046152] Neoplasm Metastasis[MeSHID:D009362] Colorectal Cancer[MeSHID:D015179] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.13 | approved | inhibitor |
| regorafenib | fibroblast growth factor receptor 1 | small molecule | NA | drugbank , DGIDB | Liver carcinoma[MeSHID:D006528] Gastrointestinal Stromal Tumors[MeSHID:D046152] Neoplasm Metastasis[MeSHID:D009362] Colorectal Cancer[MeSHID:D015179] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.05 | approved | inhibitor |
| regorafenib | fibroblast growth factor receptor 2 | small molecule | NA | drugbank , DGIDB | Liver carcinoma[MeSHID:D006528] Gastrointestinal Stromal Tumors[MeSHID:D046152] Neoplasm Metastasis[MeSHID:D009362] Colorectal Cancer[MeSHID:D015179] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.09 | approved | inhibitor |
| regorafenib | vascular endothelial growth factor receptor 1 | small molecule | NA | drugbank , DGIDB | Liver carcinoma[MeSHID:D006528] Gastrointestinal Stromal Tumors[MeSHID:D046152] Neoplasm Metastasis[MeSHID:D009362] Colorectal Cancer[MeSHID:D015179] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.11 | approved | inhibitor |
| regorafenib | vascular endothelial growth factor receptor 3 | small molecule | NA | drugbank , DGIDB | Liver carcinoma[MeSHID:D006528] Gastrointestinal Stromal Tumors[MeSHID:D046152] Neoplasm Metastasis[MeSHID:D009362] Colorectal Cancer[MeSHID:D015179] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.1 | approved | inhibitor |
| regorafenib | tyrosine-protein kinase frk | small molecule | NA | drugbank , DGIDB | Liver carcinoma[MeSHID:D006528] Gastrointestinal Stromal Tumors[MeSHID:D046152] Neoplasm Metastasis[MeSHID:D009362] Colorectal Cancer[MeSHID:D015179] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.16 | approved | inhibitor |
| regorafenib | vascular endothelial growth factor receptor 2 | small molecule | Successful target | TTD , drugbank , DGIDB | Liver carcinoma[MeSHID:D006528] Gastrointestinal Stromal Tumors[MeSHID:D046152] Neoplasm Metastasis[MeSHID:D009362] Colorectal Cancer[MeSHID:D015179] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.15 | approved | inhibitor |
| regorafenib | mast/stem cell growth factor receptor kit | small molecule | NA | drugbank , DGIDB | Liver carcinoma[MeSHID:D006528] Gastrointestinal Stromal Tumors[MeSHID:D046152] Neoplasm Metastasis[MeSHID:D009362] Colorectal Cancer[MeSHID:D015179] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.35 | approved | inhibitor |
| regorafenib | tyrosine-protein kinase kit | NA | Successful target | TTD , DGIDB | Liver carcinoma[MeSHID:D006528] Gastrointestinal Stromal Tumors[MeSHID:D046152] Neoplasm Metastasis[MeSHID:D009362] Colorectal Cancer[MeSHID:D015179] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.35 | approved | unknown |
| regorafenib | tyrosine-protein kinase kit | NA | Successful target | TTD , DGIDB | Liver carcinoma[MeSHID:D006528] Gastrointestinal Stromal Tumors[MeSHID:D046152] Neoplasm Metastasis[MeSHID:D009362] Colorectal Cancer[MeSHID:D015179] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.35 | approved | inhibitor |
| regorafenib | mitogen-activated protein kinase 11 | small molecule | NA | drugbank , DGIDB | Liver carcinoma[MeSHID:D006528] Gastrointestinal Stromal Tumors[MeSHID:D046152] Neoplasm Metastasis[MeSHID:D009362] Colorectal Cancer[MeSHID:D015179] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.17 | approved | inhibitor |
| regorafenib | high affinity nerve growth factor receptor | small molecule | NA | drugbank , DGIDB | Liver carcinoma[MeSHID:D006528] Gastrointestinal Stromal Tumors[MeSHID:D046152] Neoplasm Metastasis[MeSHID:D009362] Colorectal Cancer[MeSHID:D015179] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.04 | approved | inhibitor |
| regorafenib | platelet-derived growth factor receptor alpha | small molecule | NA | drugbank , DGIDB | Liver carcinoma[MeSHID:D006528] Gastrointestinal Stromal Tumors[MeSHID:D046152] Neoplasm Metastasis[MeSHID:D009362] Colorectal Cancer[MeSHID:D015179] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.14 | approved | inhibitor |
| regorafenib | platelet-derived growth factor receptor beta | small molecule | NA | drugbank , DGIDB | Liver carcinoma[MeSHID:D006528] Gastrointestinal Stromal Tumors[MeSHID:D046152] Neoplasm Metastasis[MeSHID:D009362] Colorectal Cancer[MeSHID:D015179] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.12 | approved | inhibitor |
| regorafenib | raf proto-oncogene serine/threonine-protein kinase | small molecule | NA | drugbank , DGIDB | Liver carcinoma[MeSHID:D006528] Gastrointestinal Stromal Tumors[MeSHID:D046152] Neoplasm Metastasis[MeSHID:D009362] Colorectal Cancer[MeSHID:D015179] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.26 | approved | inhibitor |
| regorafenib | proto-oncogene tyrosine-protein kinase receptor ret | small molecule | NA | drugbank , DGIDB | Liver carcinoma[MeSHID:D006528] Gastrointestinal Stromal Tumors[MeSHID:D046152] Neoplasm Metastasis[MeSHID:D009362] Colorectal Cancer[MeSHID:D015179] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.24 | approved | inhibitor |
| regorafenib | proto-oncogene c-ret | NA | Successful target | TTD , DGIDB | Liver carcinoma[MeSHID:D006528] Gastrointestinal Stromal Tumors[MeSHID:D046152] Neoplasm Metastasis[MeSHID:D009362] Colorectal Cancer[MeSHID:D015179] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.24 | approved | unknown |
| regorafenib | proto-oncogene c-ret | NA | Successful target | TTD , DGIDB | Liver carcinoma[MeSHID:D006528] Gastrointestinal Stromal Tumors[MeSHID:D046152] Neoplasm Metastasis[MeSHID:D009362] Colorectal Cancer[MeSHID:D015179] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.24 | approved | inhibitor |
| regorafenib | angiopoietin-1 receptor | small molecule | NA | drugbank , DGIDB | Liver carcinoma[MeSHID:D006528] Gastrointestinal Stromal Tumors[MeSHID:D046152] Neoplasm Metastasis[MeSHID:D009362] Colorectal Cancer[MeSHID:D015179] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.51 | approved | inhibitor |
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