| Drug-Target Information | ||||||||
|---|---|---|---|---|---|---|---|---|
| Drug Name | Target Name | Drug Type | Target Type | Source | Drug MeSHID | Interaction Score | Drug Status | Target Action |
| ranolazine | alpha-1 adrenergic receptors | small molecule | NA | drugbank | Cardiac Arrhythmia[MeSHID:D001145] Acute Coronary Syndrome[MeSHID:D054058] Blood Platelets[MeSHID:D001792] Angina Pectoris[MeSHID:D000787] Heart[MeSHID:D006321] Tachycardia Ventricular[MeSHID:D017180] Off-Label Use[MeSHID:D056687] Stable angina[MeSHID:D060050] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Atrial Fibrillation[MeSHID:D001281] |
NA | approved,investigational | antagonist |
| ranolazine | alpha-1 adrenergic receptors | small molecule | NA | drugbank | Cardiac Arrhythmia[MeSHID:D001145] Acute Coronary Syndrome[MeSHID:D054058] Blood Platelets[MeSHID:D001792] Angina Pectoris[MeSHID:D000787] Heart[MeSHID:D006321] Tachycardia Ventricular[MeSHID:D017180] Off-Label Use[MeSHID:D056687] Stable angina[MeSHID:D060050] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Atrial Fibrillation[MeSHID:D001281] |
NA | approved,investigational | antagonist |
| ranolazine | alpha-1 adrenergic receptors | small molecule | NA | drugbank | Cardiac Arrhythmia[MeSHID:D001145] Acute Coronary Syndrome[MeSHID:D054058] Blood Platelets[MeSHID:D001792] Angina Pectoris[MeSHID:D000787] Heart[MeSHID:D006321] Tachycardia Ventricular[MeSHID:D017180] Off-Label Use[MeSHID:D056687] Stable angina[MeSHID:D060050] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Atrial Fibrillation[MeSHID:D001281] |
NA | approved,investigational | antagonist |
| ranolazine | beta-1 adrenergic receptor | small molecule | NA | drugbank | Cardiac Arrhythmia[MeSHID:D001145] Acute Coronary Syndrome[MeSHID:D054058] Blood Platelets[MeSHID:D001792] Angina Pectoris[MeSHID:D000787] Heart[MeSHID:D006321] Tachycardia Ventricular[MeSHID:D017180] Off-Label Use[MeSHID:D056687] Stable angina[MeSHID:D060050] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Atrial Fibrillation[MeSHID:D001281] |
NA | approved,investigational | antagonist |
| ranolazine | voltage gated l-type calcium channel | small molecule | NA | drugbank | Cardiac Arrhythmia[MeSHID:D001145] Acute Coronary Syndrome[MeSHID:D054058] Blood Platelets[MeSHID:D001792] Angina Pectoris[MeSHID:D000787] Heart[MeSHID:D006321] Tachycardia Ventricular[MeSHID:D017180] Off-Label Use[MeSHID:D056687] Stable angina[MeSHID:D060050] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Atrial Fibrillation[MeSHID:D001281] |
NA | approved,investigational | inhibitor |
| ranolazine | voltage gated l-type calcium channel | small molecule | NA | drugbank | Cardiac Arrhythmia[MeSHID:D001145] Acute Coronary Syndrome[MeSHID:D054058] Blood Platelets[MeSHID:D001792] Angina Pectoris[MeSHID:D000787] Heart[MeSHID:D006321] Tachycardia Ventricular[MeSHID:D017180] Off-Label Use[MeSHID:D056687] Stable angina[MeSHID:D060050] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Atrial Fibrillation[MeSHID:D001281] |
NA | approved,investigational | inhibitor |
| ranolazine | voltage gated l-type calcium channel | small molecule | NA | drugbank | Cardiac Arrhythmia[MeSHID:D001145] Acute Coronary Syndrome[MeSHID:D054058] Blood Platelets[MeSHID:D001792] Angina Pectoris[MeSHID:D000787] Heart[MeSHID:D006321] Tachycardia Ventricular[MeSHID:D017180] Off-Label Use[MeSHID:D056687] Stable angina[MeSHID:D060050] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Atrial Fibrillation[MeSHID:D001281] |
NA | approved,investigational | inhibitor |
| ranolazine | voltage gated l-type calcium channel | small molecule | NA | drugbank | Cardiac Arrhythmia[MeSHID:D001145] Acute Coronary Syndrome[MeSHID:D054058] Blood Platelets[MeSHID:D001792] Angina Pectoris[MeSHID:D000787] Heart[MeSHID:D006321] Tachycardia Ventricular[MeSHID:D017180] Off-Label Use[MeSHID:D056687] Stable angina[MeSHID:D060050] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Atrial Fibrillation[MeSHID:D001281] |
NA | approved,investigational | inhibitor |
| ranolazine | voltage gated l-type calcium channel | small molecule | NA | drugbank | Cardiac Arrhythmia[MeSHID:D001145] Acute Coronary Syndrome[MeSHID:D054058] Blood Platelets[MeSHID:D001792] Angina Pectoris[MeSHID:D000787] Heart[MeSHID:D006321] Tachycardia Ventricular[MeSHID:D017180] Off-Label Use[MeSHID:D056687] Stable angina[MeSHID:D060050] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Atrial Fibrillation[MeSHID:D001281] |
NA | approved,investigational | inhibitor |
| ranolazine | voltage gated l-type calcium channel | small molecule | NA | drugbank | Cardiac Arrhythmia[MeSHID:D001145] Acute Coronary Syndrome[MeSHID:D054058] Blood Platelets[MeSHID:D001792] Angina Pectoris[MeSHID:D000787] Heart[MeSHID:D006321] Tachycardia Ventricular[MeSHID:D017180] Off-Label Use[MeSHID:D056687] Stable angina[MeSHID:D060050] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Atrial Fibrillation[MeSHID:D001281] |
NA | approved,investigational | inhibitor |
| ranolazine | voltage gated l-type calcium channel | small molecule | NA | drugbank | Cardiac Arrhythmia[MeSHID:D001145] Acute Coronary Syndrome[MeSHID:D054058] Blood Platelets[MeSHID:D001792] Angina Pectoris[MeSHID:D000787] Heart[MeSHID:D006321] Tachycardia Ventricular[MeSHID:D017180] Off-Label Use[MeSHID:D056687] Stable angina[MeSHID:D060050] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Atrial Fibrillation[MeSHID:D001281] |
NA | approved,investigational | inhibitor |
| ranolazine | voltage gated l-type calcium channel | small molecule | NA | drugbank | Cardiac Arrhythmia[MeSHID:D001145] Acute Coronary Syndrome[MeSHID:D054058] Blood Platelets[MeSHID:D001792] Angina Pectoris[MeSHID:D000787] Heart[MeSHID:D006321] Tachycardia Ventricular[MeSHID:D017180] Off-Label Use[MeSHID:D056687] Stable angina[MeSHID:D060050] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Atrial Fibrillation[MeSHID:D001281] |
NA | approved,investigational | inhibitor |
| ranolazine | inward rectifier potassium channel | small molecule | NA | drugbank | Cardiac Arrhythmia[MeSHID:D001145] Acute Coronary Syndrome[MeSHID:D054058] Blood Platelets[MeSHID:D001792] Angina Pectoris[MeSHID:D000787] Heart[MeSHID:D006321] Tachycardia Ventricular[MeSHID:D017180] Off-Label Use[MeSHID:D056687] Stable angina[MeSHID:D060050] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Atrial Fibrillation[MeSHID:D001281] |
NA | approved,investigational | inhibitor |
| ranolazine | inward rectifier potassium channel | small molecule | NA | drugbank | Cardiac Arrhythmia[MeSHID:D001145] Acute Coronary Syndrome[MeSHID:D054058] Blood Platelets[MeSHID:D001792] Angina Pectoris[MeSHID:D000787] Heart[MeSHID:D006321] Tachycardia Ventricular[MeSHID:D017180] Off-Label Use[MeSHID:D056687] Stable angina[MeSHID:D060050] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Atrial Fibrillation[MeSHID:D001281] |
NA | approved,investigational | inhibitor |
| ranolazine | inward rectifier potassium channel | small molecule | NA | drugbank | Cardiac Arrhythmia[MeSHID:D001145] Acute Coronary Syndrome[MeSHID:D054058] Blood Platelets[MeSHID:D001792] Angina Pectoris[MeSHID:D000787] Heart[MeSHID:D006321] Tachycardia Ventricular[MeSHID:D017180] Off-Label Use[MeSHID:D056687] Stable angina[MeSHID:D060050] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Atrial Fibrillation[MeSHID:D001281] |
NA | approved,investigational | inhibitor |
| ranolazine | inward rectifier potassium channel | small molecule | NA | drugbank | Cardiac Arrhythmia[MeSHID:D001145] Acute Coronary Syndrome[MeSHID:D054058] Blood Platelets[MeSHID:D001792] Angina Pectoris[MeSHID:D000787] Heart[MeSHID:D006321] Tachycardia Ventricular[MeSHID:D017180] Off-Label Use[MeSHID:D056687] Stable angina[MeSHID:D060050] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Atrial Fibrillation[MeSHID:D001281] |
NA | approved,investigational | inhibitor |
| ranolazine | plasminogen | NA | Successful target | TTD , DGIDB | Cardiac Arrhythmia[MeSHID:D001145] Acute Coronary Syndrome[MeSHID:D054058] Blood Platelets[MeSHID:D001792] Angina Pectoris[MeSHID:D000787] Heart[MeSHID:D006321] Tachycardia Ventricular[MeSHID:D017180] Off-Label Use[MeSHID:D056687] Stable angina[MeSHID:D060050] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Atrial Fibrillation[MeSHID:D001281] |
0.31 | approved | unknown |
| ranolazine | sodium channel protein | small molecule | NA | drugbank | Cardiac Arrhythmia[MeSHID:D001145] Acute Coronary Syndrome[MeSHID:D054058] Blood Platelets[MeSHID:D001792] Angina Pectoris[MeSHID:D000787] Heart[MeSHID:D006321] Tachycardia Ventricular[MeSHID:D017180] Off-Label Use[MeSHID:D056687] Stable angina[MeSHID:D060050] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Atrial Fibrillation[MeSHID:D001281] |
NA | approved,investigational | inhibitor |
| ranolazine | sodium channel protein | small molecule | NA | drugbank | Cardiac Arrhythmia[MeSHID:D001145] Acute Coronary Syndrome[MeSHID:D054058] Blood Platelets[MeSHID:D001792] Angina Pectoris[MeSHID:D000787] Heart[MeSHID:D006321] Tachycardia Ventricular[MeSHID:D017180] Off-Label Use[MeSHID:D056687] Stable angina[MeSHID:D060050] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Atrial Fibrillation[MeSHID:D001281] |
NA | approved,investigational | inhibitor |
| ranolazine | sodium channel protein | small molecule | NA | drugbank | Cardiac Arrhythmia[MeSHID:D001145] Acute Coronary Syndrome[MeSHID:D054058] Blood Platelets[MeSHID:D001792] Angina Pectoris[MeSHID:D000787] Heart[MeSHID:D006321] Tachycardia Ventricular[MeSHID:D017180] Off-Label Use[MeSHID:D056687] Stable angina[MeSHID:D060050] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Atrial Fibrillation[MeSHID:D001281] |
NA | approved,investigational | inhibitor |
| ranolazine | sodium channel protein | small molecule | NA | drugbank | Cardiac Arrhythmia[MeSHID:D001145] Acute Coronary Syndrome[MeSHID:D054058] Blood Platelets[MeSHID:D001792] Angina Pectoris[MeSHID:D000787] Heart[MeSHID:D006321] Tachycardia Ventricular[MeSHID:D017180] Off-Label Use[MeSHID:D056687] Stable angina[MeSHID:D060050] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Atrial Fibrillation[MeSHID:D001281] |
NA | approved,investigational | inhibitor |
| ranolazine | sodium channel protein | small molecule | NA | drugbank | Cardiac Arrhythmia[MeSHID:D001145] Acute Coronary Syndrome[MeSHID:D054058] Blood Platelets[MeSHID:D001792] Angina Pectoris[MeSHID:D000787] Heart[MeSHID:D006321] Tachycardia Ventricular[MeSHID:D017180] Off-Label Use[MeSHID:D056687] Stable angina[MeSHID:D060050] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Atrial Fibrillation[MeSHID:D001281] |
NA | approved,investigational | inhibitor |
| ranolazine | sodium channel protein | small molecule | NA | drugbank | Cardiac Arrhythmia[MeSHID:D001145] Acute Coronary Syndrome[MeSHID:D054058] Blood Platelets[MeSHID:D001792] Angina Pectoris[MeSHID:D000787] Heart[MeSHID:D006321] Tachycardia Ventricular[MeSHID:D017180] Off-Label Use[MeSHID:D056687] Stable angina[MeSHID:D060050] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Atrial Fibrillation[MeSHID:D001281] |
NA | approved,investigational | inhibitor |
| ranolazine | sodium channel protein | small molecule | NA | drugbank | Cardiac Arrhythmia[MeSHID:D001145] Acute Coronary Syndrome[MeSHID:D054058] Blood Platelets[MeSHID:D001792] Angina Pectoris[MeSHID:D000787] Heart[MeSHID:D006321] Tachycardia Ventricular[MeSHID:D017180] Off-Label Use[MeSHID:D056687] Stable angina[MeSHID:D060050] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Atrial Fibrillation[MeSHID:D001281] |
NA | approved,investigational | inhibitor |
| ranolazine | sodium channel protein | small molecule | NA | drugbank | Cardiac Arrhythmia[MeSHID:D001145] Acute Coronary Syndrome[MeSHID:D054058] Blood Platelets[MeSHID:D001792] Angina Pectoris[MeSHID:D000787] Heart[MeSHID:D006321] Tachycardia Ventricular[MeSHID:D017180] Off-Label Use[MeSHID:D056687] Stable angina[MeSHID:D060050] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Atrial Fibrillation[MeSHID:D001281] |
NA | approved,investigational | inhibitor |
| ranolazine | sodium channel protein | small molecule | NA | drugbank , DGIDB | Cardiac Arrhythmia[MeSHID:D001145] Acute Coronary Syndrome[MeSHID:D054058] Blood Platelets[MeSHID:D001792] Angina Pectoris[MeSHID:D000787] Heart[MeSHID:D006321] Tachycardia Ventricular[MeSHID:D017180] Off-Label Use[MeSHID:D056687] Stable angina[MeSHID:D060050] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Atrial Fibrillation[MeSHID:D001281] |
0.14 | approved,investigational | inhibitor,blocker |
| ranolazine | sodium channel protein | small molecule | NA | drugbank | Cardiac Arrhythmia[MeSHID:D001145] Acute Coronary Syndrome[MeSHID:D054058] Blood Platelets[MeSHID:D001792] Angina Pectoris[MeSHID:D000787] Heart[MeSHID:D006321] Tachycardia Ventricular[MeSHID:D017180] Off-Label Use[MeSHID:D056687] Stable angina[MeSHID:D060050] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Atrial Fibrillation[MeSHID:D001281] |
NA | approved,investigational | inhibitor |
| ranolazine | sodium channel protein | small molecule | NA | drugbank , DGIDB | Cardiac Arrhythmia[MeSHID:D001145] Acute Coronary Syndrome[MeSHID:D054058] Blood Platelets[MeSHID:D001792] Angina Pectoris[MeSHID:D000787] Heart[MeSHID:D006321] Tachycardia Ventricular[MeSHID:D017180] Off-Label Use[MeSHID:D056687] Stable angina[MeSHID:D060050] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Atrial Fibrillation[MeSHID:D001281] |
0.51 | approved,investigational | inhibitor,blocker |
| ranolazine | sodium channel protein | small molecule | NA | drugbank , DGIDB | Cardiac Arrhythmia[MeSHID:D001145] Acute Coronary Syndrome[MeSHID:D054058] Blood Platelets[MeSHID:D001792] Angina Pectoris[MeSHID:D000787] Heart[MeSHID:D006321] Tachycardia Ventricular[MeSHID:D017180] Off-Label Use[MeSHID:D056687] Stable angina[MeSHID:D060050] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Atrial Fibrillation[MeSHID:D001281] |
0.51 | approved,investigational | inhibitor |
| ranolazine | sodium channel protein | small molecule | NA | drugbank | Cardiac Arrhythmia[MeSHID:D001145] Acute Coronary Syndrome[MeSHID:D054058] Blood Platelets[MeSHID:D001792] Angina Pectoris[MeSHID:D000787] Heart[MeSHID:D006321] Tachycardia Ventricular[MeSHID:D017180] Off-Label Use[MeSHID:D056687] Stable angina[MeSHID:D060050] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Atrial Fibrillation[MeSHID:D001281] |
NA | approved,investigational | inhibitor |
| ranolazine | sodium channel protein | small molecule | NA | drugbank | Cardiac Arrhythmia[MeSHID:D001145] Acute Coronary Syndrome[MeSHID:D054058] Blood Platelets[MeSHID:D001792] Angina Pectoris[MeSHID:D000787] Heart[MeSHID:D006321] Tachycardia Ventricular[MeSHID:D017180] Off-Label Use[MeSHID:D056687] Stable angina[MeSHID:D060050] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Atrial Fibrillation[MeSHID:D001281] |
NA | approved,investigational | inhibitor |
| ranolazine | sodium channel protein | small molecule | NA | drugbank , DGIDB | Cardiac Arrhythmia[MeSHID:D001145] Acute Coronary Syndrome[MeSHID:D054058] Blood Platelets[MeSHID:D001792] Angina Pectoris[MeSHID:D000787] Heart[MeSHID:D006321] Tachycardia Ventricular[MeSHID:D017180] Off-Label Use[MeSHID:D056687] Stable angina[MeSHID:D060050] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Atrial Fibrillation[MeSHID:D001281] |
0.4 | approved,investigational | inhibitor |
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